Wearable Tremor Reduction Device (TRD) for Human Hands and Arms

2018 ◽  
Author(s):  
Sreekanth Rudraraju ◽  
The Nguyen
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Upper Limb ◽  
Movement Disorders ◽  
Normal Life ◽  
Human Hands

Parkinson’s disease (PD) and essential tremor (ET) are two common but unrelated diseases that cause movement disorders often involving with severe tremor. The two diseases affects tens of millions of people worldwide, but there is no known cure for them. The tremor not only pose difficulty in completing daily tasks but also impair patients’ social confidence. The objective of this project is to develop a wearable tremor reduction device for the upper limb. The device is obviously different from any previous devices because it is compact, lightweight, comfortable to wear and effective. It is expected to help patients manage the tremor symptoms and regain their normal life.

Objective Quantitative Assessment of Movement Disorders Through Analysis of Static Handwritten Characters

2015 ◽  
Author(s):  
Naiqian Zhi ◽  
Beverly K. Jaeger ◽  
Andrew Gouldstone ◽  
Samuel Frank ◽  
Rifat Sipahi
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Upper Limb ◽  
Movement Disorders ◽  
Healthy Subjects ◽  
Quantitative Assessment ◽  
Clinical Tests ◽  
Assessment Approach

Movement disorders associated with Essential Tremor (ET) and Parkinson’s disease (PD) can negatively impact use of the upper limb for many precision tasks, including handwriting. Both ET and PD can be assessed through clinical tests which are, however, relatively subjective. This assessment approach possesses inherent logistical and resolution limitations. To address this, here we present objective computerized metrics intended to assess and quantify the extent to which static writing samples display the effects of ET and PD. Specifically, these metrics are tested in their ability to measure tremor by comparing unaffected writing samples with those affected by artificially induced tremor on healthy subjects, and also by comparing healthy writing samples with symptomatic writing samples collected from PD patients reporting micrographia. Our findings indicate that the presented metrics can be utilized for assessment, leading to a toolset capable of objectively monitoring static handwriting changes associated with symptom variations in ET and/or PD patients.

A Tremor with an Abnormal Posture

2016 ◽  
Author(s):  
Robertus M. A. de Bie ◽  
Susanne E. M. Ten Holter
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Essential Tremor ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Beta Blockers ◽  
Dystonic Tremor ◽  
Abnormal Posture ◽  
Deep Brain

Dystonic tremors are a commonly misdiagnosed group of primary tremor disorders, typically mistaken for Parkinson’s disease or essential tremor. Like most movement disorders, this is a clinical diagnosis, so the overlap in some features between all of these disorders can be confusing to less experienced and even more experienced physicians. A tremor in the presence of a dystonia is a dystonic tremor syndrome, regardless of the clinical features. Treatment of dystonic tremor can be challenging without the same gratifying response seen to levodopa in tremor associated with Parkinson’s disease or to beta-blockers and primidone in essential tremor. Deep-brain stimulation remains an option in the most disabling cases.

Review of Deep Brain Stimulation Micro-Electrodes

2012 ◽  
Vol 500 ◽  
pp. 596-602 ◽  
Author(s):  
Jun Zhou ◽  
Pei Chao Liu ◽  
Saif Ullah ◽  
Yun Feng Zhang ◽  
Shou Lei Li ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Essential Tremor ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Surgical Treatments ◽  
Resistance Movement ◽  
Deep Brain

Currently, deep brain stimulation (DBS) is one of the most effective surgical treatments of treating serious stubborn resistance movement disorders (such as Parkinson's disease, essential tremor and dystonia, etc.). The nerve probe has been greatly favored by the authorities and scientists with the respect to the role it acted as the main brain stimulation tool. This article mainly introduces the materials of brain stimulated micro-electrode, the matched specifications and the evaluation on the compound functions in the developing course. The application prosperity and its development trendy will also be included with the intention to help people gain more systematic acknowledgement on the electrodes for deep brain stimulation.

Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders

1996 ◽  
Vol 84 (2) ◽  
pp. 203-214 ◽  
Author(s):  
Alim Louis Benabid ◽  
Pierre Pollak ◽  
Dongming Gao ◽  
Dominique Hoffmann ◽  
Patricia Limousin ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Movement Disorders ◽  
Content Type ◽  
Suppression Effect ◽  
Test Stimulation ◽  
Bilateral Surgery ◽  
Stimulation Of

✓ Tremor was suppressed by test stimulation of the thalamic ventralis intermedius (VIM) nucleus at high frequency (130 Hz) during stereotaxy in nonanesthetized patients suffering from Parkinson's disease or essential tremor. Ventralis intermedius stimulation has since been used by the authors over the last 8 years as a treatment in 117 patients with movement disorders (80 cases of Parkinson's disease, 20 cases of essential tremor, and 17 cases of various dyskinesias and dystonias including four multiple sclerosis). Chronic electrodes were stereotactically implanted in the VIM and connected to a programmable stimulator. Results depend on the indication. In Parkinson's disease patients, tremor, but not bradykinesia and rigidity, was selectively suppressed for as long as 8 years. Administration ofl-Dopa was decreased by more than 30% in 40 Parkinson's disease patients. In essential tremor patients, results were satisfactory but deteriorated with time in 18.5% of cases, mainly for patients who presented an action component of their tremor. In other types of dyskinesias (except multiple sclerosis), results were much less favorable. Fifty-nine patients underwent bilateral implantation and 14 other patients received implantation contralateral to a previous thalamotomy. Thirty-seven patients (31.6%) experienced minor side effects, which were always well tolerated and immediately reversible. Three secondary scalp infections led to temporary removal of the implanted material. There was no permanent morbidity. This tremor suppression effect could be due to the inhibition or jamming of a retroactive loop. Chronic VIM stimulation, which is reversible, adaptable, and well tolerated even by patients undergoing bilateral surgery (74 of 117 patients) and by elderly patients, should replace thalamotomy in the regular surgical treatment of parkinsonian and essential tremors.

Depression symptoms in movement disorders: Comparing Parkinson's disease, dystonia, and essential tremor

2007 ◽  
Vol 22 (5) ◽  
pp. 666-672 ◽  
Author(s):  
Kimberly M. Miller ◽  
Michael S. Okun ◽  
Hubert F. Fernandez ◽  
Charles E. Jacobson ◽  
Ramon L. Rodriguez ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Movement Disorders ◽  
Depression Symptoms

scholarly journals Transitioning from Unilateral to Bilateral Upper Limb Tremor Therapy for Parkinson’s Disease and Essential Tremor Using Botulinum Toxin: Case Series

Toxins ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 394 ◽  
Author(s):  
Olivia Samotus ◽  
Jack Lee ◽  
Mandar Jog
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Botulinum Toxin ◽  
Essential Tremor ◽  
Upper Limb ◽  
Kinematic Analysis ◽  
Rating Scale ◽  
Pilot Trial ◽  
Case Series ◽  
Preliminary Finding

Botulinum toxin type A (BoNT-A) injections guided by kinematic analysis for unilateral upper limb essential tremor (ET) and Parkinson’s disease (PD) tremor therapy has demonstrated efficacy, improvements in quality of life (QoL) and arm functionality. In this open-label pilot trial, 5 ET and 2 PD participants decided to switch from receiving long-term unilateral arm treatment to now bilateral BoNT-A arm therapy in their other tremulous arm which worsened over time. Injection patterns were based on kinematic analysis. Efficacy endpoints including kinematic analysis, Fahn-Tolosa-Marin tremor rating scale, QoL questionnaire, and maximal grip strength were collected over 2 treatments and 2 follow-up visits totaling 18-weeks. BoNT-A decreased wrist tremor amplitude by 84.6% and 89.6% 6-weeks following the 1st injection in the newly-treated limb in ET and PD participants, respectively. PD participants started with worse QoL but demonstrated an additional improvement in QoL by 29.9% for switching to bilateral treatment, whereas ET participants did not. Left and right arm tremor also did not share commonalities in severity or dose. This preliminary finding suggests trends for transitioning to bilateral therapy and warrants further studies to evaluate efficacy of bilateral tremor BoNT-A therapy in a larger cohort of PD and ET patients.

Movement Disorders 1: Tourette’s Syndrome, Essential Tremor, and Parkinson’s Disease (DRAFT)

2018 ◽  
Author(s):  
Tamara Kaplan ◽  
Tracey Milligan
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Movement Disorders ◽  
Postural Instability ◽  
Tourette's Syndrome ◽  
Tourette’S Syndrome ◽  
Resting Tremor ◽  
Kinetic Tremor ◽  
Vocal Tics

The video in this chapter explores movement disorders, and focuses on Tourette’s Syndrome, Essential tremor, and Parkinson’s Disease. It outlines the characteristics of each, such as motor and vocal tics in Tourette’s Syndrome, postural or kinetic tremor in Essential tremor, and the four hallmark features of Parkinson’s Disease (bradykinesia, resting tremor, cogwheel rigidity, and postural instability).

Sign in / Sign up

Export Citation Format

Share Document