scholarly journals A data‐driven approach to stimulus selection reveals an image‐based representation of objects in high‐level visual areas

2019 ◽  
Vol 40 (16) ◽  
pp. 4716-4731 ◽  
Author(s):  
David D. Coggan ◽  
Afrodite Giannakopoulou ◽  
Sanah Ali ◽  
Burcu Goz ◽  
David M. Watson ◽  
...  
2020 ◽  
Vol 103 (9) ◽  
pp. 4913-4924
Author(s):  
Irmak Sargin ◽  
Charmayne E. Lonergan ◽  
John D. Vienna ◽  
John S. McCloy ◽  
Scott P. Beckman

2005 ◽  
Vol 10 (4) ◽  
pp. 183-192 ◽  
Author(s):  
Doug Burns

Abstract Since its inception in early 2000, Vanderbilt University's Peripherally Inserted Central Catheter (PICC) Service has experienced a high level of success as measured by high proficiency rates and increasing patient procedures each year, low complication rates during and after PICC placements, and an increasing scope of influence within the Vanderbilt University Medical Center and Children's Hospital, the surrounding community, and in the Southeastern United States. Primary drivers of the PICC Service's continuing success include consistent applications of technique and technology, a data-driven approach to assessing the program's progress, and appropriately managing customers' expectations and needs. Over the past five years, data were collected on more than 12,500 PICC placements performed in this specialized nursing program. Retrospective analyses of the data demonstrate an increasing rate of successful placements (from 87.2% to 92.4%) since the program's inception in 2000 to late 2004. Furthermore, the choice of PICC technology has had a significant impact on the odds for occlusion or infection. The Vanderbilt PICC Service provides a model by which other programs can be established, maintained, and expanded into advanced practice.


2017 ◽  
Vol 17 (10) ◽  
pp. 29
Author(s):  
David Coggan ◽  
David Watson ◽  
Tom Hartley ◽  
Daniel Baker ◽  
Timothy Andrews

2021 ◽  
Author(s):  
Jordan Dotson ◽  
Eric Anslyn ◽  
Matthew Sigman

Dynamic covalent chemistry-based sensors have recently emerged as powerful tools to rapidly determine the enantiomeric excess of organic small molecules. While a bevy of sensors have been developed, those for flexible molecules with stereocenters remote to the functional group that binds the chiroptical sensor remain scarce. In this study, we develop an iterative, data-driven workflow to design and analyze a chiroptical sensor capable of assessing challenging acyclic γ-stereogenic alcohols. Fol-lowing sensor optimization, the mechanism of sensing was probed with a combination of computational parameterization of the sensor molecules, statistical modeling, and high-level density functional theory (DFT) calculations. These were used to elucidate the mechanism of stereochemical recognition and revealed that competing attractive non-covalent interactions (NCIs) determine the overall performance of the sensor. It is anticipated that the data-driven workflows developed herein will be generally applicable to the development and understanding of dynamic covalent and supramolecular sensors.


Author(s):  
Virginia Fani ◽  
Bianca Bindi ◽  
Romeo Bandinelli

HVLV environments are characterized by high product variety and small lot production, pushing companies to recursively design and optimize their production systems in a very short time to reach high-level performance. To increase their competitiveness, companies belonging to these industries, often SMEs working as third parties, ask for decision-making tools to support them in a quick and reactive reconfiguration of their production lines. Traditional discrete event simulation models, widely studied in the literature to solve production-related issues, do not allow real-time support to business decisions in dynamic contexts, due to the time-consuming activities needed to re-align parameters to changing environments. Data-driven approach overcomes these limitations, giving the possibility to easily update input and quickly rebuild the model itself without any changes in the modeling code. The proposed data-driven simulation model has also been interfaced with a commonly-used BI tool to support companies in the iterative comparison of different scenarios to define the optimal resource allocation for the requested production plan. The simulation model has been implemented into a SME operating in the footwear industry, showing how this approach can be used by companies to increase their performance even without a specific knowledge in building and validating simulation models.


Author(s):  
Sebastian Herzog ◽  
Florentin Wörgötter

AbstractDynamic systems are usually described by differential equations, but formulating these equations requires a high level of expertise and a detailed understanding of the observed system to be modelled. In this work, we present a data-driven approach, which tries to find a parameterization of neural differential equations system to describe the underlying dynamic of the observed data. The presented method is applied to a multi-agent system with thousand agents.


2021 ◽  
Author(s):  
Yiyi Yu ◽  
Jeffrey N. Stirman ◽  
Christopher R. Dorsett ◽  
Spencer L. Smith

Mice have a constellation of higher visual areas, but their functional specializations are unclear. Here, we used a data-driven approach to examine neuronal representations of complex visual stimuli across mouse higher visual areas, measured using large field-of-view two-photon calcium imaging. Using specialized stimuli, we found higher fidelity representations of texture in area LM, compared to area AL. Complementarily, we found higher fidelity representations of motion in area AL, compared to area LM. We also observed this segregation of information in response to naturalistic videos. Finally, we explored how popular models of visual cortical neurons could produce the segregated representations of texture and motion we observed. These selective representations could aid in behaviors such as visually guided navigation.


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