Apolipoprotein E ?4 allele is not associated with the cognitive impairment in community-dwelling normal elderly individuals

This study aimed to clarify the emotional experiences of a community-dwelling sample of elderly individuals with mild cognitive impairment and their families. The participants included an elderly man and his wife and an elderly woman and her daughterin- law. Data were collected using semi-structured interviews and analyzed by using a qualitative inductive method. In total, 212 codes were extracted from the interviews and categorized into 37 sub-categories. Finally, we obtained the following 4 categories: Bewilderment regarding memory decline, Avoidance of neighborly relations, Fluctuation of confidence in the family, and Desire to maintain a healthy life.

Download Full-text

Antidepressant use and associated factors among the elderly: the Bambuí Project

Ciência & Saúde Coletiva ◽

10.1590/1413-812320152012.09662015 ◽

2015 ◽

Vol 20 (12) ◽

pp. 3797-3804 ◽

Cited By ~ 3

Author(s):

Adriano Roberto Tarifa Vicente ◽

Érico Castro-Costa ◽

Breno Satler Diniz ◽

Josélia Oliveira Araújo Firmo ◽

Maria Fernanda Lima-Costa ◽

...

Keyword(s):

Cognitive Impairment ◽

Functional Disability ◽

Female Gender ◽

The Elderly ◽

Population Based ◽

Community Dwelling ◽

Elderly Individuals ◽

Key Factor ◽

Antidepressant Use ◽

Reported Health

Abstract This study examined the factors associated with antidepressant use among community-dwelling elderly individuals. Data collected from the Bambuí Project, a population-based study on aging and health with a cohort of 1,606 elderly individuals, were used. Gender, age, education, marital status, household income and cohabitation status were the sociodemographic characteristics investigated. Health conditions included self-reported health, number of chronic diseases, depressive symptoms, cognitive impairment and functional disability. Poisson regression with robust variance was used to test associations and to estimate prevalence ratios with 95% confidence intervals. The prevalence of antidepressant use was 8.4%. After multivariate analysis, antidepressant use was associated with the female gender (PR = 2.96; 95%CI 1.82-4.81), being single or divorced (PR = 0.48; 95%CI 0.25-0.91), cognitive impairment (PR = 0.44; 95%CI 0.24-0.84) and worse self-reported health (poor/very poor) (PR=1.86; 95%CI 1.11-3.10). The results are similar to those observed in several other studies conducted in higher-income countries and suggest that self-reported health in the elderly population of Bambuí is a key factor in the decision to use antidepressants.

Download Full-text

Apolipoprotein E Polymorphism and Cognitive Impairment in A Bi-Ethnic Community-Dwelling Elderly Sample

Alzheimer Disease & Associated Disorders ◽

10.1097/00002093-200201000-00002 ◽

2002 ◽

Vol 16 (1) ◽

pp. 8-14 ◽

Cited By ~ 7

Author(s):

Dylan G. Harwood ◽

Warren W. Barker ◽

Raymond L. Ownby ◽

Michael Mullan ◽

Ranjan Duara

Keyword(s):

Cognitive Impairment ◽

Apolipoprotein E ◽

Community Dwelling ◽

Ethnic Community ◽

Apolipoprotein E Polymorphism

Download Full-text

Cognitive Consequences of Multiple Lacunes and Leukoaraiosis as Vascular Cognitive Impairment in Community-Dwelling Elderly Individuals

Journal of Stroke and Cerebrovascular Diseases ◽

10.1016/j.jstrokecerebrovasdis.2008.07.010 ◽

2009 ◽

Vol 18 (1) ◽

pp. 32-37 ◽

Cited By ~ 40

Author(s):

Hiroshi Koga ◽

Yuki Takashima ◽

Ryo Murakawa ◽

Akira Uchino ◽

Takefumi Yuzuriha ◽

...

Keyword(s):

Cognitive Impairment ◽

Vascular Cognitive Impairment ◽

Community Dwelling ◽

Elderly Individuals ◽

Cognitive Consequences

Download Full-text

Falls, Cognitive Function, and Balance Profiles of Singapore Community-Dwelling Elderly Individuals: Key Risk Factors

Geriatric Orthopaedic Surgery & Rehabilitation ◽

10.1177/2151458517745989 ◽

2017 ◽

Vol 8 (4) ◽

pp. 256-262 ◽

Cited By ~ 4

Author(s):

Mei Teng Woo ◽

Keith Davids ◽

Jarmo Liukkonen ◽

Jia Yi Chow ◽

Timo Jaakkola

Keyword(s):

Cognitive Impairment ◽

Cognitive Function ◽

Oldest Old ◽

Age Groups ◽

Berg Balance Scale ◽

Community Dwelling ◽

Risk Of Falling ◽

Elderly Age ◽

Elderly Individuals ◽

Increased Risk

Objective: This study compared occurrence of falls, cognitive function, and balance profiles across participants in elderly age categories, investigating associations between the 3 aspects in a sample of Singapore’s elderly population. Method: Community-dwelling elderly individuals (N = 385) were randomly recruited and grouped into “young-old (65-74 years),” “medium-old (75-84 years),” and “oldest-old (above 85 years)” groups. The Fallproof Health and Activity questionnaire, adapted Mini-Mental State Examination (MMSE), and Berg Balance Scale (BBS) tests were used to survey information related to falls, cognition, and balance profiles. Results: Findings revealed significant differences in MMSE and BBS scores across the age groups. Participants with mild cognitive impairment (odds ratio [OR] = 1.87, 95% confidence interval [CI] = 1.08-3.25) and BBS score ≤40 (OR = 0.25, 95% CI = 0.14-0.46) were at the highest risk of falling. Conclusion: Community-dwelling elderly individuals with subtle cognitive impairment and BBS scores ≤40 displayed an increased risk of falling.

