scholarly journals Negative control of liver-specific gene expression: cloned human retinol-binding protein gene is repressed in HeLa cells.

1987 ◽  
Vol 6 (3) ◽  
pp. 631-636 ◽  
Author(s):  
V. Colantuoni ◽  
A. Pirozzi ◽  
C. Blance ◽  
R. Cortese
Keyword(s):  
Gene Expression ◽  
Hela Cells ◽  
Protein Gene ◽  
Binding Protein ◽  
Negative Control ◽  
Retinol Binding Protein ◽  
Specific Gene ◽  
Specific Gene Expression ◽  
Binding Protein Gene

scholarly journals Retinol-Binding Protein Gene Expression in Cyclic and Pregnant Endometrium of Pigs, Sheep, and Cattle1

1993 ◽  
Vol 49 (5) ◽  
pp. 1066-1073 ◽  
Author(s):  
Jacob P. Harney ◽  
Troy L. Ott ◽  
Rodney D. Geisert ◽  
Fuller W. Bazer
Keyword(s):  
Gene Expression ◽  
Protein Gene ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Binding Protein Gene

scholarly journals GA-Binding Protein Is Dispensable for Neuromuscular Synapse Formation and Synapse-Specific Gene Expression

2007 ◽  
Vol 27 (13) ◽  
pp. 5040-5046 ◽  
Author(s):  
Alexander Jaworski ◽  
Cynthia L. Smith ◽  
Steven J. Burden
Keyword(s):  
Gene Expression ◽  
Synapse Formation ◽  
Binding Protein ◽  
Neuromuscular Synapse ◽  
Specific Gene ◽  
Promoter Regions ◽  
Specific Gene Expression ◽  
Muscle Gene Expression ◽  
Synaptic Region ◽  
Ga Binding Protein

ABSTRACT The mRNAs encoding postsynaptic components at the neuromuscular junction are concentrated in the synaptic region of muscle fibers. Accumulation of these RNAs in the synaptic region is mediated, at least in part, by selective transcription of the corresponding genes in synaptic myofiber nuclei. The transcriptional mechanisms that are responsible for synapse-specific gene expression are largely unknown, but an Ets site in the promoter regions of acetylcholine receptor (AChR) subunit genes and other “synaptic” genes is required for synapse-specific transcription. The Ets domain transcription factor GA-binding protein (GABP) has been implicated to mediate synapse-specific gene expression. Inactivation of GABPα, the DNA-binding subunit of GABP, leads to early embryonic lethality, preventing analysis of synapse formation in gabpα mutant mice. To study the role of GABP at neuromuscular synapses, we conditionally inactivated gabpα in skeletal muscle and studied synaptic differentiation and muscle gene expression. Although expression of rb, a target of GABP, is elevated in muscle tissue deficient in GABPα, clustering of synaptic AChRs at synapses and synapse-specific gene expression are normal in these mice. These data indicate that GABP is dispensable for synapse-specific transcription and maintenance of normal AChR expression at synapses.

Tissue-Specific Regulation of Renin-Binding Protein Gene Expression in Rats1

1992 ◽  
Vol 112 (2) ◽  
pp. 175-182 ◽  
Author(s):  
Masazumi Tada ◽  
Saori Takahashi ◽  
Motoshige Miyano ◽  
Yoshihiro Miyake
Keyword(s):  
Gene Expression ◽  
Protein Gene ◽  
Binding Protein ◽  
Tissue Specific ◽  
Binding Protein Gene ◽  
Specific Regulation
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