BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system

2004 ◽  
Vol 77 (5) ◽  
pp. 662-669 ◽  
Author(s):  
Ravi J. Tolwani ◽  
Jos� M. Cosgaya ◽  
Sushama Varma ◽  
Reza Jacob ◽  
Lydia E. Kuo ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Myelin Formation

Long-Term Diffusion Impairment of Cerebral White Matter in a Degenerative Disease of the Central and Peripheral Nervous System

2011 ◽  
Vol 27 (2) ◽  
pp. 229-233
Author(s):  
Katrin Sabine Blum ◽  
Christian Hagel ◽  
Eva Neuen-Jacob ◽  
Peter Herkenrath ◽  
Jens Fiehler ◽  
...  
Keyword(s):  
Nervous System ◽  
White Matter ◽  
Peripheral Nervous System ◽  
Degenerative Disease ◽  
Cerebral White Matter

scholarly journals Pathological changes in the central and peripheral nervous system of young long-term diabetics

Diabetologia ◽  
1968 ◽  
Vol 4 (1) ◽  
pp. 34-43 ◽  
Author(s):  
Edith Reske-Nielsen ◽  
Knud Lundb�k
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Pathological Changes

scholarly journals Pathological changes in the central and peripheral nervous system of young long-term diabetics

Diabetologia ◽  
1970 ◽  
Vol 6 (2) ◽  
pp. 98-103 ◽  
Author(s):  
Edith Reske-Nielsen ◽  
Knud Lundbaek ◽  
Gunnar Gregersen ◽  
Aage Harmsen
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Pathological Changes

scholarly journals Long-term Follow-up and Histological Correlation of Peripheral Nervous System Alterations in Neurofibromatosis Type 2

2021 ◽  
Author(s):  
Tim Godel ◽  
Philipp Bäumer ◽  
Said Farschtschi ◽  
Klaus Püschel ◽  
Barbara Hofstadler ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nerve ◽  
Peripheral Nervous System ◽  
Neurofibromatosis Type ◽  
Neurofibromatosis Type 2 ◽  
Nerve Lesions ◽  
Peripheral Nerve Lesions

Abstract Purpose To examine long-term alterations of the dorsal root ganglia (DRG) and the peripheral nerve in patients with neurofibromatosis type 2 (NF2) by in vivo high-resolution magnetic resonance neurography (MRN) and their correlation to histology. Methods In this prospective study the lumbosacral DRG, the right sciatic, tibial, and peroneal nerves were examined in 6 patients diagnosed with NF2 and associated polyneuropathy (PNP) by a standardized MRN protocol at 3 T. Volumes of DRG L3–S2 as well as peripheral nerve lesions were assessed and compared to follow-up examinations after 14–100 months. In one patient, imaging findings were further correlated to histology. Results Follow-up MRN examination showed a non-significant increase of volume for the DRG L3: +0.41% (p = 0.10), L4: +22.41% (p = 0.23), L5: +3.38% (p = 0.09), S1: +10.63% (p = 0.05) and S2: +1.17% (p = 0.57). Likewise, peripheral nerve lesions were not significantly increased regarding size (2.18 mm2 vs. 2.15 mm2, p = 0.89) and number (9.00 vs. 9.33, p = 0.36). Histological analyses identified schwannomas as the major correlate of both DRG hyperplasia and peripheral nerve lesions. For peripheral nerve microlesions additionally clusters of onion-bulb formations were identified. Conclusion Peripheral nervous system alterations seem to be constant or show only a minor increase in adult NF2. Thus, symptoms of PNP may not primarily attributed to the initial schwannoma growth but to secondary long-term processes, with symptoms only occurring if a certain threshold is exceeded. Histology identified grouped areas of Schwann cell proliferations as the correlate of DRG hyperplasia, while for peripheral nerve lesions different patterns could be found.

Long term effects of vincristine on the peripheral nervous system

1993 ◽  
Vol 15 (1) ◽  
pp. 23-27 ◽  
Author(s):  
T. J. Postma ◽  
B. A. Benard ◽  
P. C. Huijgens ◽  
G. J. Ossenkoppele ◽  
J. J. Heimans
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Long Term Effects

Effect of Short-and Long-Term Gonadectomy on Neuroactive Steroid Levels in the Central and Peripheral Nervous System of Male and Female Rats

2010 ◽  
Vol 22 (11) ◽  
pp. 1137-1147 ◽  
Author(s):  
D. Caruso ◽  
M. Pesaresi ◽  
O. Maschi ◽  
S. Giatti ◽  
L. M. Garcia-Segura ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Female Rats ◽  
Neuroactive Steroid ◽  
Male And Female ◽  
Male And Female Rats ◽  
Short And Long Term

Long-Term Effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on the Peripheral Nervous System

1987 ◽  
Vol 7 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Sergio Barbieri ◽  
Carlo Pirovano ◽  
Guglielmo Scarlato ◽  
Paolo Tarchini ◽  
Alessandro Zappa ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Long Term Effects

Retinoic acid regulates myelin formation in the peripheral nervous system

Glia ◽  
2010 ◽  
Vol 58 (12) ◽  
pp. 1451-1464 ◽  
Author(s):  
Maria-Jesus Latasa ◽  
Mario Ituero ◽  
Alejandra Moran-Gonzalez ◽  
Ana Aranda ◽  
Jose Miguel Cosgaya
Keyword(s):  
Nervous System ◽  
Retinoic Acid ◽  
Peripheral Nervous System ◽  
Myelin Formation
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