Oncologic results of the surgical salvage of recurrent laryngeal squamous cell carcinoma in a multicentric retrospective series: Emerging role of supracricoid partial laryngectomy

Head & Neck ◽  
2014 ◽  
Vol 37 (1) ◽  
pp. 84-91 ◽  
Author(s):  
Marco de Vincentiis ◽  
Armando De Virgilio ◽  
Francesco Bussu ◽  
Roberto Gallus ◽  
Andrea Gallo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Partial Laryngectomy ◽  
Supracricoid Partial Laryngectomy ◽  
Oncologic Results ◽  
Surgical Salvage

The oncologic radicality of supracricoid partial laryngectomy with cricohyoidopexy in the treatment of advanced N0-N1 laryngeal squamous cell carcinoma

2012 ◽  
Vol 122 (4) ◽  
pp. 826-833 ◽  
Author(s):  
Armando De Virgilio ◽  
Massimo Fusconi ◽  
Andrea Gallo ◽  
Antonio Greco ◽  
Se-Heon Kim ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Partial Laryngectomy ◽  
Supracricoid Partial Laryngectomy

scholarly journals Diagnostic Role of Dysregulated Circular RNA hsa_circ_0036722 in Laryngeal Squamous Cell Carcinoma

2020 ◽  
Vol Volume 13 ◽  
pp. 5709-5719
Author(s):  
Yang Guo ◽  
Qiang Huang ◽  
Juan Zheng ◽  
Chi-Yao Hsueh ◽  
Xiaohui Yuan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Circular Rna ◽  
Diagnostic Role

The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma

2015 ◽  
Vol 126 (4) ◽  
pp. E148-E155 ◽  
Author(s):  
Antonio Greco ◽  
Armando De Virgilio ◽  
Maria Ida Rizzo ◽  
Fabio Pandolfi ◽  
Davide Rosati ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Role ◽  
E Cadherin

Supracricoid partial laryngectomy for non-squamous cell carcinoma of the larynx

2001 ◽  
Vol 115 (5) ◽  
pp. 388-392 ◽  
Author(s):  
David Veivers ◽  
Andréa de Vito ◽  
Kuauhyama Luna-Ortiz ◽  
Daniel Brasnu ◽  
Ollivier Laccourreye
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Total Laryngectomy ◽  
Case Series ◽  
Distant Metastases ◽  
Partial Laryngectomy ◽  
Potential Utility ◽  
Supracricoid Partial Laryngectomy ◽  
Carcinoma Of The Larynx

The objective of this paper was to evaluate the potential utility of supracricoid partial laryngectomies (SCPLS) for non-squamous cell carcinoma of the larynx. To illustrate our management of such tumours we present a case series based on six patients. Local control was achieved in five patients, with the sixth being salvaged by total laryngectomy and post-operative radiation therapy. Three of the six patients died of distant metastases. We concluded that supracricoid partial laryngectomies should become part of the armamentarium of the otolaryngologist - head and neck surgeon for non-squamous cell carcinoma of the larynx.

Role of miR-145 in human laryngeal squamous cell carcinoma

Head & Neck ◽  
2015 ◽  
Vol 38 (2) ◽  
pp. 260-266 ◽  
Author(s):  
Omer Faruk Karatas ◽  
Betul Yuceturk ◽  
Ilknur Suer ◽  
Mehmet Yilmaz ◽  
Harun Cansiz ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma

scholarly journals MicroRNA-625 inhibits cell invasion and epithelial–mesenchymal transition by targeting SOX4 in laryngeal squamous cell carcinoma

2019 ◽  
Vol 39 (1) ◽  
Author(s):  
Yuan Li ◽  
Chenjuan Tao ◽  
Lili Dai ◽  
Caixia Cui ◽  
Chaohui Chen ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Critical Role ◽  
Luciferase Reporter ◽  
Migration And Invasion ◽  
Mesenchymal Transition ◽  
Expression Levels

AbstractIntroduction: Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignant cancer, but the molecular mechanisms underlying its development and progression remain largely elusive. The purpose of the present study is to investigate the expression profile and functional role of microRNA-625 (miR-625) in LSCC.Materials and methods: LSCC tissues and adjacent normal tissues were collected from 86 LSCC patients. The expression levels of miR-625 and SOX4 mRNA in tissues and cells were detected by RT-qPCR analysis. The expression levels of SOX4 and EMT-related proteins were detected by western blot analysis. In vitro cell proliferation, migration, and invasion were detected by MTT assay, colony formation assay, wound healing assay, and transwell invasion assay, respectively. Dual-luciferase reporter assay was performed to verify the binding relationship between miR-625 and the 3′-UTR of SOX4.Results: The results demonstrated that miR-625 is significantly down-regulated in clinical LSCC tissues, and its low expression may be closely associated with unfavorable clinicopathological characteristics of LSCC patients. Overexpression of miR-625 significantly suppressed the proliferation, migration, invasion, and EMT of LSCC cells. Furthermore, SOX4 was validated as a direct target of miR-625 in LSCC cells, and rescue experiments suggested that restoration of SOX4 blocked the tumor suppressive role of miR-625 in LSCC cells.Conclusions: Taken together, these findings highlighted a critical role of miR-625 in the pathogenesis of LSCC, and restoration of miR-625 could be considered as a potential therapeutic strategy against this fatal disease.

The prognostic role of the epithelial-mesenchymal transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma

2015 ◽  
Vol 67 (4) ◽  
pp. 491-500 ◽  
Author(s):  
Rocco Cappellesso ◽  
Gino Marioni ◽  
Marika Crescenzi ◽  
Luciano Giacomelli ◽  
Vincenza Guzzardo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Epithelial Mesenchymal Transition ◽  
Prognostic Role ◽  
Mesenchymal Transition ◽  
E Cadherin

scholarly journals Biological evidence for a causal role of HPV16 in a small fraction of laryngeal squamous cell carcinoma

2013 ◽  
Vol 109 (1) ◽  
pp. 172-183 ◽  
Author(s):  
G Halec ◽  
D Holzinger ◽  
M Schmitt ◽  
C Flechtenmacher ◽  
G Dyckhoff ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Causal Role ◽  
Biological Evidence
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