Reactive extraction of itaconic acid using tri-n-butyl phosphate and aliquat 336 in sunflower oil as a non-toxic diluent

Abstract Biomass is an attractive target in process development for the emerging renewable resources based bio-refinery industry. Due to the ample range of application of acrylic acid, its production through bio-route received more awareness in scientific fraternity. In this view, an attempted was made to study the reactive extraction of acrylic acid with aliquat 336 in rice bran oil. Moreover, Box-Behnken matrix was employed to corroborate the effects of process variables viz. concentration of acrylic acid [CAA]aq, concentration of aliquat 336 [CR4N+Cl], and temperature on the extraction efficiency (η%). In physical extraction, average extraction efficiency was found in the order as: 43.55 > 35.36 > 29.14 at 303 K, 323 K, and 343 K respectively in rice bran oil. The correlation coefficient, R2 = 0.988 % indicates the appropriateness of proposed model to predict the extraction efficiency in terms of independent variables, and the predicted values were found in close agreement with that of experimental results. Further, R2(Pred) = 0.806 is in reasonable agreement with the R2(Adj) = 0.972. The optimum conditions for extraction of acrylic acid using aliquat 336 as an extractant in rice bran oil are [CAA]aq = 0.0.5 (mol/kg); [CR4N+Cl] = 1.98 (mol/kg); temperature = 323 K and the model predicted extraction efficiency 77.5 % was found to be an excellent fit with the experimental value 75 %. Further, number of theoretical stages was found to be 3 and S/F ratio 0.247.

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Study on the Biocompatible Solvent Systems for the Reactive Extraction of Itaconic Acid

Journal of Chemical & Engineering Data ◽

10.1021/acs.jced.9b00342 ◽

2019 ◽

Vol 64 (10) ◽

pp. 4280-4285 ◽

Cited By ~ 1

Author(s):

Dipaloy Datta ◽

Neha Chomal ◽

Hasan Uslu ◽

Sushil Kumar

Keyword(s):

Itaconic Acid ◽

Reactive Extraction ◽

Solvent Systems

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Development of reactive extraction systems for itaconic acid: a step towards in situ product recovery for itaconic acid fermentation

RSC Advances ◽

10.1039/c4ra06612j ◽

2014 ◽

Vol 4 (85) ◽

pp. 45029-45039 ◽

Cited By ~ 23

Author(s):

Guneet Kaur ◽

Kathy Elst

Keyword(s):

Process Optimization ◽

Itaconic Acid ◽

Acid Production ◽

Product Recovery ◽

Reactive Extraction ◽

Acid Fermentation ◽

In Situ Product Recovery ◽

Product Separation ◽

Important Means

Process optimization by integration of bioconversion with product separation and recovery i.e. in situ product recovery (ISPR) is an important means to develop a sustainable and petrochemical-competitive biotechnological method for itaconic acid production.

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REACTIVE EXTRACTION OF 7-AMINOCEPHALOSPORANIC ACID WITH ALIQUAT-336: EQUILIBRIUM AND KINETICS

Chemical Engineering Communications ◽

10.1080/00986440008912187 ◽

2000 ◽

Vol 179 (1) ◽

pp. 15-34 ◽

Cited By ~ 3

Author(s):

MADAN M. BORA ◽

NARENDRA N. DUTTA ◽

KRISHNA G. BHATTACHARYA

Keyword(s):

Reactive Extraction ◽

Aliquat 336 ◽

Equilibrium And Kinetics

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Equilibrium and Kinetics of Reactive Extraction of Propionic Acid Using Aliquat 336 and Tri-n-Butyl Phosphate in n-Hexanol

International Journal of Chemical Reactor Engineering ◽

10.2202/1542-6580.1850 ◽

2009 ◽

Vol 7 (1) ◽

Cited By ~ 2

Author(s):

Dr. Kailas L. Wasewar ◽

Amit Keshav ◽

Shri Chand

Keyword(s):

Propionic Acid ◽

Acid Concentration ◽

Fermentation Broth ◽

Reactive Extraction ◽

Acid Extraction ◽

Aliquat 336 ◽

Pseudo First Order Reaction ◽

First Order ◽

Pharmaceutical Industries ◽

Kinetics Of

Recovery of propionic acid from different sources, like aqueous streams or from fermentation broth, is important in view of its wide usage in food, chemical and pharmaceutical industries. Reactive extraction is an emerging separation technique having numerous advantages like high selectivity and recovery. Effect of acid concentration, extractant concentration, pH, temperature and kinetics are the important steps in the reactive extraction. Equilibrium of propionic acid extraction using tri-n-butyl phosphate (TBP) and Aliquat 336 in n-hexanol respectively was carried out to find the better extractant out of the two for extraction of propionic acid. Aliquat 336 was found to be better than TBP with Ks = 2.2119 m3/kmol, thus indicating good complexation between it and the acid. The kinetics of extraction of the acid using Aliquat 336 in a stirred cell was investigated. The reaction was found to be first order in acid concentration and zero order in Aliquat 336 concentration. The reaction was found to be fast pseudo first order reaction occurring in the diffusion film and was found to be independent of hydrodynamics conditions. Rate constant was evaluated to be 163.398 1/s.

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Equilibrium & kinetic studies of reactive extraction of trans-aconitic acid using sunflower oil with tri-n-octylamine

International Journal of Chemical Reactor Engineering ◽

10.1515/ijcre-2021-0107 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Rajesh Nimmakayala ◽

Dharm Pal ◽

Dhananjay Singh ◽

Abhinesh Kumar Prajapati

Keyword(s):

Sunflower Oil ◽

Fermentation Broth ◽

Kinetic Studies ◽

Reactive Extraction ◽

Equilibrium Studies ◽

Aconitic Acid ◽

Equilibrium And Kinetics ◽

Loading Ratio ◽

Stirred Cell ◽

Complex Formations

Abstract In order to design an efficient extraction system for the separation of biochemically produced trans-aconitic acid (TAH) from fermentation broth; equilibrium and kinetics of reactive extraction of TAH from aqueous solutions was investigated using tri-n-octylamine (TOA) as an extractant and sunflower oil as a diluent. Through the equilibrium studies stoichiometry (acid, extractant) of complex formations was determined with the help of loading ratio. Formation of (1, 1), (2, 1), & (3, 1) stoichiometry complexes were observed having complexation constants values 179.73 kmol−1 m3, 9512.58 kmol−2 m6, and 614,407.02 kmol−3 m9, respectively. Kinetics experiments were performed in Lewis type stirred cell and results confirmed that reaction between TAH and TOA in sunflower oil fall in regime 1, i.e. slow reaction occurring in bulk organic phase. The overall order of reaction is pseudo first order with rate constant (K mn ) 1.78 × 10−5 (kmol m−3)−0.71 s−1 and physical mass transfer coefficient (K l ) 4.22 × 10−5 m s−1.

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