High prevalence of metabolic complications in patients with non‐alcoholic fatty liver disease

2004 ◽  
Vol 39 (9) ◽  
pp. 864-869 ◽  
Author(s):  
I. Friis‐Liby ◽  
F. Aldenborg ◽  
P. Jerlstad ◽  
K. Rundström ◽  
E. Björnsson
2021 ◽  
Vol 17 (4) ◽  
pp. 62-67
Author(s):  
M.A. Livzan ◽  
◽  
T.S. Krolevets ◽  
T.V. Kostoglod ◽  
A.V. Kostoglod

The high prevalence of non-alcoholic fatty liver disease and its association with diseases of the metabolic profile causes the interest of doctors of various specialties in the management of patients with this pathology. Due to the accumulation of data on risk factors and disease progression, approaches and attitudes about previously harmless pathology have evolved to understand its potential danger. The formation of the correct approach to the management of patients with non-alcoholic fatty liver disease is a priority task. In this publication, we have analyzed and systematized data from literature concerning the most common problems (mistakes) in the curation of patients with non-alcoholic fatty liver disease.


JGH Open ◽  
2019 ◽  
Vol 3 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Ajay Duseja ◽  
Shaneez Najmy ◽  
Suchet Sachdev ◽  
Arnab Pal ◽  
Rati Ram Sharma ◽  
...  

2019 ◽  
Vol 20 (9) ◽  
pp. 2215 ◽  
Author(s):  
Hamza El Hadi ◽  
Angelo Di Vincenzo ◽  
Roberto Vettor ◽  
Marco Rossato

With the progressive epidemics of obesity, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in adults and children. The increasing prevalence and incidence of NAFLD with advanced fibrosis is concerning because patients appear to experience higher non-liver-related morbidity and mortality than the general population. Recent clinical evidence suggests that NAFLD is directly associated with an increased risk of cardio-metabolic disorders. This mini review describes briefly the current understanding of the pathogenesis of NAFLD, summarizing the link between NAFLD and cardio-metabolic complications, focusing mainly upon ischemic stroke, type 2 diabetes mellitus (DM), hypertension, chronic kidney disease (CKD) and cardiac arrhythmias. In addition, it describes briefly the current understanding of the pathogenesis of NAFLD.


2020 ◽  
Vol 92 (2) ◽  
pp. 48-54 ◽  
Author(s):  
N. A. Cherkashchenko ◽  
M. A. Livzan ◽  
T. S. Krolevets

Aim.To update information about comorbidity of non-alcoholic fatty liver disease (NAFLD) and gallstones disease (GD), evaluation of clinical and laboratory data, including insulin, leptin and adiponectin in individuals with NAFLD in combination with GD. Materials and methods.According to the design, we conducted an open comparative study of 169 patients with NAFLD. The following comparison groups were formed: group 1 (n=95) patients with NAFLD without GD, group 2 (n=35) patients with NAFLD and GD and group 3 (n=39) patients with NAFLD, GD and previous cholecystectomy. Results.A high prevalence of coronary heart disease was found in the group of patients with GD and cholecystectomy (2=6.198,p0.05); positive, statistically significant correlation relationships of cholelithiasis, cholecystectomy with ischemic heart disease (rs=0.172,p0.05 andrs=0.241,p0.05, respectively). There was a statistically significant decrease in total bilirubin and total protein in patients of group 3 (H=7.376,p0.03 and H=6.345,p0.04). The level of leptin is statistically significantly higher and positively interrelated with cholecystectomy (H=5.812,p0.05,rs=0.313,p0.05). Conclusion.Patients with NAFLD, GD and previous cholecystectomy have a high prevalence of coronary heart disease; the phenomenon of insulin and leptin resistance, high level of adiponectin were revealed in patients with NAFLD and gallstones; hyperleptinemia was observed among patients with NAFLD, GD after cholecystectomy.


2019 ◽  
Vol 91 (2) ◽  
pp. 109-117 ◽  
Author(s):  
M V Maevskaya ◽  
V T Ivashkin ◽  
K V Ivashkin ◽  
V D Lunkov ◽  
E O Liusina ◽  
...  

The article presents an update of the role of non-alcoholic fatty liver disease (NAFLD) in cardiometabolic diseases and events: arterial hypertension and components of the metabolic syndrome. A review of NAFLD modern pharmacotherapy has been conducted. Particular attention is paid to the place of ursodeoxycholic acid in the complex treatment of NAFLD.


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