scholarly journals Compartment‐specific 13 C metabolic flux analysis reveals boosted NADPH availability coinciding with increased cell‐specific productivity for IgG1 producing CHO cells after MTA treatment

2021 ◽  
Author(s):  
Andy Wiranata Wijaya ◽  
Natascha Verhagen ◽  
Attila Teleki ◽  
Ralf Takors
Keyword(s):  
Metabolic Flux Analysis ◽  
Cho Cells ◽  
Metabolic Flux ◽  
Specific Productivity ◽  
Flux Analysis

scholarly journals Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells

2011 ◽  
Vol 11 (1) ◽  
pp. 95 ◽  
Author(s):  
Susan C Burleigh ◽  
Teun van de Laar ◽  
Corné JM Stroop ◽  
Wout MJ van Grunsven ◽  
Niaobh O'Donoghue ◽  
...  
Keyword(s):  
Recombinant Protein ◽  
Metabolic Flux Analysis ◽  
Cho Cells ◽  
Metabolic Flux ◽  
Sugar Metabolism ◽  
Flux Analysis ◽  
Nucleotide Sugar

Intracellular metabolic flux analysis of CHO cells supplemented with wheat hydrolysates for improved mAb production and cell-growth

2014 ◽  
Vol 90 (2) ◽  
pp. 291-302 ◽  
Author(s):  
Hae Woo Lee ◽  
Andrew Christie ◽  
Jason A. Starkey ◽  
Erik K. Read ◽  
Seongkyu Yoon
Keyword(s):  
Cell Growth ◽  
Metabolic Flux Analysis ◽  
Cho Cells ◽  
Metabolic Flux ◽  
Flux Analysis ◽  
Mab Production

Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy

2010 ◽  
Vol 12 (2) ◽  
pp. 138-149 ◽  
Author(s):  
Chetan Goudar ◽  
Richard Biener ◽  
C. Boisart ◽  
Rüdiger Heidemann ◽  
James Piret ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Metabolic Flux Analysis ◽  
Cho Cells ◽  
Metabolic Flux ◽  
Perfusion Culture ◽  
Flux Analysis ◽  
Cosy Nmr

A detailed metabolic flux analysis of an underdetermined network of CHO cells

2010 ◽  
Vol 150 (4) ◽  
pp. 497-508 ◽  
Author(s):  
F. Zamorano ◽  
A.Vande Wouwer ◽  
G. Bastin
Keyword(s):  
Metabolic Flux Analysis ◽  
Cho Cells ◽  
Metabolic Flux ◽  
Flux Analysis
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