scholarly journals Dietary and stored iron as predictors of breast cancer risk: A nested case-control study in Shanghai

2009 ◽  
Vol 125 (5) ◽  
pp. 1110-1117 ◽  
Author(s):  
Amber B. Moore ◽  
Jackilen Shannon ◽  
Chu Chen ◽  
Johanna W. Lampe ◽  
Roberta M. Ray ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

Circulating levels of perfluoroalkylated compounds and breast cancer risk: Evidence from a nested case-control study

2018 ◽  
Vol 66 ◽  
pp. S245
Author(s):  
F.R. Mancini ◽  
G. Cano-Sancho ◽  
J. Gabaretti ◽  
P. Marchand ◽  
J.-P. Antignac ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Circulating Levels ◽  
Control Study

scholarly journals Circulating carotenoids and breast cancer among high-risk individuals

2020 ◽  
Author(s):  
Cheng Peng ◽  
Chi Gao ◽  
Donghao Lu ◽  
Bernard A Rosner ◽  
Oana Zeleznik ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Genetic Risk ◽  
Case Control Study ◽  
Case Control ◽  
Polygenic Risk Score ◽  
Nested Case Control ◽  
Control Study

ABSTRACT Background Carotenoids represent 1 of few modifiable factors to reduce breast cancer risk. Elucidation of interactions between circulating carotenoids and genetic predispositions or mammographic density (MD) may help inform more effective primary preventive strategies in high-risk populations. Objectives We tested whether women at high risk for breast cancer due to genetic predispositions or high MD would experience meaningful and greater risk reduction from higher circulating levels of carotenoids in a nested case-control study in the Nurses’ Health Studies (NHS and NHSII). Methods This study included 1919 cases and 1695 controls in a nested case-control study in the NHS and NHSII. We assessed both multiplicative and additive interactions. RR reductions and 95% CIs were calculated using unconditional logistic regressions, adjusting for matching factors and breast cancer risk factors. Absolute risk reductions (ARR) were calculated based on Surveillance, Epidemiology, and End Results incidence rates. Results We showed that compared with women at low genetic risk or low MD, those with higher genetic risk scores or high MD had greater ARRs for breast cancer as circulating carotenoid levels increase (additive P-interaction = 0.05). Among women with a high polygenic risk score, those in the highest quartile of circulating carotenoids had a significant ARR (28.6%; 95% CI, 14.8–42.1%) compared to those in the lowest quartile of carotenoids. For women with a high percentage MD (≥50%), circulating carotenoids were associated with a 37.1% ARR (95% CI, 21.7–52.1%) when comparing the highest to the lowest quartiles of circulating carotenoids. Conclusions The inverse associations between circulating carotenoids and breast cancer risk appeared to be more pronounced in high-risk women, as defined by germline genetic makeup or MD.

scholarly journals Plasma concentration of brominated flame retardants and postmenopausal breast cancer risk: a nested case-control study in the French E3N cohort

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Francesca Romana Mancini ◽  
German Cano-Sancho ◽  
Oceane Mohamed ◽  
Iris Cervenka ◽  
Hanane Omichessan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Plasma Concentration ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Flame Retardants ◽  
Case Control Study ◽  
Postmenopausal Breast Cancer ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

scholarly journals Serum enterolactone concentration is not associated with breast cancer risk in a nested case-control study

2003 ◽  
Vol 108 (2) ◽  
pp. 277-280 ◽  
Author(s):  
Annamari Kilkkinen ◽  
Jarmo Virtamo ◽  
Erkki Vartiainen ◽  
Risto Sankila ◽  
Mikko J. Virtanen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

Mammographic breast density and breast cancer risk in a Mediterranean population: a nested case–control study in the EPIC Florence cohort

2017 ◽  
Vol 164 (2) ◽  
pp. 467-473 ◽  
Author(s):  
Giovanna Masala ◽  
Daniela Ambrogetti ◽  
Melania Assedi ◽  
Benedetta Bendinelli ◽  
Saverio Caini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Density ◽  
Case Control Study ◽  
Case Control ◽  
Mammographic Breast Density ◽  
Mediterranean Population ◽  
Nested Case Control ◽  
Control Study
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