scholarly journals Does mitochondrial DNA evolution in metazoa drive the origin of new mitochondrial proteins?

IUBMB Life ◽  
2018 ◽  
Vol 70 (12) ◽  
pp. 1240-1250 ◽  
Author(s):  
S. L. van Esveld ◽  
M. A. Huynen
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Proteins ◽  
Dna Evolution

SV40-transformed hamster cells resistant to 100–250 microgram/ml of ethidium bromide

1978 ◽  
Vol 33 (1) ◽  
pp. 157-169
Author(s):  
G. Wolf ◽  
L. Tejmar ◽  
S. Borell ◽  
W. Klietman
Keyword(s):  
Mitochondrial Dna ◽  
Cell Lines ◽  
Ethidium Bromide ◽  
Gel Electrophoresis ◽  
Mitochondrial Proteins ◽  
Wild Type ◽  
Mitochondrial Ultrastructure ◽  
Gold Hamsters ◽  
Resistant Cells

SV40-transformed hamster cells were selected for resistance to ethidium bromide (EB). Several cell lines were established, which grew in the presence of up to 250 microgram/ml EB. The EB resistance is genetically stable. The cloned resistant cells show no difference in morphology, with the exception of the mitochondrial ultrastructure, which exhibits condensed cristae formation. The tumorigenicity of these cells in Syrian gold hamsters is considerably reduced. Incorporation of radioactive labelled thymidine into mitochondrial DNA is not influenced by the presence of the drug. Gel electrophoresis with mitochondrial proteins from wild-type and resistant cells reveals significantly different patterns. The mechanism of EB resistance is discussed.

Localization of genes for variant forms of mitochondrial proteins on mitochondrial DNA of Saccharomyces cerevisiae

1977 ◽  
Vol 115 (4) ◽  
pp. 675-694 ◽  
Author(s):  
P.S. Perlman ◽  
M.G. Douglas ◽  
R.L. Strausberg ◽  
R.A. Butow
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Mitochondrial Dna ◽  
Mitochondrial Proteins

Mitochondrial DNA evolution in primates: Transition rate has been extremely low in the lemur

1990 ◽  
Vol 31 (2) ◽  
pp. 113-121 ◽  
Author(s):  
Masami Hasegawa ◽  
Hirohisa Kishino ◽  
Kenji Hayasaka ◽  
Satoshi Horai
Keyword(s):  
Mitochondrial Dna ◽  
Transition Rate ◽  
Dna Evolution

scholarly journals Infection of New- and Old-World Aedes albopictus (Diptera: Culicidae) by the Intracellular Parasite Wolbachia: Implications for Host Mitochondrial DNA Evolution

2003 ◽  
Vol 40 (3) ◽  
pp. 356-360 ◽  
Author(s):  
Peter Armbruster ◽  
William E. Damsky ◽  
Rosanna Giordano ◽  
Josephine Birungi ◽  
Leonard E. Munstermann ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Aedes Albopictus ◽  
Intracellular Parasite ◽  
Old World ◽  
Dna Evolution

Mitochondrial DNA evolution and population history of the Tenerife skinkChalcides viridanus

2000 ◽  
Vol 9 (8) ◽  
pp. 1061-1067 ◽  
Author(s):  
R. P. Brown ◽  
R. Campos-Delgado ◽  
J. Pestano
Keyword(s):  
Mitochondrial Dna ◽  
Population History ◽  
Dna Evolution ◽  
History Of

scholarly journals Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA.

1997 ◽  
Vol 8 (7) ◽  
pp. 1233-1242 ◽  
Author(s):  
J Nunnari ◽  
W F Marshall ◽  
A Straight ◽  
A Murray ◽  
J W Sedat ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Fluorescence Microscopy ◽  
Fluorescent Dyes ◽  
Mitochondrial Protein ◽  
Mitochondrial Proteins ◽  
Dimensional Structure ◽  
Wide Field ◽  
Protein Markers ◽  
Protein Marker ◽  
Mitochondrial Transmission

To gain insight into the process of mitochondrial transmission in yeast, we directly labeled mitochondrial proteins and mitochondrial DNA (mtDNA) and observed their fate after the fusion of two cells. To this end, mitochondrial proteins in haploid cells of opposite mating type were labeled with different fluorescent dyes and observed by fluorescence microscopy after mating of the cells. Parental mitochondrial protein markers rapidly redistributed and colocalized throughout zygotes, indicating that during mating, parental mitochondria fuse and their protein contents intermix, consistent with results previously obtained with a single parentally derived protein marker. Analysis of the three-dimensional structure and dynamics of mitochondria in living cells with wide-field fluorescence microscopy indicated that mitochondria form a single dynamic network, whose continuity is maintained by a balanced frequency of fission and fusion events. Thus, the complete mixing of mitochondrial proteins can be explained by the formation of one continuous mitochondrial compartment after mating. In marked contrast to the mixing of parental mitochondrial proteins after fusion, mtDNA (labeled with the thymidine analogue 5-bromodeoxyuridine) remained distinctly localized to one half of the zygotic cell. This observation provides a direct explanation for the genetically observed nonrandom patterns of mtDNA transmission. We propose that anchoring of mtDNA within the organelle is linked to an active segregation mechanism that ensures accurate inheritance of mtDNA along with the organelle.

scholarly journals Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.

1989 ◽  
Vol 86 (16) ◽  
pp. 6196-6200 ◽  
Author(s):  
T. D. Kocher ◽  
W. K. Thomas ◽  
A. Meyer ◽  
S. V. Edwards ◽  
S. Paabo ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Dna Evolution
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