Adding surgery as a complementary approach to radioiodine therapy in patients of differentiated thyroid carcinoma with large solitary flat bone metastases: the unresolved issues

2011 ◽  
Vol 105 (6) ◽  
pp. 622-622 ◽  
Author(s):  
Sandip Basu ◽  
Amit Abhyankar

2001 ◽  
Vol 28 (2) ◽  
pp. 203-208 ◽  
Author(s):  
T. Petrich ◽  
A. Widjaja ◽  
T. J. Musholt ◽  
M. Hofmann ◽  
T. Brunkhorst ◽  
...  


2001 ◽  
Vol 86 (4) ◽  
pp. 1568-1573 ◽  
Author(s):  
Marie-Odile Bernier ◽  
Laurence Leenhardt ◽  
Catherine Hoang ◽  
Andre Aurengo ◽  
Jean-Yves Mary ◽  
...  

Data for patients with bone metastases (BMs) of differentiated thyroid carcinoma (DTC) were retrospectively studied to identify factors associated with survival. We especially studied the impact of therapies. Among the 1977 patients followed for DTC in our department from 1958 to 1999, 109 (77 females and 32 males; age range, 20–87 yr) presented BMs. All patients except 1 underwent total thyroidectomy, followed by radioiodine therapy (≥3.7 gigabecquerels) in 95 cases. Survival rates at 5 and 10 yr were 41% and 15%, respectively. Univariate analyses indicated that a young age at BM discovery (P < 0.005) and the discovery of BM as a revealing symptom of DTC (P < 0.05) were features significantly associated with improved survival as well as radioiodine therapy (P < 10−4) and BM complete surgery (P < 0.02). Using multivariate analysis, the detection of BMs as a revealing symptom of thyroid carcinoma (P < 0.0005), the absence of metastasis appearance in other organs than bones during the follow-up (P < 0.03), the cumulative dose of radioiodine therapy (P < 0.0001), and complete BM surgery in young patients (P < 0.04) appeared as independent prognostic features associated with an improved survival.



2000 ◽  
Vol 52 (5) ◽  
pp. 653-659 ◽  
Author(s):  
K. M. Van Tol ◽  
J. M. Hew ◽  
P. L. Jager ◽  
A. Vermey ◽  
R. P. F. Dullaart ◽  
...  


1987 ◽  
Vol 26 (03) ◽  
pp. 139-142 ◽  
Author(s):  
G. Arning ◽  
O. Schober ◽  
H. Hundeshagen ◽  
Ch. Ehrenheim

In the follow-up of differentiated thyroid carcinoma it is discussed whether the tumormarker thyroglobulin can replace the1311 scan, especially when the thyroglobulin serum level is normal. A positive1311 scan of metastases in the follow-up of patients with differentiated thyroid carcinoma combined with a low serum thyroglobulin level is extremely rare. The literature shows a frequency of about 4%. Recently we found 3 cases with a positive1311 scan demonstrating pulmonary and bone metastases whereas the serum thyroglobulin level was low.



2002 ◽  
Vol 57 (1) ◽  
pp. 117-124 ◽  
Author(s):  
Jeroen Schaap ◽  
Carmen F. A. Eustatia-Rutten ◽  
Marcel Stokkel ◽  
Thera P. Links ◽  
Michaela Diamant ◽  
...  


2020 ◽  
Vol 39 (9) ◽  
pp. 1811-1818
Author(s):  
Graziele Aparecida Simões Lima ◽  
Rossana Verónica Mendoza López ◽  
Ricardo Miguel Costa Freitas ◽  
Jose Willegaignon ◽  
Marcelo Tatit Sapienza ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document