Clinicopathologic features of gastric carcinoma with lymphoid stroma in early gastric cancer

2016 ◽  
Vol 114 (6) ◽  
pp. 769-772 ◽  
Author(s):  
Cheal Wung Huh ◽  
Da Hyun Jung ◽  
Hyunki Kim ◽  
Hoguen Kim ◽  
Young Hoon Youn ◽  
...  
2005 ◽  
Vol 16 (8) ◽  
pp. 1232-1236 ◽  
Author(s):  
C. Copie-Bergman ◽  
C. Locher ◽  
M. Levy ◽  
M.T. Chaumette ◽  
C. Haioun ◽  
...  

1997 ◽  
Vol 21 (8) ◽  
pp. 832-836 ◽  
Author(s):  
Kimiya Takeshita ◽  
Masao Tani ◽  
Tooru Honda ◽  
Ichiro Saeki ◽  
Fumio Kando ◽  
...  

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 29-29 ◽  
Author(s):  
T. Bouca-Machado ◽  
H. Santos Sousa ◽  
E. Lima-da-costa ◽  
J. Pinto-de-Sousa ◽  
J. Preto ◽  
...  

29 Background: The aim of this study was to evaluate the characteristics of early gastric cancer (EGC) in comparison to advanced tumors and its role in patient's prognosis. Methods: This study was related to 1,272 patients admitted with gastric or gastroesophageal junction carcinoma in our department, between January 1988 and December 2008. During this period the incidence of EGC was 12.68% (3.62% T0, 42.75% T1a and 53.62% T1b). Several clinical, pathological and staging parameters were evaluated according to classification in EGC and advanced tumors. Results: Significant differences were observed in location (p<0.001); type of resection surgery (p<0.001) and of lymphadenectomy (p=0.008 for Siewert and p<0.001 for Japanese classifications) with less radical surgery in EGC patients. This type of tumors presented characteristics associated with a better prognosis in the following pathological parameters: tumor dimensions (p<0.001), macroscopic form (p<0.001), Ming's classification (p<0.001), venous invasion (p<0.001) and lymphatic permeation (p<0.001). The 5-year survival rate of this series was 33.7%. There were significant differences in survival curves according to classification in EGC and advanced tumors (73% at 5 years and 26% at 5 years, respectively). Cox-regression analysis identified age, T and lymph node ratio as independent prognostic factors. There was no significant differences in age (cut-off 45 years), but there was significant differences in lymph node metastasis (p<0.001). In 23.87% of EGC there was lymph node involvement, with significant differences (p=0.002) according to the depth wall invasion [T0 (100% N0), T1a (91.5% N0, 8.5% N1), T1b (60.8% N0, 21.6% N1, 13.5% N2, 4.1% N3a)]. Conclusions: The EGC percentage in our series was lower in comparison with other countries with high incidence of gastric cancer. The prognosis of the patients with gastric carcinoma continues to be gloomy mainly due to the late diagnosis and, given that the surgical treatment doesn't seem plausible of achieving a margin of significant additional progression, the need for an early diagnosis emerges if an improvement in patient survival is desired. No significant financial relationships to disclose.


2008 ◽  
Vol 8 (4) ◽  
pp. 198 ◽  
Author(s):  
Young Jae Ahn ◽  
Sung Jin Oh ◽  
Jye Won Song ◽  
Wook Ho Kang ◽  
Woo Jin Hyung ◽  
...  

2017 ◽  
Vol 31 (10) ◽  
pp. 4156-4164 ◽  
Author(s):  
Dong Hun Shin ◽  
Gwang Ha Kim ◽  
Bong Eun Lee ◽  
Jong Wook Lee ◽  
Dong Woo Ha ◽  
...  

2016 ◽  
Vol 101 (11-12) ◽  
pp. 562-569
Author(s):  
Si-Hak Lee ◽  
Cheol Woong Choi ◽  
Su Jin Kim ◽  
Dae-Hwan Kim ◽  
Chang In Choi ◽  
...  

This study aimed to clarify the clinicopathologic features and explore treatment strategies for patients with pathologically confirmed advanced gastric cancer (AGC) diagnosed as clinically early gastric cancer (cEGC) before surgery. We included 955 patients who were treated by curative gastrectomy between 2008 and 2013; 42 patients had cEGC. The clinicopathologic features of the patients with cEGC were compared with those of patients with early gastric cancer (EGC); AGC; cancer of the muscularis propria (MP cancer, gastric cancer invading the muscularis propria of the stomach); or SM3 cancer (gastric cancer invading all 3 parts of the submucosal layer). Patients with cEGC had more tumor lymph node metastasis; more lymphatic invasion; and more perineural invasion (all P &lt; 0.001) compared with those with EGC. Patients with cEGC had more tumor lymph node metastasis (P = 0.017) than did patients with SM3. Compared with patients with AGC or MP cancer, patients with cEGC were more likely to be operated on using a laparoscopic procedure and less likely to receive lymph node dissection. Multivariate analysis showed that gross type III [odds ratio (OR), 12.92; P &lt; 0.001] and tumor location (middle body, OR, 2.691; P = 0.009) were significant predictors of cEGC before surgery. Although patients with cEGC had clinicopathologic features similar to those of patients with MP cancer, they were treated like patients with SM3 cancer (e.g., limited use of lymphadenectomy). These findings suggest that patients with cEGC should be given a more aggressive treatment strategy.


2018 ◽  
Vol 11 (5) ◽  
pp. 382-385 ◽  
Author(s):  
Minoru Kato ◽  
Yoshito Hayashi ◽  
Kenji Fukumoto ◽  
Kengo Nagai ◽  
Yoshiki Tsujii ◽  
...  

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