Modulation of beta-adrenergic response in rat brain astrocytes by serum and hormones

1985 ◽  
Vol 122 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Doris K. Wu ◽  
Richard S. Morrison ◽  
Jean de Vellis
Keyword(s):  
Rat Brain ◽  
Beta Adrenergic ◽  
Adrenergic Response

Serotonin enhances the β-adrenergic response in rat brain cortical slices

1992 ◽  
Vol 225 (3) ◽  
pp. 273-274 ◽  
Author(s):  
Didier Morin ◽  
Rosa Sapena ◽  
Roland Zini ◽  
Jean-Paul Tillement
Keyword(s):  
Rat Brain ◽  
Adrenergic Response ◽  
Cortical Slices

Decreased beta-adrenergic receptors in rat brain after chronic administration of the selective serotonin uptake inhibitor fluoxetine

1988 ◽  
Vol 94 (1) ◽  
pp. 141-143 ◽  
Author(s):  
William F. Byerley ◽  
Elizabeth J. McConnell ◽  
R. Tyler McCabe ◽  
Ted M. Dawson ◽  
Bernard I. Grosser ◽  
...  
Keyword(s):  
Rat Brain ◽  
Adrenergic Receptors ◽  
Chronic Administration ◽  
Serotonin Uptake ◽  
Selective Serotonin ◽  
Beta Adrenergic Receptors ◽  
Beta Adrenergic ◽  
Uptake Inhibitor ◽  
Serotonin Uptake Inhibitor

PDK-1 Plays Essential Roles in the Regulation of Cell Size, Beta-adrenergic Response and Cell Survival in the Heart

2006 ◽  
Vol 12 (8) ◽  
pp. S159
Author(s):  
Kaoru Ito ◽  
Hiroshi Akazawa ◽  
Masaji Tamagawa ◽  
Norio Suda ◽  
Wataru Ogawa ◽  
...  
Keyword(s):  
Cell Survival ◽  
Cell Size ◽  
Beta Adrenergic ◽  
Adrenergic Response

scholarly journals Beta-Adrenergic Response in Human HCM Myocardium: Effects of Ranolazine

2014 ◽  
Vol 106 (2) ◽  
pp. 347a
Author(s):  
Cecilia Ferrantini ◽  
Raffaele Coppini ◽  
Benedetta Tosi ◽  
Josè Manuel Pioner ◽  
Laura Sartiani ◽  
...  
Keyword(s):  
Beta Adrenergic ◽  
Adrenergic Response

Membrane-delimited stimulation of heart cell calcium current by beta-adrenergic signal-transducing Gs protein

1990 ◽  
Vol 259 (1) ◽  
pp. H264-H267 ◽  
Author(s):  
S. Pelzer ◽  
Y. M. Shuba ◽  
T. Asai ◽  
J. Codina ◽  
L. Birnbaumer ◽  
...  
Keyword(s):  
Calcium Current ◽  
Receptor Activation ◽  
Heart Cell ◽  
Ca Channels ◽  
Beta Adrenergic ◽  
Physiological Regulation ◽  
Beta Receptor ◽  
Adrenergic Response ◽  
Gs Protein ◽  
Stimulation Of

A severalfold increase in calcium current (ICa) is a signal feature of the maximal beta-adrenergic response of the heart. It is generally ascribed to enhanced adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphorylation of calcium (Ca) channels after beta-receptor activation of the guanosine nucleotide-binding (G) protein Gs, and Gs activation of the adenylyl cyclase cascade. We blocked phosphorylation pathways in guinea pig cardiomyocytes to unmask other possible ICa-stimulatory modes. In blocked cells, ICa increased by approximately 50% during 1) beta-receptor activation of Gs, 2) intracellular activation of Gs, and 3) intracellular application of preactivated Gs, We conclude that fast, membrane-delimited Gs modulation participates in the physiological regulation of cardiac ICa.

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