Relative telomere length and gene expression of shelterin complex proteins among vinyl chloride monomer‐exposed workers in China

2019 ◽  
Vol 60 (4) ◽  
pp. 361-367 ◽  
Author(s):  
Guo‐Qiao Zheng ◽  
Guang‐Hui Zhang ◽  
Han‐Tian Wu ◽  
Yu‐Ting Tu ◽  
Wei Tian ◽  
...  
Keyword(s):  
Gene Expression ◽  
Telomere Length ◽  
Vinyl Chloride ◽  
Vinyl Chloride Monomer ◽  
Shelterin Complex ◽  
Relative Telomere Length ◽  
Exposed Workers

Patterns of Relative Telomere Length is Associated With hTERT Gene Expression in the Tissue of Patients With Breast Cancer

2019 ◽  
Vol 19 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Karuvaje Thriveni ◽  
Anisha Raju ◽  
Rekha V. Kumar ◽  
Swamyvelu Krishnamurthy ◽  
Ramesh Chaluvarayaswamy
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Telomere Length ◽  
Htert Gene ◽  
Relative Telomere Length

Association of Telomere Length With Chromosomal Damage Among Chinese Workers Exposed to Vinyl Chloride Monomer

2017 ◽  
Vol 59 (12) ◽  
pp. e252-e256 ◽  
Author(s):  
Guo-qiao Zheng ◽  
Guang-hui Zhang ◽  
Xiao-wen Xu ◽  
Jin-wei Wang ◽  
Li-bo Yu ◽  
...  
Keyword(s):  
Telomere Length ◽  
Vinyl Chloride ◽  
Vinyl Chloride Monomer ◽  
Chromosomal Damage ◽  
Chinese Workers

scholarly journals Biochemical effects of vinyl chloride monomer on the liver of occupationally exposed workers

2000 ◽  
Vol 6 (5-6) ◽  
pp. 979-986
Author(s):  
A. A. Saad ◽  
S. M. El Sewedy ◽  
G. A. Bader ◽  
S. M. Mousa ◽  
M. M. Mahdy
Keyword(s):  
Vinyl Chloride ◽  
Fatty Infiltration ◽  
Activity Level ◽  
Vinyl Chloride Monomer ◽  
Medical Surveillance ◽  
Glutathione S Transferase ◽  
Biochemical Effects ◽  
Exposed Workers ◽  
Occupationally Exposed ◽  
Liver Enlargement

We investigated the effects of vinyl chloride monomer exposure on the liver of 86 workers by measuring beta-glucuronidase, arylsulfatase A, adenosine deaminase, 5'-nucleotidase and routine liver function enzymes in the sera of the workers. In 21 of them, three or more of these parameters were raised, with a significant decrease in the level of blood glutathione and a significant increase in the enzyme activity level of glutathione S-transferase. Of these 21 workers, 14 had fatty liver infiltration, 8 of whom were also suffering from liver enlargement. Also, 4 workers had liver enlargement without fatty infiltration and 3 had enlarged spleens. The study highlights the need for vigilance in environmental monitoring and medical surveillance of workers exposed to this chemical.

Sign in / Sign up

Export Citation Format

Share Document