scholarly journals Association of Dietary Niacin Intake With Incident Hip Fracture, BMD, and Body Composition: The Cardiovascular Health Study

2019 ◽  
Vol 34 (4) ◽  
pp. 643-652 ◽  
Author(s):  
Laura D Carbone ◽  
Petra Bůžková ◽  
Howard A Fink ◽  
Mattie Raiford ◽  
Brian Le ◽  
...  
Keyword(s):  
Body Composition ◽  
Hip Fracture ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study

scholarly journals The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study

2019 ◽  
Vol 105 (2) ◽  
pp. 161-172 ◽  
Author(s):  
Brian Le ◽  
Petra Bůžková ◽  
John A. Robbins ◽  
Howard A. Fink ◽  
Mattie Raiford ◽  
...  
Keyword(s):  
Amino Acids ◽  
Body Composition ◽  
Hip Fracture ◽  
Cardiovascular Health ◽  
Aromatic Amino Acids ◽  
Health Study ◽  
Cardiovascular Health Study

scholarly journals Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study

2017 ◽  
Vol 28 (5) ◽  
pp. 1631-1640 ◽  
Author(s):  
L. D. Carbone ◽  
P. Bůžková ◽  
H. A. Fink ◽  
J. A. Robbins ◽  
M. Bethel ◽  
...  
Keyword(s):  
Body Composition ◽  
Hip Fracture ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study

scholarly journals Associations of body composition with incident dementia in older adults: Cardiovascular Health Study‐Cognition Study

2020 ◽  
Vol 16 (10) ◽  
pp. 1402-1411
Author(s):  
Chendi Cui ◽  
Rachel H. Mackey ◽  
C. Elizabeth Shaaban ◽  
Lewis H. Kuller ◽  
Oscar L. Lopez ◽  
...  
Keyword(s):  
Older Adults ◽  
Body Composition ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Incident Dementia

scholarly journals Biochemical markers of bone turnover and risk of incident hip fracture in older women: the Cardiovascular Health Study

2019 ◽  
Vol 30 (9) ◽  
pp. 1755-1765
Author(s):  
D. Massera ◽  
S. Xu ◽  
M. D. Walker ◽  
R. J. Valderrábano ◽  
K. J. Mukamal ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Bone Turnover ◽  
Older Women ◽  
Biochemical Markers ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Markers Of Bone Turnover

scholarly journals Potential Explanatory Factors for Higher Incident Hip Fracture Risk in Older Diabetic Adults

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Elsa S. Strotmeyer ◽  
Aruna Kamineni ◽  
Jane A. Cauley ◽  
John A. Robbins ◽  
Linda F. Fried ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Fracture Risk ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Hip Fracture Risk ◽  
Explanatory Factors ◽  
Artery Disease ◽  
Study Participants

Type 2 diabetes is associated with higher fracture risk. Diabetes-related conditions may account for this risk. Cardiovascular Health Study participants (N=5641; 42.0% men; 15.5% black; 72.8±5.6 years) were followed 10.9±4.6 years. Diabetes was defined as hypoglycemic medication use or fasting glucose (FG)≥126 mg/dL. Peripheral artery disease (PAD) was defined as ankle-arm index <0.9. Incident hip fractures were from medical records. Crude hip fracture rates (/1000 person-years) were higher for diabetic vs. non-diabetic participants with BMI <25 (13.6, 95% CI: 8.9–20.2 versus 11.4, 95% CI: 10.1–12.9) and BMI≥25 to <30 (8.3, 95% CI: 5.7–11.9 versus 6.6, 95% CI: 5.6–7.7), but similar for BMI≥30. Adjusting for BMI, sex, race, and age, diabetes was related to fractures (HR = 1.34; 95% CI: 1.01–1.78). PAD (HR = 1.25 (95% CI: 0.92–1.57)) and longer walk time (HR = 1.07 (95% CI: 1.04–1.10)) modified the fracture risk in diabetes (HR = 1.17 (95% CI: 0.87–1.57)). Diabetes was associated with higher hip fracture risk after adjusting for BMI though this association was modified by diabetes-related conditions.

scholarly journals Subclinical Hypothyroidism, Weight Change, and Body Composition in the Elderly: The Cardiovascular Health Study

2014 ◽  
Vol 99 (4) ◽  
pp. 1220-1226 ◽  
Author(s):  
Margaret C. Garin ◽  
Alice M. Arnold ◽  
Jennifer S. Lee ◽  
Russell P. Tracy ◽  
Anne R. Cappola
Keyword(s):  
Body Composition ◽  
Weight Change ◽  
Subclinical Hypothyroidism ◽  
Cardiovascular Health ◽  
The Elderly ◽  
Health Study ◽  
Cardiovascular Health Study

scholarly journals Fibroblast Growth Factor 23, Bone Mineral Density, and Risk of Hip Fracture Among Older Adults: The Cardiovascular Health Study

2013 ◽  
Vol 98 (8) ◽  
pp. 3323-3331 ◽  
Author(s):  
Anna Jovanovich ◽  
Petra Bùžková ◽  
Michel Chonchol ◽  
John Robbins ◽  
Howard A. Fink ◽  
...  
Keyword(s):  
Older Adults ◽  
Hip Fracture ◽  
Lumbar Spine ◽  
Cardiovascular Health ◽  
Fibroblast Growth Factor 23 ◽  
Community Dwelling ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Mineral Density ◽  
Total Hip

Context: Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that also inhibits calcitriol synthesis. Objective: Our objective was to evaluate the relationships of plasma FGF23 concentrations with bone mineral density (BMD) and hip fracture in community-dwelling older adults. Design and Setting: Linear regression and Cox proportional hazard models were used to examine the associations of plasma FGF23 concentrations with BMD and incident hip fracture, respectively. Analyses were also stratified by chronic kidney disease. Participants: Participants included 2008 women and 1329 men ≥65 years from the 1996 to 1997 Cardiovascular Health Study visit. Main Outcome Measures: Dual x-ray absorptiometry measured total hip (TH) and lumbar spine (LS) BMD in 1291 participants. Hip fracture incidence was assessed prospectively through June 30, 2008 by hospitalization records in all participants. Results: Women had higher plasma FGF23 concentrations than men (75 [56–107] vs 66 [interquartile range = 52–92] relative units/mL; P &lt; .001). After adjustment, higher FGF23 concentrations were associated with greater total hip and lumbar spine BMD in men only (β per doubling of FGF23 = 0.02, with 95% confidence interval [CI] = 0.001–0.04 g/cm2, and 0.03 with 95% CI = 0.01–0.06 g/cm2). During 9.6 ± 5.1–11.0 years of follow-up, 328 hip fractures occurred. Higher FGF23 concentrations were not associated with hip fracture risk in women or men (adjusted hazard ratio = 0.95, with 95% CI = 0.78–1.15, and 1.09 with 95% CI = 0.82–1.46 per doubling of FGF23). Results did not differ by chronic kidney disease status (P &gt; .4 for interactions). Conclusions: In this large prospective cohort of community-dwelling older adults, higher FGF23 concentrations were weakly associated with greater lumbar spine and total hip BMD but not with hip fracture risk.

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