Molecular mechanism of fatty degeneration in rotator cuff muscle with tendon rupture

2011 ◽  
Vol 29 (6) ◽  
pp. 861-866 ◽  
Author(s):  
Yoshiaki Itoigawa ◽  
Koshi N. Kishimoto ◽  
Hirotaka Sano ◽  
Kazuo Kaneko ◽  
Eiji Itoi
Keyword(s):  
Rotator Cuff ◽  
Molecular Mechanism ◽  
Tendon Rupture ◽  
Fatty Degeneration ◽  
Rotator Cuff Muscle

scholarly journals Quantifying extensibility of rotator cuff muscle with tendon rupture using shear wave elastography: A cadaveric study

2017 ◽  
Vol 61 ◽  
pp. 131-136 ◽  
Author(s):  
Taku Hatta ◽  
Hugo Giambini ◽  
Yoshiaki Itoigawa ◽  
Alexander W. Hooke ◽  
John W. Sperling ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Shear Wave ◽  
Tendon Rupture ◽  
Shear Wave Elastography ◽  
Cadaveric Study ◽  
Rotator Cuff Muscle

scholarly journals The effect of tear size and nerve injury on rotator cuff muscle fatty degeneration in a rodent animal model

2012 ◽  
Vol 21 (7) ◽  
pp. 847-858 ◽  
Author(s):  
H. Mike Kim ◽  
Leesa M. Galatz ◽  
Chanteak Lim ◽  
Necat Havlioglu ◽  
Stavros Thomopoulos
Keyword(s):  
Animal Model ◽  
Rotator Cuff ◽  
Nerve Injury ◽  
Fatty Degeneration ◽  
Rotator Cuff Muscle ◽  
Tear Size ◽  
Rodent Animal Model

scholarly journals Vitamin D level in the rotator cuff muscle and serum correlates with postoperative muscle performance at 1 year after rotator cuff repair

2020 ◽  
Vol 8 (7_suppl6) ◽  
pp. 2325967120S0033
Author(s):  
Sung-Min Rhee ◽  
Hyeon Jang Jeong ◽  
Joo Han Oh
Keyword(s):  
Vitamin D ◽  
Rotator Cuff ◽  
Rotator Cuff Repair ◽  
Functional Outcomes ◽  
Performance Test ◽  
Muscle Power ◽  
Fatty Degeneration ◽  
Muscle Performance ◽  
Rotator Cuff Muscle ◽  
Cuff Repair

Objectives: Previously, we reported that tissue vitamin D (tVD) in the rotator cuff muscle had strong correlation with pre-operative serum vitamin D (sVD). Furthermore, tVD reflected more on the preoperative muscle power. This study was a follow-up study to evaluate correlations of tVD, vitamin D receptor (VDR), and postoperative sVD with rotator cuff muscle performance, fatty degeneration, healing failure, and functional outcomes at 1 year after rotator cuff repair (RCR). Methods: Between March and October in 2017, 36 patients who underwent RCR were prospectively enrolled and 26 patients were followed at 1 year postoperatively and analyzed. tVD was assessed using liquid chromatography, and the VDR was measured by western blotting. sVD was checked preoperatively, 6 months, and 1 year post-operatively. At 1 year after surgery, isokinetic muscle performance test (IMPT), ASES score and Constant score were evaluated, and MRI was used to analyze fatty degeneration and the healing failure. Results: The mean level of sVD at 1 year post-operatively was 20.5 ± 9.2 ng/ml. Only six patients had normal level of sVD (> 20 ng/ml, 23.1%), while 19 patients had insufficiency (10 - 20 ng/ml, 73.0%), and one patient had defi-ciency (< 10 ng/ml, 3.8%). Lower sVD at pre-operatively had lower sVD at 6 months and 1 year post-operatively (all p < 0.05). Higher pre-operative and 1 year post-operative sVD had less deficiency of IMPT in abduction (pre-operative, post-operative; CC; Abduction, -0.324, -0.395, p = 0.047, 0.041, respectively) How-ever, no correlation was found in deficiency of IMPT in ER, IR (pre-operative, post-operative; CC; ER, IR; 0.025, -0.042; p = 0.926, 0.874, respectively; post-operative; CC; ER, IR; -0.250, -0.157; p = 0.333, 0.548, re-spectively). Although, there was no correlation was found between torque of muscle power at 1 year post-operatively with pre- and post-operative sVD (all p > 0.05), higher tVD had higher torque of abduction (CC: 0.440, p = 0.043), and showed tendency of higher torque of external rotation (ER) (CC: 0.335, p = 0.077). There was no correlation of tVD and sVD with functional outcomes, fatty degeneration and re-tear rate (all p > 0.05). VDR showed no correlation with any variables (all p > 0.05). Conclusions: tVD and sVD showed positive correlation with rotator cuff muscle performance at 1 year after RCR. Regarding lower sVD at pre-operatively had lower sVD at 1 year post-operatively, and considering lower sVD had higher deficiency of muscle power, supplementation of vitamin D to these patients with low sVD would enhance rota-tor cuff muscle performance postoperatively.

