Outcomes after antibiotic megaspacer implantation in patients with severe chronic periprosthetic infections

2020 ◽  
Author(s):  
Sheena J. Amin ◽  
Raj M. Patel ◽  
Christina J. Gutowski ◽  
Tae Won B. Kim
Keyword(s):  
Periprosthetic Infections

scholarly journals Periprosthetic infections: How do we diagnose and treat? Results of an online survey and comparison with international recommendations

2021 ◽  
Author(s):  
Christina Otto‐Lambertz ◽  
Andreas Glauner ◽  
Ayla Yagdiran ◽  
Peer Eysel
Keyword(s):  
Online Survey ◽  
Periprosthetic Infections

scholarly journals Detection of Periprosthetic Infections With Use of Ribosomal RNA-Based Polymerase Chain Reaction

2010 ◽  
Vol 92 (3) ◽  
pp. 654-663 ◽  
Author(s):  
Patrick F Bergin ◽  
Jason D Doppelt ◽  
William G Hamilton ◽  
Gudrun E Mirick ◽  
Angela E Jones ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Ribosomal Rna ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Periprosthetic Infections

Use of Glycosylated Hemoglobin to Identify Diabetics at High Risk for Penile Periprosthetic Infections

1992 ◽  
Vol 36 (5) ◽  
pp. 305
Author(s):  
J. R. BISHOP ◽  
J. W. MOUL ◽  
S. A. SIHELNIK ◽  
D. S. PEPPAS ◽  
T. S. GORMLEY ◽  
...  
Keyword(s):  
High Risk ◽  
Glycosylated Hemoglobin ◽  
Periprosthetic Infections

Periprosthetic Infections of the Shoulder

2019 ◽  
Vol 27 (21) ◽  
pp. e935-e944 ◽  
Author(s):  
E. Scott Paxton ◽  
Andrew Green ◽  
Van S. Krueger
Keyword(s):  
Periprosthetic Infections

scholarly journals Influence of Physicochemical Aspects of Substratum Nanosurface on Bacterial Attachment for Bone Implant Applications

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Kun Mediaswanti
Keyword(s):  
Biofilm Formation ◽  
Bacterial Attachment ◽  
Nanostructured Surface ◽  
Bone Implant ◽  
Implant Materials ◽  
Periprosthetic Infections

Biofilm formation on implant materials is responsible for periprosthetic infections. Bacterial attachment is important as the first stage in biofilm formation. It is meaningful to understand the influence of nanostructured surface on bacterial attachment. This review discusses the influence of physicochemical aspects of substratum nanosurface on bacterial attachment.

Propionibacterium acnes is a causative agent in periprosthetic infections – important implications for the treatment of acne vulgaris

2019 ◽  
Vol 17 (4) ◽  
pp. 454-455
Author(s):  
Christina Otto‐Lambertz ◽  
Norma Jung ◽  
Cord Sunderkötter
Keyword(s):  
Causative Agent ◽  
Propionibacterium Acnes ◽  
Acne Vulgaris ◽  
Periprosthetic Infections

scholarly journals Efficacy of antimicrobial coated orthopaedic implants on the prevention of periprosthetic infections: a systematic review and meta-analysis

2020 ◽  
Vol 5 (4) ◽  
pp. 212-222 ◽  
Author(s):  
Olga D. Savvidou ◽  
Angelos Kaspiris ◽  
Ioannis Trikoupis ◽  
George Kakouratos ◽  
Stavros Goumenos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antimicrobial Agents ◽  
Meta Analysis ◽  
Titanium Implants ◽  
Silver Coating ◽  
Orthopaedic Implant ◽  
Infection Rates ◽  
Implant Surface ◽  
Coated Implant ◽  
Periprosthetic Infections

Abstract. Introduction: Implant-associated infections are a major problem in orthopaedic surgery. Local delivery systems of antimicrobial agents on the implant surface have attracted great interest recently. The purpose of this study was to identify antimicrobial coatings currently used in clinical practice, examining their safety and effectiveness in reducing post-operative infection rates.Materials and Methods: A systematic review was conducted in four databases (Medline, Embase, Cochrane, Cinahl) according to the Preferred Reporting Items for Systematic reviews and Meta-analysis (PRISMA) guidelines up to December 2019, using the key words “orthopaedic implant coated”, “coated implant infection”, “silver coating ” and “antibiotic coating”.Results: Seven articles involving 1307 patients (561 with coated implants and 746 controls who were not) comparing the incidence of periprosthetic infections after the application of internal fracture fixation, total arthroplasties and endoprostheses were evaluated. Three different coating technologies were identified: gentamicin coating for tibia nail and total arthroplasties; silver technology and povidone-iodine coating for tumour endoprostheses and titanium implants. Meta-analysis demonstrated that patients who were treated with antimicrobial coated implants presented lower infection rates compared to controls over the seven studies (Q = 6.1232, I2 = 0.00, 95% CI: 1.717 to 4.986, OR: 2.926, Z= 3.949, p<0.001). Subgroup statistical analysis revealed that each coating technique was effective in the prevention of periprosthetic infections (Q = 9.2606, I2 = 78.40%, 95% CI: 1.401 to 4.070, OR: 2.388, Z= 3.200, p<0.001).Conclusion: All technologies were reported to have good biocompatibility and were effective in the reduction of post-operative peri-prosthetic infection rates.

scholarly journals Treatment of Periprosthetic Infections: An Economic Analysis

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Daniel Hernández-Vaquero ◽  
Mariano Fernández-Fairen ◽  
Ana Torres ◽  
Ann M. Menzie ◽  
José Manuel Fernández-Carreira ◽  
...  
Keyword(s):  
Periprosthetic Infection ◽  
High Risk Patient ◽  
Antibiotic Use ◽  
Current Data ◽  
Behavioral Changes ◽  
Improved Outcomes ◽  
Patient Groups ◽  
Rational Management ◽  
Periprosthetic Infections

This review summarizes the existing economic literature, assesses the value of current data, and presents procedures that are the less costly and more effective options for the treatment of periprosthetic infections of knee and hip. Optimizing antibiotic use in the prevention and treatment of periprosthetic infection, combined with systemic and behavioral changes in the operating room, the detection and treatment of high-risk patient groups, as well as the rational management of the existing infection by using the different procedures according to each particular case, could allow for improved outcomes and lead to the highest quality of life for patients and the lowest economic impact. Nevertheless, the costeffectiveness of different interventions to treat periprosthetic infections remains unclear.

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