scholarly journals Transcranial direct current stimulation over the sensory‐motor regions inhibits gamma synchrony

2019 ◽  
Vol 40 (9) ◽  
pp. 2736-2746 ◽  
Author(s):  
Giovanni Pellegrino ◽  
Giorgio Arcara ◽  
Giovanni Di Pino ◽  
Cristina Turco ◽  
Matteo Maran ◽  
...  
2015 ◽  
Vol 30 (3) ◽  
pp. 178-184 ◽  
Author(s):  
Jaume Rosset-Llobet ◽  
Sílvia Fàbregas-Molas ◽  
Álvaro Pascual-Leone

Task-specific focal hand dystonia can disable affected individuals. Although neurorehabilitation techniques such as sensory motor retuning can result in complete recovery in some patients, it requires many months of treatment. Combining transcranial direct current stimulation (tDCS) with neurorehabilitation is a new and promising approach that can help these patients. However, the results in different studies are contradictory. OBJECTIVE: Analyze whether delivering tDCS (cathode over left and anode over right parietal region) during the neurorehabilitation process for musicians with dystonia can increase the effectiveness of therapy. METHOD: A parallel double-blind randomized design was used to study 30 musicians with right-hand primary focal dystonia. All patients underwent a 2-week course of neurorehabilitation based on sensory motor retuning therapy coupled with either real or sham tDCS for the first 30 minutes of each daily 1-hour therapy session (total 10 sessions). The therapist and patient were blind to the tDCS condition. A dystonia severity score was obtained before and after the 2-week protocol. The therapist also rated the evolution of each patient. RESULTS: Both groups significantly improved their dystonia severity score during the 2 weeks. Score differences were 88.23 (±40.51) and 63.36 (±30.57) for the active and sham groups, respectively. The active group showed a statistically significant greater improvement. CONCLUSIONS: Biparietal tDCS with left-sided cathode is a safe technique that does not interfere with the neurorehabilitation procedure and can increase therapy effectiveness in rehabilitation patients with right-hand task-specific focal dystonia.


2014 ◽  
Vol 29 (1) ◽  
pp. 16-18 ◽  
Author(s):  
Jaume Rosset-Llobet ◽  
Sílvia Fàbregas-Molas ◽  
Álvaro Pascual-Leone

Sensory-motor retuning (SMR) can help the symptoms of task-specific focal hand dystonia. However, effects vary across patients and take many sessions. Here, we present proof of principle evidence that transcranial direct current stimulation (tDCS) can enhance these effects. We compared the effects of a combined tDCS-SMR protocol (n=4 patients) with the efficacy of SMR alone (n=30 patients). All 4 patients treated with the combined protocol showed greater improvement than those undergoing SMR alone. Results encourage a larger, parallel-group clinical trial with sham tDCS control.


2009 ◽  
Vol 40 (01) ◽  
Author(s):  
F Buttkus ◽  
V Baur ◽  
HC Jabusch ◽  
M Weidenmüller ◽  
S Schneider ◽  
...  

2014 ◽  
Vol 33 (05) ◽  
pp. 382-386
Author(s):  
A. Hasan ◽  
S. Dehning ◽  
D. Keeser ◽  
I. Hummel ◽  
P. Falkai ◽  
...  

Zusammenfassung Gegenstand und Ziel: Die transkranielle Gleichstromstimulation (transcranial direct current stimulation, tDCS) wird als neues nicht invasives Hirnstimulationsverfahren für die Behandlung neurologischer und psychiatrischer Erkrankungen untersucht. Mittlerweile gibt es Fallberichte und eine randomisierte, kontrollierte Pilotstudie zur Behandlung akustischer Halluzinationen sowie der Negativsymptomatik bei Schizophrenie. Fallbericht: Im vorliegenden Fallbericht wurde ein Patient mit therapieresistenter Symptomatik bei paranoider Schizophrenie drei Wochen lang mit anodaler tDCS über dem linken dorsolateralen und kathodaler tDCS über dem rechten dorsolateralen Kortex behandelt. Ergebnisse: Es zeigte sich eine Verbesserung von Affektivität und Kognition, die Positivsymptome blieben jedoch nahezu unverändert. Klinische Relevanz: Die bifrontale tDCS stellt eine nebenwirkungsarme neue Behandlungsform dar und sollte in der Anwendung bei Erkrankungen aus dem schizophrenen Formenkreis weiter untersucht werden.


2017 ◽  
Vol 11 (3) ◽  
pp. 133-142 ◽  
Author(s):  
David J. Schretlen ◽  
Joseph J. van Steenburgh ◽  
Mark Varvaris ◽  
Tracy D. Vannorsdall ◽  
Megan A. Andrejczuk ◽  
...  

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