Bone regeneration using β‐tricalcium phosphate (β‐TCP) block with interconnected pores made by setting reaction of β‐TCP granules

2019 ◽  
Vol 108 (3) ◽  
pp. 625-632
Author(s):  
Tansza S. Putri ◽  
Koichiro Hayashi ◽  
Kunio Ishikawa
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Setting Reaction ◽  
Interconnected Pores

Apatite Foam Fabrication Based on Hydrothermal Reaction of α-Tricalcium Phosphate Foam

2007 ◽  
Vol 361-363 ◽  
pp. 319-322 ◽  
Author(s):  
Ishikawa Kunio ◽  
Satoshi Karashima ◽  
Akari Takeuchi ◽  
Shigeki Matsuya
Keyword(s):  
Pore Size ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Tricalcium Phosphate ◽  
Hydrothermal Reaction ◽  
Bone Substitutes ◽  
Tissue Response ◽  
Bone Tissue Regeneration ◽  
Setting Reaction ◽  
Interconnected Pores

Apatite foam (AP foam) is an ideal material for bone substitutes and scaffolds in bone tissue regeneration. This is because its highly porous interconnected pores provide the space for cell growth and tissue penetration, and that its composition induces excellent tissue response and good osteoconductivity. In the present study, the feasibility of apatite foam fabrication was evaluated based on so-called dissolution-reprecipitation reaction of α-tricalcium phosphate (α-TCP) foam granules. When α-TCP foam granules were placed in water at 37°C for 24h, no reaction was observed. However, α-TCP foam set to form AP foam when treated hydrothermally at 200°C. The network of fully interconnected pores was retained, and porosity was as high as 82%. Pore size ranged from 50 to 300 0m with average pore size at 160 0m. Compressive strength was 207 kPa. Although no setting reaction was observed at 37°C, setting reaction caused by hydrothermal treatment of α-TCP foam granules at 200°C allows AP foam of any shape to be fabricated. Therefore, this method was suggested to be useful for the fabrication of bone substitutes and the scaffold in bone tissue regeneration.

Melatonin decorated 3D-printed beta-tricalcium phosphate scaffolds promoting bone regeneration in a rat calvarial defect model

2019 ◽  
Vol 7 (20) ◽  
pp. 3250-3259 ◽  
Author(s):  
Yali Miao ◽  
Yunhua Chen ◽  
Xiao Liu ◽  
Jingjing Diao ◽  
Naru Zhao ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Calvarial Defect ◽  
Defect Model ◽  
Beta Tricalcium Phosphate ◽  
3D Printed ◽  
Rat Calvarial Defect

3D-printed β-TCP scaffolds decorated with melatonin via dopamine mussel-inspired chemistry enhance the osteogenesis and in vivo bone regeneration.

scholarly journals Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration: Physiochemical and microcomputer tomographical characterization

2017 ◽  
Vol 106 (3) ◽  
pp. 822-828 ◽  
Author(s):  
Timothy E. L. Douglas ◽  
Josefien Schietse ◽  
Aneta Zima ◽  
Svetlana Gorodzha ◽  
Bogdan V. Parakhonskiy ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Injectable Hydrogel

Effects of porous beta-tricalcium phosphate-based ceramics used as an E. coli-derived rhBMP-2 carrier for bone regeneration

2013 ◽  
Vol 24 (9) ◽  
pp. 2117-2127 ◽  
Author(s):  
Jae Hyup Lee ◽  
Mi Young Ryu ◽  
Hae-Ri Baek ◽  
Kyung Mee Lee ◽  
Jun-Hyuk Seo ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
E Coli ◽  
Beta Tricalcium Phosphate
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