Download Full-text

Utility of handgrip strength cut-offs for identification of weakness and disability in community-dwelling older people with mild cognitive impairment and Alzheimer’s disease

Jornal Brasileiro de Psiquiatria ◽

10.1590/0047-2085000000248 ◽

2019 ◽

Vol 68 (4) ◽

pp. 208-214 ◽

Cited By ~ 1

Author(s):

Ivan Abdalla Teixeira ◽

Felipe de Oliveira Silva ◽

José Vinícius Alves Ferreira ◽

Jéssica Plácido ◽

Valeska Marinho ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Older People ◽

Handgrip Strength ◽

Community Dwelling ◽

Cross Sectional ◽

Elderly Individuals ◽

European Working

ABSTRACT Objectives To evaluate the utility of handgrip strength cut-offs for the identification of weakness and Instrumental Activities of Daily Living (IADL) disability in elderly people with neurocognitive disorders. Methods Cross-sectional study of community-dwelling elderly individuals with Alzheimer’s disease (AD, n = 40) and mild cognitive impairment (MCI, n = 22); healthy individuals (n = 36) were recruited as controls. Handgrip cut-offs included European Working Group for Sarcopenic Older People (EWGSOP2), Cardiovascular Healthy Study (CHS) and the Frailty in Brazilian Older People Study from Rio de Janeiro (FIBRA RJ) cut-offs. Handgrip strength indexes were calculated by dividing handgrip strength values by cut-off values and the weakness prevalence for each cut-off value was compared among groups. Correlation analyses were employed to evaluate the relationship between Lawton Scale and handgrip strength (crude value and indexes). Results All handgrip strength indexes were lower in the AD group (p < 0.05), whereas the prevalence of weakness was significantly higher in the AD group only when the CHS cut-off was applied (AD = 47.5%, MCI and control = 18.2%, p < 0.01). Significantly positive correlations were identified between the Lawton ADL scale and handgrip indexes for all cut-offs (p < 0.05), but not between Lawton scale and crude handgrip (p = 0.75). Conclusions Only the CHS cut-off allowed proper differentiation of the weakness prevalence between groups. In addition, adjusting handgrip strength values according to cut-offs was necessary to determine the correlation between strength and disability in cognitively impaired elderly individuals.

Download Full-text

PERFORMANCE OF COMMUNITY DWELLING INDIVIDUALS IN SEMANTIC, LETTER AND ACTION VERB VERBAL FLUENCY TASKS

10.5327/1980-5764.rpda093 ◽

2021 ◽

Author(s):

Anna Cavalcanti ◽

Victória Osaki ◽

Felipe Bezerra ◽

Katerina Lukasova ◽

Maria Carthery- Goulart

Keyword(s):

Cognitive Impairment ◽

Cognitive Decline ◽

Verbal Fluency ◽

Community Dwelling ◽

Depression And Anxiety ◽

Initial Screening ◽

Elderly Individuals ◽

The Mean ◽

Switching Strategies ◽

Cognitive Impairment No Dementia

Background: Verbal fluency (VF) tasks are usually employed to screen for cognitive decline. Letter (LF) and semantic (SF) VF were extensively used. Action VF (AF) was less explored, however it can be helpful to discriminate between clinical groups. Objective: 1.To characterize performance and strategies in VF in elderly individuals recruited in the community; 2.To obtain preliminary norms for AF. Methods: 121 community dwelling seniors (77.7% women, age (67.5±5.4) and schooling (11±4.4), recruited by convenience. After initial screening 65 fulfilled criteria for controls based on MOANS (G1) and 56 (G2) presented scores in the MMSE (27.4±2.1) compatible with cognitive impairment no dementia (CIND). We analysed the number of correctly evocated items as well as clustering and switching strategies. Results: 33% of the sample had scores in the MMSE compatible with CIND and among those, 25.6% presented GDS and GAI scores compatible with depression and anxiety. For both groups, scores were higher for SF, followed by AF and LF. The interaction between VF and Group was significant only for SF (P P<0.05), with lower scores for G2. For G1 and G2 the mean total scores for SF, LF and AF were respectively 16.5(± 4.6), 12.4(±5.3), 14.3(±5.7) and 13.6(±4.7) and 11.4(±3.7), 13.3(±6.3). Conclusion: SF was more impaired than LF and AF in community dwelling individuals with MMSE scores compatible with CDND.

Download Full-text