Inhibited effect of anRGDpeptide hydrogel on the expression of β1‐integrin,FAK, and Akt in Tenon's capsule fibroblasts

2021 ◽  
Author(s):  
Baoji Chen ◽  
Ping Wu ◽  
Liang Liang ◽  
Chenchen Zhao ◽  
Zheng Wang ◽  
...  
Keyword(s):  
Β1 Integrin ◽  
Tenon’S Capsule ◽  
Tenon's Capsule

Comparison of Intravitreal versus Posterior Sub–Tenon’s Capsule Injection of Triamcinolone Acetonide for Diffuse Diabetic Macular Edema

Ophthalmology ◽  
2005 ◽  
Vol 112 (9) ◽  
pp. 1557-1563 ◽  
Author(s):  
José A. Cardillo ◽  
Luiz A.S. Melo ◽  
Rogério A. Costa ◽  
Mirian Skaf ◽  
Rubens Belfort ◽  
...  
Keyword(s):  
Macular Edema ◽  
Triamcinolone Acetonide ◽  
Diabetic Macular Edema ◽  
Tenon’S Capsule ◽  
Diffuse Diabetic Macular Edema ◽  
Tenon's Capsule

A sub-Tenon’s capsule injection of lidocaine induces extraocular muscle akinesia and mydriasis in dogs

2013 ◽  
Vol 196 (1) ◽  
pp. 103-108 ◽  
Author(s):  
J.S. Ahn ◽  
M.B. Jeong ◽  
Y.W. Park ◽  
Y.S.R. Lee ◽  
E.R. Lee ◽  
...  
Keyword(s):  
Extraocular Muscle ◽  
Tenon’S Capsule ◽  
Tenon's Capsule

Effects of varying 5-fluorouracil exposure duration on Tenon's capsule fibroblasts

2001 ◽  
Vol 29 (4) ◽  
pp. 248-252 ◽  
Author(s):  
Michael B Merriman ◽  
Justin S Mora ◽  
Brent W Beaumont ◽  
Mervyn J Merrilees
Keyword(s):  
Exposure Duration ◽  
Tenon’S Capsule ◽  
Tenon's Capsule

scholarly journals Effect of Lignocaine Concentration on Human Fibroblasts Growth in Eyes Undergoing Trabeculectomy: An in vitro Study

2018 ◽  
Vol 3 (3) ◽  
pp. 1-10 ◽  
Author(s):  
Madhuravasal Krishnan Janani ◽  
Venkatakrishnan Jaichandran ◽  
Hajib Narahari Rao Madhavan ◽  
Lingam Vijaya ◽  
Ronnie Jacob George ◽  
...  
Keyword(s):  
Culture Medium ◽  
In Vitro Model ◽  
Morphological Changes ◽  
Human Fibroblasts ◽  
Annexin V ◽  
In Vitro Study ◽  
Tenon’S Capsule ◽  
Tenon's Capsule ◽  
Vitro Model

Purpose: To evaluate the effect of lignocaine on growth and apoptosis indication of primary human Tenon’s capsule fibroblast (HTFs) in an in vitro model. Patients and Methods: Tenon’s capsule tissue obtained from patients undergoing trabeculectomy were grown in cell culture medium. The effect of different concentrations of lignocaine (0.5, 1.0, 1.5, and 2%) on the morphology and growth of the fibroblasts was studied using microscopy, cell viability, and proliferation assay, and apoptosis was detected using the FITC Annexin V Apoptosis Kit. Results: Morphological changes similar to those of apoptotic cells, including cytoplasmic vacuolation, shrinkage, and rounding were visualized in the cells treated with concentrations greater than 1.0% (i.e., 1.5, 2.0%). Though proliferation inhibition was found with all four concentrations (0.5–2.0%), the viability of cells decreased from 1.0% lignocaine. Conclusion: 0.5% lignocaine prevents proliferation of fibroblasts without causing apoptosis in vitro.

scholarly journals Preservation of the Tenon’s capsule and Sub-Tenon’s space after the autologous limbal-conjunctival transplantation in pterygium surgery

2021 ◽  
Author(s):  
FERNANDA Santos VIDAL ◽  
Sebastião Cronemberger ◽  
José Aloísio Massote
Keyword(s):  
Anterior Segment ◽  
Preoperative Period ◽  
Secondary Intention ◽  
Tenon’S Capsule ◽  
Postoperative Control ◽  
Significant Difference ◽  
Donor Area ◽  
Tenon's Capsule ◽  
Pterygium Surgery ◽  
The Mean

Abstract Background No previous studies have evaluated the scarring of the conjunctiva and Tenon’s capsule (TC) separately when only the conjunctiva is removed, and TC is preserved in the upper part of the bulb: the site designated for trabeculectomy. Thus, this cohort interventional study aims to investigate the scarring of the donor area after autologous limbal-conjunctival transplantation (ALCT) using anterior segment optical coherence tomography (AS-OCT). Methods Twenty-three eyes with pterygium were submitted to resection and local reconstruction with ALCT. AS-OCT images obtained from each eye preoperatively served as postoperative control. ALCT was removed superiorly with preservation of TC. The cure of this donor area occurred by secondary intention. AS-OCT was performed preoperatively and 30 and 180 days postoperatively in the donor area, measuring the thickness of the conjunctiva (epithelium and stroma) and TC. The sub-Tenon’s space (STS) was clinically assessed. Results The mean thickness of the conjunctival epithelium was 48.04 ± 11.37µm in the preoperative period and 51.87±15.04µm 180 days after surgery, without statistically significant difference (P=0.282). A statistically significant increase (P=0.005) in the mean thickness of the conjunctival stroma, from 85.35±23.10µm in the preoperative period to 101.61±20.19µm 180 days after surgery was found. TC had no significant changes, slightly increasing from 117.13±24.26µm preoperatively to 118.09±19.24µm (P=0.808) 180 days after surgery. STS was found in 19 (82%) eyes 180 days after surgery. Conclusions Following ALCT with TC preservation, scarring took place in the conjunctiva, epithelium, and stroma. The TC and the STS were preserved not showing any significant changes.

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