scholarly journals High prevalence of non‐alcoholic fatty liver disease among healthy male blood donors of urban India

JGH Open ◽  
2019 ◽  
Vol 3 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Ajay Duseja ◽  
Shaneez Najmy ◽  
Suchet Sachdev ◽  
Arnab Pal ◽  
Rati Ram Sharma ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Blood Donors ◽  
Healthy Male ◽  
Alcoholic Fatty Liver ◽  
High Prevalence ◽  
Urban India ◽  
Alcoholic Fatty Liver Disease

scholarly journals Non-Alcoholic Fatty Liver Disease: How to Avoid Mistakes in Patient’s Curation

2021 ◽  
Vol 17 (4) ◽  
pp. 62-67
Author(s):  
M.A. Livzan ◽  
◽  
T.S. Krolevets ◽  
T.V. Kostoglod ◽  
A.V. Kostoglod
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Metabolic Profile ◽  
Potential Danger ◽  
Alcoholic Fatty Liver ◽  
Priority Task ◽  
High Prevalence ◽  
Common Problems ◽  
Alcoholic Fatty Liver Disease

The high prevalence of non-alcoholic fatty liver disease and its association with diseases of the metabolic profile causes the interest of doctors of various specialties in the management of patients with this pathology. Due to the accumulation of data on risk factors and disease progression, approaches and attitudes about previously harmless pathology have evolved to understand its potential danger. The formation of the correct approach to the management of patients with non-alcoholic fatty liver disease is a priority task. In this publication, we have analyzed and systematized data from literature concerning the most common problems (mistakes) in the curation of patients with non-alcoholic fatty liver disease.

scholarly journals Features of the course of gallstone disease in patients with non-alcoholic fatty liver disease

2020 ◽  
Vol 92 (2) ◽  
pp. 48-54 ◽  
Author(s):  
N. A. Cherkashchenko ◽  
M. A. Livzan ◽  
T. S. Krolevets
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Gallstone Disease ◽  
Alcoholic Fatty Liver ◽  
High Prevalence ◽  
Group 3 ◽  
Alcoholic Fatty Liver Disease

Aim.To update information about comorbidity of non-alcoholic fatty liver disease (NAFLD) and gallstones disease (GD), evaluation of clinical and laboratory data, including insulin, leptin and adiponectin in individuals with NAFLD in combination with GD. Materials and methods.According to the design, we conducted an open comparative study of 169 patients with NAFLD. The following comparison groups were formed: group 1 (n=95) patients with NAFLD without GD, group 2 (n=35) patients with NAFLD and GD and group 3 (n=39) patients with NAFLD, GD and previous cholecystectomy. Results.A high prevalence of coronary heart disease was found in the group of patients with GD and cholecystectomy (2=6.198,p0.05); positive, statistically significant correlation relationships of cholelithiasis, cholecystectomy with ischemic heart disease (rs=0.172,p0.05 andrs=0.241,p0.05, respectively). There was a statistically significant decrease in total bilirubin and total protein in patients of group 3 (H=7.376,p0.03 and H=6.345,p0.04). The level of leptin is statistically significantly higher and positively interrelated with cholecystectomy (H=5.812,p0.05,rs=0.313,p0.05). Conclusion.Patients with NAFLD, GD and previous cholecystectomy have a high prevalence of coronary heart disease; the phenomenon of insulin and leptin resistance, high level of adiponectin were revealed in patients with NAFLD and gallstones; hyperleptinemia was observed among patients with NAFLD, GD after cholecystectomy.

Non-alcoholic fatty liver disease is associated with high prevalence of gastro-oesophageal reflux symptoms

2012 ◽  
Vol 44 (12) ◽  
pp. 1032-1036 ◽  
Author(s):  
Luca Miele ◽  
Giovanni Cammarota ◽  
Vittoria Vero ◽  
Simona Racco ◽  
Consuelo Cefalo ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Oesophageal Reflux ◽  
Alcoholic Fatty Liver ◽  
Reflux Symptoms ◽  
High Prevalence ◽  
Alcoholic Fatty Liver Disease

scholarly journals Features of the course of non-alcoholic fatty liver disease in HIV-infected individuals

2020 ◽  
Vol 47 (2) ◽  
pp. 66-71
Author(s):  
V. A. Akhmedov ◽  
N. F. Mamedova ◽  
A. V. Verbanov ◽  
O. V. Gaus ◽  
O. V. Gaus
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Steatosis ◽  
Experimental Studies ◽  
Rapid Progression ◽  
People Living With Hiv ◽  
Alcoholic Fatty Liver ◽  
High Prevalence ◽  
Alcoholic Fatty Liver Disease

This article reflects the course of non-alcoholic fatty liver disease (NAFLD) in HIV-infected individuals. It is noted that long-term antiretroviral therapy and the use of D-drugs can explain the high prevalence of steatosis in this category of patients. The results of experimental studies that demonstrate the direct effect of HIV on liver steatosis by infection of stellate liver cells, stimulation of abnormal expression of SREBP-1 and PPARγ are considered. The role of HIV-mediated microbial translocation as one of the triggers for the development of non-alcoholic steatohepatitis (NASH), which contributes to chronic inflammation due to an increase in the permeability of the intestinal barrier to bacterial products and endotoxins, is noted. Data are presented confirming the high prevalence of the abnormal distribution of fat and visceral obesity (components of lipodystrophy syndrome) in a cohort of HIV-infected individuals. There was a high prevalence of steatosis and steatohepatitis in HIV-infected patients with lipodystrophy as compared with HIV-infected patients without lipodystrophy. Data showing the high prevalence of NASH in HIV-infected individuals are presented. A high rate of progression of NAFLD in a cohort of HIV-infected individuals was observed, regardless of the presence/absence of a combined viral infection (chronic hepatitis C). It has been established that the classic risk factors for NAFLD (high body mass index, dyslipidemia, metabolic syndrome) can contribute to the rapid progression of the disease in people living with HIV, compared with representatives of the general population.

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