scholarly journals Soluble VEGFR1 reverses BMP2 inhibition of intramembranous ossification during healing of cortical bone defects

2016 ◽  
Vol 35 (7) ◽  
pp. 1461-1469 ◽  
Author(s):  
Kai Hu ◽  
Tatiana Y. Besschetnova ◽  
Bjorn R. Olsen
2006 ◽  
Vol 24 (7) ◽  
pp. 1454-1462 ◽  
Author(s):  
Yanchun Liu ◽  
Shama Ahmad ◽  
Xiao Zheng Shu ◽  
R. Kent Sanders ◽  
Sally Anne Kopesec ◽  
...  

2009 ◽  
Vol 1 (1) ◽  
pp. 77-77
Author(s):  
A De Simone ◽  
G Bruzzese ◽  
G Buono ◽  
C Sicignano ◽  
L Delehaye ◽  
...  

Biomaterials ◽  
1993 ◽  
Vol 14 (1) ◽  
pp. 44-50 ◽  
Author(s):  
K. Anselme ◽  
B. Flautre ◽  
P. Hardouin ◽  
M. Chanavaz ◽  
C. Ustariz ◽  
...  

2015 ◽  
Vol 45 (1) ◽  
pp. 30 ◽  
Author(s):  
Seung-Yun Shin ◽  
Seung-Il Shin ◽  
Seung-Beom Kye ◽  
Seok-Woo Chang ◽  
Jongrak Hong ◽  
...  

2007 ◽  
Vol 28 (4) ◽  
pp. 219-229 ◽  
Author(s):  
Taku KOJIMA ◽  
Paulo H L FREITAS ◽  
Sobhan UBAIDUS ◽  
Akiko SUZUKI ◽  
Minqi LI ◽  
...  

2016 ◽  
Vol 27 (5) ◽  
pp. 502-507 ◽  
Author(s):  
Jucely Aparecida da Rosa ◽  
◽  
Kumiko Koibuchi Sakane ◽  
Karina Cecília Panelli Santos ◽  
Vivian Bradaschia Corrêa ◽  
...  

Abstract This study was conducted to evaluate the effects of treatment with strontium ranelate (SR) on the repair of bone defects and molecular components of bones in femurs. Adult female rats (n=27) were subjected to ovariectomy (OVX) or Sham surgery. Thirty days after surgery, a defect was made in the femur and the animals were then divided into three groups: OVX, SHAM and OVX+SR. Euthanasia was performed four weeks after the bone defect surgery. Repair in bone defect was assessed by computed microtomography (μCT) and chemical composition of cortical bone was analyzed by Fourier transform infrared (FTIR) spectroscopy and energy dispersive X-ray spectroscopy (EDS). The trabecular thickness (Tb.Th) of the newly formed bone in the OVX+SR group was significantly higher than that for the OVX group. The collagen maturity in the OVX+SR group was smaller than in the other two groups. In this group, a significant increase in the amount of strontium (Sr) and a decrease in the amount of calcium (Ca) embedded to bone tissue were also observed. Systemic treatment with SR improved microarchitecture of the newly formed bone inside the defect, but decreased cross-linking of mature collagen in cortical bone.


2013 ◽  
Vol 102 (5) ◽  
pp. 1399-1407 ◽  
Author(s):  
Anindita Chatterjea ◽  
Johan van der Stok ◽  
Charlène B. Danoux ◽  
Huipin Yuan ◽  
Pamela Habibovic ◽  
...  

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