Reliability of MR Quantification of Rotator Cuff Muscle Fatty Degeneration Using a 2-point Dixon Technique in Comparison with the Goutallier Classification

2017 ◽  
Vol 24 (11) ◽  
pp. 1343-1351 ◽  
Author(s):  
Saya Horiuchi ◽  
Taiki Nozaki ◽  
Atsushi Tasaki ◽  
Akira Yamakawa ◽  
Yasuhito Kaneko ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Fatty Degeneration ◽  
Rotator Cuff Muscle ◽  
Goutallier Classification ◽  
Mr Quantification

Does Extended-Field-of-View Sonography Improve Interrater Reliability for the Detection of Rotator Cuff Muscle Atrophy?

2008 ◽  
Vol 190 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Eoin C. Kavanagh ◽  
George Koulouris ◽  
Laurence Parker ◽  
William B. Morrison ◽  
Diane Bergin ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Muscle Atrophy ◽  
Interrater Reliability ◽  
Field Of View ◽  
Rotator Cuff Muscle ◽  
Extended Field ◽  
Extended Field Of View

Cellular and Molecular Modulation of Rotator Cuff Muscle Pathophysiology

2021 ◽  
Author(s):  
Chengcheng Fu ◽  
Alice H. Huang ◽  
Leesa M. Galatz ◽  
Woojin M. Han
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Muscle ◽  
Molecular Modulation

scholarly journals A Relationship between Calcium Deposit Size with the Pain Intensity on The Patients with Calcified Tendinitis in The Rotator Cuff

2017 ◽  
Vol 6 (01) ◽  
pp. 18
Author(s):  
Indri Wijayanti ◽  
I Nyoman Murdana ◽  
Tirza Z. Tamin
Keyword(s):  
Rotator Cuff ◽  
Pain Intensity ◽  
Muscle Fibers ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Calcium Deposit ◽  
Cross Sectional ◽  
Rotator Cuff Muscle ◽  
Calcium Deposits

Background: Calcified tendeinitis is a disease characterized by calcification of multifocal cells mediated byliving tissue. Calcified tendeinitis may occur due to the collection of calcium in the pouch of supraspinatustendon or may spread between rotator cuff muscle fibers and bursa. This deposit may or may not cause pain ofdiscomfort. The study aim is to determine the correlation of calcium deposit size to the pain intensity in patientswith calcified tendinotis.Methods: A cross-sectional study, on subjects, were diagnosed with calcified tendinitis rotator cuff bymusculoskeletal ultrasonography examination.Results: The twenty subjects, aged 50-70 years old, No significant correlations were found between calciumdeposit size with the pain intensity using VAS, r=0.238, p=0.32.Conclusion. The size of the calcium deposit has not correlated with the pain intensity in rotator cuff calcifiedtendinitis patients. But further research is needed whether the location and form of calcium deposits affect thepain intensity in calcified tendinitis rotator cuff patients.Keywords: calcified tendinitis; calcium deposit size; pain intensity.

scholarly journals Muscular injuries after tendon rupture in the rotator cuff of animal models. Systematic review

2019 ◽  
Vol 08 (02) ◽  
pp. 261
Author(s):  
V.M. Terròn ◽  
E. Muiños-López ◽  
F. Granero-Moltó ◽  
M.A. Esteban ◽  
F. Prosper ◽  
...  
Keyword(s):  
Systematic Review ◽  
Rotator Cuff ◽  
Animal Models ◽  
Tendon Rupture
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