Fabrication of a Highly Sensitive Glucose Biosensor Based on Immobilization of Osmium Complex and Glucose Oxidase onto Carbon Nanotubes Modified Electrode

2009 ◽  
Vol 21 (8) ◽  
pp. 909-917 ◽  
Author(s):  
Abdollah Salimi ◽  
Begard Kavosi ◽  
Rahman Hallaj ◽  
Ali Babaei
Author(s):  
Nicole Jaffrezic-Renault ◽  
Ilhem Rassas ◽  
Mohamed Braiek ◽  
Anne Bonhomme ◽  
François Bessueille ◽  
...  

In this work, an enzymatic sensor, based on a bionanocomposite film consisting of a polyelectrolyte complex (PEC) [Chitosan/kappa-carrageenan] doped with gold nanoparticles (AuNPs) encapsulating glucose oxidase (GOD) deposited on a gold electrode (Au) for glucose sensing, is described. Using the electrocatalytic synergy of AuNPs and GOD as a model of enzyme, the variation of the current (µA) as a function of the log of the glucose concentration (log [glucose]), shows 3 times higher sensitivity for the modified electrode (283.9) compared to that of the PEC/GOD modified electrode (93.7), with a detection limit of about 5 µM and a linearity range between 10µM and 7mM. The response of the PEC/AuNPs/GOD based biosensor also presents good reproducibility, stability and negligible interfering effects from ascorbic acid, uric acid, urea and creatinine. The applicability of the PEC/AuNPs/GOD based biosensor was tested in glucose-spiked saliva samples and acceptable recovery rates were obtained.


Sensors ◽  
2019 ◽  
Vol 19 (1) ◽  
pp. 154 ◽  
Author(s):  
Ilhem Rassas ◽  
Mohamed Braiek ◽  
Anne Bonhomme ◽  
Francois Bessueille ◽  
Guy Raffin ◽  
...  

In this work, an enzymatic sensor, based on a bionanocomposite film consisting of a polyelectrolyte complex (PEC) (Chitosan/kappa-carrageenan) doped with gold nanoparticles (AuNPs) encapsulating glucose oxidase (GOD) deposited on a gold electrode (Au) for glucose sensing, is described. Using the electrocatalytic synergy of AuNPs and GOD as a model of enzyme, the variation of the current (µA) as a function of the log of the glucose concentration (log [glucose]), shows three times higher sensitivity for the modified electrode (283.9) compared to that of the PEC/GOD modified electrode (93.7), with a detection limit of about 5 µM and a linearity range between 10 µM and 7 mM. The response of the PEC/AuNPs/GOD based biosensor also presents good reproducibility, stability, and negligible interfering effects from ascorbic acid, uric acid, urea, and creatinine. The applicability of the PEC/AuNPs/GOD based biosensor was tested in glucose-spiked saliva samples and acceptable recovery rates were obtained.


2022 ◽  
Author(s):  
Qiaoling Wu ◽  
Chun Ji ◽  
Lingli Zhang ◽  
Qingli Shi ◽  
Yuangen Wu ◽  
...  

The work presented here describes a highly sensitive and simple electrochemical sensor for the detection of Sudan I dye based on MoS2 heterogeneous nanosheets (1T@2H-MoS2) and carboxylated carbon nanotubes (cMWCNTs)...


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