Trp53 sequence analysis of L5178Y cell line derivatives

2003 ◽  
Vol 42 (2) ◽  
pp. 122-124 ◽  
Author(s):  
Jennifer L. Hess ◽  
L. Scott Clark ◽  
Martha M. Moore
Keyword(s):  
Sequence Analysis ◽  
Cell Line ◽  
L5178y Cell

scholarly journals Ircinal E, a New Manzamine Derivative from the Indonesian Marine Sponge Acanthostrongylophora ingens

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Mousa AlTarabeen ◽  
Georgios Daletos ◽  
Weaam Ebrahim ◽  
Werner E. G. Müller ◽  
Rudolf Hartmann ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
High Resolution ◽  
Cell Line ◽  
Marine Sponge ◽  
High Resolution Mass Spectrometry ◽  
Two Dimensional ◽  
Meoh Extract ◽  
L5178y Cell ◽  
Resolution Mass

Chemical investigation of the MeOH extract of the sponge Acanthostrongylophora ingens afforded the new manzamine derivative ircinal E (1), in addition to six known metabolites (2–7). The structure of the new compound was unequivocally elucidated using one- and two-dimensional NMR spectroscopy, as well as high-resolution mass spectrometry. Compounds 1–6 exhibited strong to moderate cytotoxicity against the murine lymphoma L5178Y cell line with IC50 values ranging from 2.8 to 21.7 μM.

scholarly journals Isolation and characterization of the murine lymphoma L5178Y cell line highly resistant to 5-fluorouracil.

1980 ◽  
Vol 3 (8) ◽  
pp. 390-394 ◽  
Author(s):  
FUMIHIKO KANZAWA ◽  
AKIO HOSHI ◽  
KAZUO KURETANI
Keyword(s):  
Cell Line ◽  
Murine Lymphoma ◽  
Isolation And Characterization ◽  
L5178y Cell

scholarly journals Comparative ompA gene sequence analysis of Rickettsia felis-like bacteria detected in Haemaphysalis sulcata ticks and isolated in the mosquito C6/36 cell line

2009 ◽  
Vol 15 ◽  
pp. 265-266 ◽  
Author(s):  
M. Gracner ◽  
T. Avsic-Zupanc ◽  
V. Punda-Polic ◽  
J. Dolinsek ◽  
D. Bouyer ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Cell Line ◽  
Gene Sequence ◽  
Ompa Gene ◽  
Rickettsia Felis ◽  
Gene Sequence Analysis

scholarly journals Nucleotide sequence analysis of the linked left and right hand terminal regions of adenovirus type 5 DNA present in the transformed rat cell line 5RK20

1982 ◽  
Vol 10 (7) ◽  
pp. 2189-2198 ◽  
Author(s):  
Lambertus Visser ◽  
Annemie C.M.B. Reemst ◽  
Alphonsus D.M. van Mansfeld ◽  
Thomas H. Rozijn
Keyword(s):  
Sequence Analysis ◽  
Nucleotide Sequence ◽  
Cell Line ◽  
Adenovirus Type ◽  
Nucleotide Sequence Analysis ◽  
Right Hand ◽  
Left And Right ◽  
Adenovirus Type 5

scholarly journals Sequence analysis of mitochondrial DNA in a mouse cell line resistant to chloramphenicol and oligomycin.

1983 ◽  
Vol 3 (10) ◽  
pp. 1694-1702 ◽  
Author(s):  
E F Slott ◽  
R O Shade ◽  
R A Lansman
Keyword(s):  
Mitochondrial Dna ◽  
Sequence Analysis ◽  
Cell Line ◽  
Mammalian Cells ◽  
Mouse Cell ◽  
Mitochondrial Atpase ◽  
Dna Molecules ◽  
Single Nucleotide Change ◽  
In The Wild ◽  
Atpase 6

A mouse L-cell line, designated 111-OB3, is described which is resistant to two drugs, chloramphenicol and oligomycin. The cells contain two types of mitochondrial DNA molecules, in roughly equal proportions, which differ in that one is cleaved by endonuclease EcoRI at a novel site within the coding sequence for subunit 6 of the mitochondrial ATPase (ATPase-6). Sequence analysis reveals that the cleavage site was created by a single transversion which predicts a replacement of valine in the wild-type ATPase-6 by glutamic acid. The replacement occurs in a hydrophobic amino acid sequence which is highly conserved in mouse, human, and bovine proteins. The position of the replacement is similar to a substitution observed in one class of yeast mutants resistant to oligomycin. Both of the mitochondrial DNA molecules in 111-OB3 also have a single nucleotide change in the gene encoding the large (16S) rRNA. These observations are consistent with the hypothesis that oligomycin resistance in mammalian cells can be cytoplasmically determined and can result from alterations in ATPase-6. The appearance of the mutation before selection in oligomycin suggests a model for the origin of mitochondrial mutations in mammalian cells.

Steady-state persistence of respiratory syncytial virus in a macrophage-like cell line and sequence analysis of the persistent viral genome

2021 ◽  
pp. 198367
Author(s):  
Ximena Ruiz-Gómez ◽  
Joel Armando Vázquez-Pérez ◽  
Oscar Flores-Herrera ◽  
Mercedes Esparza-Perusquía ◽  
Carlos Santiago-Olivares ◽  
...  
Keyword(s):  
Steady State ◽  
Respiratory Syncytial Virus ◽  
Sequence Analysis ◽  
Cell Line ◽  
Viral Genome ◽  
Syncytial Virus

scholarly journals Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered.

1988 ◽  
Vol 85 (9) ◽  
pp. 3052-3056 ◽  
Author(s):  
S. N. Finver ◽  
K. Nishikura ◽  
L. R. Finger ◽  
F. G. Haluska ◽  
J. Finan ◽  
...  
Keyword(s):  
T Cell ◽  
Sequence Analysis ◽  
Cell Line ◽  
Chromosome Translocation ◽  
Human Leukemia ◽  
Regulatory Regions ◽  
Myc Oncogene
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