Improving Survival of T3cN0M0 Glottic Squamous Cell Cancer With Elective Neck Dissection

2021 ◽  
Author(s):  
Zhimou Cai ◽  
Lin Chen ◽  
Jingwei Zhang ◽  
Yihui Wen ◽  
Wenbin Lei
Keyword(s):  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Elective Neck Dissection

scholarly journals Elective Neck Dissection can Improve the Overall Survival and Cancer-Specific Survival of T3cN0M0 Glottic Squamous Cell Cancer

2021 ◽  
Author(s):  
Zhimou Cai ◽  
Lin Chen ◽  
Jiangwei Zhang ◽  
Yihui Wen ◽  
Wen-bin Lei
Keyword(s):  
Overall Survival ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Elective Neck Dissection ◽  
Cancer Specific Survival ◽  
Node Negative ◽  
Considerable Discussion

Abstract How to treat clinically node-negative (cN0) neck in larynx squamous cell cancer (LSCC) has been subject to considerable discussion. The role of elective neck dissection (END) in patients with T3 glottic squamous cell cancer (GSCC) with cN0 is remain unclear. The objective of this study is to elucidate the role of END in improve the outcome of T3cN0M0 GSCC. Patients with T3cN0M0 GSCC in the Surveillance, Epidemiology, and End Results database (SEER) from 2004 to 2015 were extracted and stratified into END and Non-END cohorts, we found that only 22–58% T3cN0M0 GSCC were performed with END. After Propensity score matching (PSM), END cohort had better overall survival (OS) (median survival time: 93 vs 40 months, respectively; p < 0.0001) and cancer-specific survival (CSS) (HR 0.40, 95%CI 0.26 to 0.64, p = 0.0012) than non-END cohort. In addition, Subgroup analysis also indicated END cohort had better OS or CSS than non-END cohort.This study demonstrated that in patients with T3cN0M0 GSCC, END significantly associated with better survival outcomes compared with non-END.

Cervical node metastases in oropharyngeal squamous cell carcinoma: prospective analysis of prevalence and distribution

2002 ◽  
Vol 116 (11) ◽  
pp. 925-928 ◽  
Author(s):  
Jemy Jose ◽  
Andrew P. Coatesworth ◽  
Colin Johnston ◽  
Ken MacLennan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Oropharyngeal Carcinoma ◽  
Neck Node ◽  
Cancer Metastases ◽  
Node Metastases

The treatment of cervical lymph node metastases is an important part of the management of oropharyngeal squamous cell cancer. Metastases are already clinically present in 61 per cent (+ or −2.6 per cent) of patients at presentation. Previous studies concerning the prevalence and distribution of neck node metastases in oropharyngeal carcinoma have been retrospective, and little or no information is available about the histopathological methods used.This study has prospectively analysed 85 neck dissection specimens in 72 consecutive patients with squamous cell carcinoma of the oropharynx, both with clinically N0 and N+ve necks, to identify the prevalence and distribution of cervical metastases. We have used a technique to separate the neck dissection into nodal levels per-operatively, and then embedded the entire specimen for histological examination to avoid missing metastatic disease in small lymph nodes (<3mm diameter).

Neck Dissection in Relation With Disease-Free, Disease-Specific, and Overall Survival of Patients With Squamous Cell Cancer of the Oral Cavity

2014 ◽  
Vol 25 (6) ◽  
pp. 1992-1997 ◽  
Author(s):  
Georgios Koloutsos ◽  
Konstantinos Vahtsevanos ◽  
Athanassios Kyrgidis ◽  
Nikolaos Kechagias ◽  
Stefanos Triaridis ◽  
...  
Keyword(s):  
Overall Survival ◽  
Oral Cavity ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Disease Free ◽  
Disease Specific

Long term results of primary radiotherapy with/without neck dissection for squamous cell cancer of the base of tongue

Head & Neck ◽  
1998 ◽  
Vol 20 (8) ◽  
pp. 668-673 ◽  
Author(s):  
Louis B. Harrison ◽  
Henry J. Lee ◽  
David G. Pfister ◽  
Dennis H. Kraus ◽  
Carol White ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Long Term Results ◽  
Base Of Tongue ◽  
Primary Radiotherapy

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) as a consequence of neck dissection

1997 ◽  
Vol 111 (5) ◽  
pp. 449-453 ◽  
Author(s):  
Thomas W. Mesko ◽  
Orlando Garcia ◽  
Lisa D. Yee ◽  
MaryJo Villar ◽  
Helen Chan
Keyword(s):  
Radiation Therapy ◽  
Neck Dissection ◽  
Antidiuretic Hormone ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Jugular Vein ◽  
Cell Cancer ◽  
Control Group ◽  
Inappropriate Secretion ◽  
High Incidence

AbstractThe syndrome of inappropriate secretion of antidiuretic hormone (SIADH) canhave multiple causes. Surgical neck dissections may have an association with this syndrome and represent the basis for this study. A retrospective review of 50 patients undergoing neck dissections was performed to evaluate for the development of hyponatraemia as a consequence of SIADH. Based on the results of this review, a prospective study of 20 consecutive patients undergoing 22 neck dissections was performed to determine the incidence ofSIADH. A control group of 25 consecutive patients undergoing major non-neck dissection surgery was also studied. SIADH developed in nine of 50 patients (18 per cent) of our retrospective group with a high incidence of development in those who had jugular vein ligation (JVL) (22 per cent), pre-operative radiation therapy (25 per cent) or squamous cell cancers (32 per cent). SIADH developed in six patients undergoing 22 neck dissections (27 per cent) in our prospective group. A high incidence was also noted for those with JVL (42 per cent), pre-operative radiation therapy (67 per cent) or squamous cell cancer (40 per cent). No patients developed symptomatic hyponatraemia. No patients in the prospective control group developed SIADH. Neck dissection surgery is associated with a significant risk for the development of SIADH. Factors such as jugular vein ligation (JVL), pre-operative radiotherapy and squamous cell cancer appear to increase this risk.

Planned neck dissection after chemoradiotherapy in advanced oropharyngeal squamous cell cancer: The role of US, MRI and FDG-PET/TC scans to assess residual neck disease

2014 ◽  
Vol 42 (8) ◽  
pp. 1834-1839 ◽  
Author(s):  
Raul Pellini ◽  
Valentina Manciocco ◽  
Mario Turri-Zanoni ◽  
Antonello Vidiri ◽  
Giuseppe Sanguineti ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Squamous Cell ◽  
Fdg Pet ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Neck Disease
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