Increased long-term risk of hearing loss in patients with traumatic brain injury: A nationwide population-based study

Background: Long-term mortality may be increased following traumatic brain injury (TBI); however, the degree to which survival could be reduced is unknown. We aimed at modelling life expectancy following post-acute TBI to provide predictions of longevity and quantify differences in survivorship with the general population. Methods: A population-based retrospective cohort study using data from the Rochester Epidemiology Project (REP) was performed. A random sample of patients from Olmsted County, Minnesota with a confirmed TBI between 1987 and 2000 was identified and vital status determined in 2013. Parametric survival modelling was then used to develop a model to predict life expectancy following TBI conditional on age at injury. Survivorship following TBI was also compared with the general population and age- and gender-matched non-head injured REP controls. Results: Seven hundred and sixty nine patients were included in complete case analyses. The median follow-up time was 16.1 years (interquartile range 9.0-20.4) with 120 deaths occurring in the cohort during the study period. Survival after acute TBI was well represented by a Gompertz distribution. Victims of TBI surviving for at least 6 months post-injury demonstrated a much higher ongoing mortality rate compared to the US general population and non-TBI controls (hazard ratio 1.47, 95% CI 1.15-1.87). US general population cohort life table data was used to update the Gompertz model's shape and scale parameters to account for cohort effects and allow prediction of life expectancy in contemporary TBI. Conclusions: Survivors of TBI have decreased life expectancy compared to the general population. This may be secondary to the head injury itself or result from patient characteristics associated with both the propensity for TBI and increased early mortality. Post-TBI life expectancy estimates may be useful to guide prognosis, in public health planning, for actuarial applications and in the extrapolation of outcomes for TBI economic models.

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Young Adults With Traumatic Brain Injury in Long-Term Care Homes: A Population-Based Study

Brain Impairment ◽

10.1375/brim.11.1.31 ◽

2010 ◽

Vol 11 (1) ◽

pp. 31-36 ◽

Cited By ~ 13

Author(s):

Angela Colantonio ◽

Dana Howse ◽

Jigisha Patel

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Long Term Care ◽

Secondary Data ◽

Population Based ◽

Care Homes ◽

Care Needs ◽

Cross Sectional ◽

Term Care

AbstractThe aim of this research was to identify the number and characteristics of adults under the age of 65 with a diagnosis of traumatic brain injury (TBI) living in long-term care homes (nursing homes, homes for the aged and charitable homes) in Ontario, Canada. Methods: The study used a cross-sectional design. Secondary data analysis of a comprehensive provincial database of long-term care homes was conducted. Results: Of the 399 residents coded as having a TBI, 154 were < 65 years of age. Virtually all residents were limited in personal care and required assistance for eating (94.2%), toileting (92.2%) and dressing (99.4%). A large percentage also required care for challenging behaviours, while care needs due to substance abuse was common among 12.3% of TBI residents. Conclusion: As similar research in Australia has found, young persons in long-term care homes in Ontario, Canada, have high level personal health needs, however the appropriateness of this environment is questionable.

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A population-based study on epidemiology of intensive care unit treated traumatic brain injury in Iceland

Acta Anaesthesiologica Scandinavica ◽

10.1111/aas.12869 ◽

2017 ◽

Vol 61 (4) ◽

pp. 408-417 ◽

Cited By ~ 4

Author(s):

G. M. Jonsdottir ◽

S. H. Lund ◽

B. Snorradottir ◽

S. Karason ◽

I. H. Olafsson ◽

...

Keyword(s):

Intensive Care Unit ◽

Traumatic Brain Injury ◽

Intensive Care ◽

Brain Injury ◽

Population Based ◽

Population Based Study

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The Risk of Traumatic Brain Injury Occurring Among Patients with Parkinson Disease: A 14-Year Population-Based Study

World Neurosurgery ◽

10.1016/j.wneu.2018.02.027 ◽

2018 ◽

Vol 113 ◽

pp. e328-e335 ◽

Cited By ~ 4

Author(s):

Tee-Tau Eric Nyam ◽

Chung-Han Ho ◽

Yu-Lin Wang ◽

Sher-Wei Lim ◽

Jhi-Joung Wang ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Parkinson Disease ◽

Population Based ◽

Population Based Study

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Comparison of fall-related traumatic brain injury in residential aged care and community-dwelling older people: A population-based study

Australasian Journal on Ageing ◽

10.1111/ajag.12422 ◽

2017 ◽

Vol 36 (2) ◽

pp. 144-150 ◽

Cited By ~ 4

Author(s):

Lara A Harvey ◽

Rebecca Mitchell ◽

Henry Brodaty ◽

Brian Draper ◽

Jacqueline CT Close

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Older People ◽

Aged Care ◽

Population Based ◽

Community Dwelling ◽

Residential Aged Care ◽

Population Based Study ◽

Community Dwelling Older People

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TP2-3 Long-term survival and five year hospital resource usage following traumatic brain injury in scotland from 1997–2015: a population-based retrospective cohort study

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp-2019-abn.44 ◽

2019 ◽

Vol 90 (3) ◽

pp. e14.2-e14

Author(s):

JJM Loan ◽

NW Scott ◽

JO Jansen

Keyword(s):

Traumatic Brain Injury ◽

Cohort Study ◽

Brain Injury ◽

Population Based ◽

Resource Usage ◽

Hospital Resource ◽

Post Injury ◽

Term Survival ◽

Long Term Survival

AimTo determine if survival and hospital resource usage differ following traumatic brain injury (TBI) compared with head injury without neurological injury(HI).MethodsThis retrospective population-based cohort study included all 25 319 patients admitted to a Scottish NHS hospital from 1997–2015 with TBI. Participants were identified using previously validated ICD-10 based definitions. For comparison, all 194 049 HI cases were identified. Our main outcome measures were hazards of all-cause mortality after TBI, compared with HI, over 18 years follow-up period; and odds of mortality at one month post-injury. Number of days spent as inpatients and number of outpatient attendances per surviving month post-injury were used as measures of resource utilisation.ResultsThe adjusted odds ratio for mortality in the first month post-injury for TBI was 7.12 (95% confidence interval [CI] 6.73–7.52; p<0.001). For the remaining 18 year study period, the hazards of morality after TBI were 0.93 (CI 0.90–0.96; p<0.001). TBI was associated with 2.15 (CI 2.10–2.20; p<0.001) more days spent as inpatient and 1.09 times more outpatient attendances (CI 1.07–1.11; p<0.001) than HI.ConclusionsAlthough initial mortality following TBI is high, survivors of the first month can achieve comparable long-term survival to HI. However this is associated with increased utilisation of hospital services in the TBI group.

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