Projected numbers of people with movement disorders in the years 2030 and 2050: Implications for sub-Saharan Africa, using essential tremor and Parkinson's disease in Tanzania as an example

2012 ◽  
Vol 27 (9) ◽  
pp. 1204-1205 ◽  
Author(s):  
Catherine Dotchin ◽  
Ahmed Jusabani ◽  
William K. Gray ◽  
Richard Walker
2021 ◽  
pp. e35
Author(s):  
Akintomiwa I. Makanjuola ◽  
Funmilola T. Taiwo ◽  
Joseph O. Yaria ◽  
Rufus O. Akinyemi ◽  
Adesola Ogunniyi

Parkinson’s disease (PD) remains a common neurodegenerative movement disorder with significant morbidity, which is expected to increase worldwide in the coming decades. Since its initial description, much has been elucidated about its etiology, pathogenesis, and the role of genetic and environmental risk factors. Effective treatments, including surgical therapies, have been discovered. Despite these strides, many questions remain unanswered; PD remains an active research area with ongoing efforts to discover newer treatment modalities and identify neuroprotective strategies. As with many neurological conditions, there is an unequal distribution of health resources, resulting in some management challenges in low resource settings, especially sub-Saharan Africa (SSA). In this communication, we provide an overview of PD etiopathogenesis, including genetics and management strategies, including some recent advances with respect to treatment options and disease modification approaches. Finally, we discuss some challenges of PD management in low-resource settings and highlight efforts to turn the tide.


Author(s):  
Robertus M. A. de Bie ◽  
Susanne E. M. Ten Holter

Dystonic tremors are a commonly misdiagnosed group of primary tremor disorders, typically mistaken for Parkinson’s disease or essential tremor. Like most movement disorders, this is a clinical diagnosis, so the overlap in some features between all of these disorders can be confusing to less experienced and even more experienced physicians. A tremor in the presence of a dystonia is a dystonic tremor syndrome, regardless of the clinical features. Treatment of dystonic tremor can be challenging without the same gratifying response seen to levodopa in tremor associated with Parkinson’s disease or to beta-blockers and primidone in essential tremor. Deep-brain stimulation remains an option in the most disabling cases.


Brain ◽  
2014 ◽  
Vol 137 (10) ◽  
pp. 2731-2742 ◽  
Author(s):  
R. Cilia ◽  
A. Akpalu ◽  
F. S. Sarfo ◽  
M. Cham ◽  
M. Amboni ◽  
...  

Author(s):  
Sreekanth Rudraraju ◽  
The Nguyen

Parkinson’s disease (PD) and essential tremor (ET) are two common but unrelated diseases that cause movement disorders often involving with severe tremor. The two diseases affects tens of millions of people worldwide, but there is no known cure for them. The tremor not only pose difficulty in completing daily tasks but also impair patients’ social confidence. The objective of this project is to develop a wearable tremor reduction device for the upper limb. The device is obviously different from any previous devices because it is compact, lightweight, comfortable to wear and effective. It is expected to help patients manage the tremor symptoms and regain their normal life.


2012 ◽  
Vol 500 ◽  
pp. 596-602 ◽  
Author(s):  
Jun Zhou ◽  
Pei Chao Liu ◽  
Saif Ullah ◽  
Yun Feng Zhang ◽  
Shou Lei Li ◽  
...  

Currently, deep brain stimulation (DBS) is one of the most effective surgical treatments of treating serious stubborn resistance movement disorders (such as Parkinson's disease, essential tremor and dystonia, etc.). The nerve probe has been greatly favored by the authorities and scientists with the respect to the role it acted as the main brain stimulation tool. This article mainly introduces the materials of brain stimulated micro-electrode, the matched specifications and the evaluation on the compound functions in the developing course. The application prosperity and its development trendy will also be included with the intention to help people gain more systematic acknowledgement on the electrodes for deep brain stimulation.


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