scholarly journals Chemogenetic inhibition of trigeminal ganglion neurons attenuates behavioral and neural pain responses in a model of trigeminal neuropathic pain

2021 ◽  
Author(s):  
Olga A. Korczeniewska ◽  
Morgan H. James ◽  
Tali Eliav ◽  
Giannina Katzmann Rider ◽  
Jacqueline B Mehr ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Trigeminal Ganglion ◽  
Trigeminal Neuropathic Pain ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons ◽  
Pain Responses

scholarly journals Attenuation of pain-related behavior in a rat model of trigeminal neuropathic pain by viral-driven enkephalin overproduction in trigeminal ganglion neurons

2005 ◽  
Vol 11 (4) ◽  
pp. 608-616 ◽  
Author(s):  
Alice Meunier ◽  
Alban Latrémolière ◽  
Annie Mauborgne ◽  
Sylvie Bourgoin ◽  
Valérie Kayser ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Trigeminal Ganglion ◽  
Rat Model ◽  
Trigeminal Neuropathic Pain ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons

scholarly journals The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons

2017 ◽  
Vol 10 ◽  
Author(s):  
Douglas M. Lopes ◽  
Franziska Denk ◽  
Stephen B. McMahon
Keyword(s):  
Trigeminal Ganglion ◽  
Dorsal Root ◽  
Molecular Fingerprint ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons

Effects of WIN 55, 212-2 onI K current in cultured trigeminal ganglion neurons of rat

2005 ◽  
Vol 25 (2) ◽  
pp. 124-126
Author(s):  
Ming Zhangyin ◽  
Tan Yan ◽  
Fu Hui ◽  
Cao Xuehong ◽  
Pan Jianping ◽  
...  
Keyword(s):  
Trigeminal Ganglion ◽  
K Current ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons ◽  
Win 55

Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons

1996 ◽  
Vol 270 (6) ◽  
pp. C1807-C1814 ◽  
Author(s):  
L. Liu ◽  
S. A. Simon
Keyword(s):  
Trigeminal Ganglion ◽  
Acetylcholine Receptors ◽  
Ganglion Cells ◽  
Whole Cell Patch Clamp ◽  
Current Voltage ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons ◽  
Relationship Of ◽  
Current Voltage Relationship ◽  
Voltage Relationship

Nicotine and capsaicin produce many similar physiological responses that include pain, irritation, and vasodilation. To determine whether neuronal nicotine acetylcholine receptors (nAChR) are present on capsaicin-sensitive neurons, whole cell patch-clamp recordings were performed on rat trigeminal ganglion cells. It was found that approximately 20% of the total number of neurons tested was activated by both 100 microM nicotine and 1 nM capsaicin. Other subsets of neurons were activated by only one of these compounds, whereas a fourth subset was not activated by either compound. At -60 mV, the magnitude of the capsaicin-activated currents was about three times larger than the magnitude of the nicotine-activated currents. The current-voltage relationship of the nAChR exhibited marked rectification, such that for voltages > or = 0 mV the current was essentially zero. In contrast, the current-voltage relationship of the capsaicin-activated current was ohmic from +/- 60 mV. These data indicate the existence of subsets of capsaicin-sensitive afferent neurons.

scholarly journals Toll-like receptor 4 signaling in trigeminal ganglion neurons contributes tongue-referred pain associated with tooth pulp inflammation

2013 ◽  
Vol 10 (1) ◽  
pp. 139 ◽  
Author(s):  
Kinuyo Ohara ◽  
Kohei Shimizu ◽  
Shingo Matsuura ◽  
Bunnai Ogiso ◽  
Daisuke Omagari ◽  
...  
Keyword(s):  
Trigeminal Ganglion ◽  
Referred Pain ◽  
Tooth Pulp ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Pulp Inflammation ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons
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