Parallel-transmission-enabled three-dimensional T2-weighted imaging of the human brain at 7 Tesla

2014 ◽  
Vol 73 (6) ◽  
pp. 2195-2203 ◽  
Author(s):  
Aurélien Massire ◽  
Alexandre Vignaud ◽  
Benjamin Robert ◽  
Denis Le Bihan ◽  
Nicolas Boulant ◽  
...  
Keyword(s):  
Human Brain ◽  
Three Dimensional ◽  
7 Tesla ◽  
Parallel Transmission

scholarly journals Distributing coil elements in three dimensions enhances parallel transmission multiband RF performance: A simulation study in the human brain at 7 Tesla

2016 ◽  
Vol 75 (6) ◽  
pp. 2464-2472 ◽  
Author(s):  
Xiaoping Wu ◽  
Jinfeng Tian ◽  
Sebastian Schmitter ◽  
J. Tommy Vaughan ◽  
Kâmil Uğurbil ◽  
...  
Keyword(s):  
Human Brain ◽  
Simulation Study ◽  
Three Dimensions ◽  
7 Tesla ◽  
Parallel Transmission ◽  
Rf Performance

scholarly journals 7 Tesla MRI of the ex vivo human brain at 100 micron resolution

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Brian L. Edlow ◽  
Azma Mareyam ◽  
Andreas Horn ◽  
Jonathan R. Polimeni ◽  
Thomas Witzel ◽  
...  
Keyword(s):  
Human Brain ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Academic Community ◽  
7 Tesla ◽  
Brain Anatomy ◽  
Isotropic Resolution ◽  
Scan Time ◽  
Brain Specimen ◽  
7 Tesla Mri

Abstract We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The brain specimen was donated by a 58-year-old woman who had no history of neurological disease and died of non-neurological causes. After fixation in 10% formalin, the specimen was imaged on a 7 Tesla MRI scanner at 100 µm isotropic resolution using a custom-built 31-channel receive array coil. Single-echo multi-flip Fast Low-Angle SHot (FLASH) data were acquired over 100 hours of scan time (25 hours per flip angle), allowing derivation of synthesized FLASH volumes. This dataset provides an unprecedented view of the three-dimensional neuroanatomy of the human brain. To optimize the utility of this resource, we warped the dataset into standard stereotactic space. We now distribute the dataset in both native space and stereotactic space to the academic community via multiple platforms. We envision that this dataset will have a broad range of investigational, educational, and clinical applications that will advance understanding of human brain anatomy in health and disease.

scholarly journals 7 Tesla MRI of the ex vivo human brain at 100 micron resolution

2019 ◽  
Author(s):  
Brian L. Edlow ◽  
Azma Mareyam ◽  
Andreas Horn ◽  
Jonathan R. Polimeni ◽  
Thomas Witzel ◽  
...  
Keyword(s):  
Human Brain ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Academic Community ◽  
7 Tesla ◽  
Brain Anatomy ◽  
Isotropic Resolution ◽  
Scan Time ◽  
Brain Specimen ◽  
7 Tesla Mri

AbstractWe present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The brain specimen was donated by a 58-year-old woman who had no history of neurological disease and died of non-neurological causes. After fixation in 10% formalin, the specimen was imaged on a 7 Tesla MRI scanner at 100 μm isotropic resolution using a custom-built 31-channel receive array coil. Single-echo multi-flip Fast Low-Angle SHot (FLASH) data were acquired over 100 hours of scan time (25 hours per flip angle), allowing derivation of a T1 parameter map and synthesized FLASH volumes. This dataset provides an unprecedented view of the three-dimensional neuroanatomy of the human brain. To optimize the utility of this resource, we warped the dataset into standard stereotactic space. We now distribute the dataset in both native space and stereotactic space to the academic community via multiple platforms. We envision that this dataset will have a broad range of investigational, educational, and clinical applications that will advance understanding of human brain anatomy in health and disease.

Construction and verification of a three-dimensional digital human brain atlas

2011 ◽  
Vol 31 (3) ◽  
pp. 291-294
Author(s):  
Zhi-rong YANG ◽  
Yong-jie LI ◽  
Teng MA
Keyword(s):  
Human Brain ◽  
Three Dimensional ◽  
Brain Atlas ◽  
Digital Human

scholarly journals Fast diffusion kurtosis mapping of human brain at 7 Tesla with hybrid principal component analyses

IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Fangrong Zong ◽  
Jiaxin Du ◽  
Xiaofeng Deng ◽  
Xubin Chai ◽  
Yan Zhuo ◽  
...  
Keyword(s):  
Human Brain ◽  
Principal Component ◽  
7 Tesla ◽  
Fast Diffusion ◽  
Principal Component Analyses ◽  
Diffusion Kurtosis

scholarly journals Alteration within the Hippocampal Volume in Patients with LHON Disease—7 Tesla MRI Study

2020 ◽  
Vol 10 (1) ◽  
pp. 14
Author(s):  
Cezary Grochowski ◽  
Kamil Jonak ◽  
Marcin Maciejewski ◽  
Andrzej Stępniewski ◽  
Mansur Rahnama-Hezavah
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Molecular Layer ◽  
Three Dimensional ◽  
Hippocampal Volume ◽  
7 Tesla ◽  
Diagnostic Process ◽  
Resonance Imaging ◽  
The Right

Purpose: The aim of this study was to assess the volumetry of the hippocampus in the Leber’s hereditary optic neuropathy (LHON) of blind patients. Methods: A total of 25 patients with LHON were randomly included into the study from the national health database. A total of 15 patients were selected according to the inclusion criteria. The submillimeter segmentation of the hippocampus was based on three-dimensional spoiled gradient recalled acquisition in steady state (3D-SPGR) BRAVO 7T magnetic resonance imaging (MRI) protocol. Results: Statistical analysis revealed that compared to healthy controls (HC), LHON subjects had multiple significant differences only in the right hippocampus, including a significantly higher volume of hippocampal tail (p = 0.009), subiculum body (p = 0.018), CA1 body (p = 0.002), hippocampal fissure (p = 0.046), molecular layer hippocampus (HP) body (p = 0.014), CA3 body (p = 0.006), Granule Cell (GC) and Molecular Layer (ML) of the Dentate Gyrus (DG)–GC ML DG body (p = 0.003), CA4 body (p = 0.001), whole hippocampal body (p = 0.018), and the whole hippocampus volume (p = 0.023). Discussion: The ultra-high-field magnetic resonance imaging allowed hippocampus quality visualization and analysis, serving as a powerful in vivo diagnostic tool in the diagnostic process and LHON disease course assessment. The study confirmed previous reports regarding volumetry of hippocampus in blind individuals.

scholarly journals Whole-brain three-dimensional T2-weighted BOLD functional magnetic resonance imaging at 7 Tesla

2013 ◽  
Vol 72 (6) ◽  
pp. 1530-1540 ◽  
Author(s):  
Jun Hua ◽  
Qin Qin ◽  
Peter C.M. van Zijl ◽  
James J. Pekar ◽  
Craig K. Jones
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Three Dimensional ◽  
7 Tesla ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Whole Brain

White matter fiber tracts of the human brain: Three-dimensional mapping at microscopic resolution, topography and intersubject variability

NeuroImage ◽  
2006 ◽  
Vol 29 (4) ◽  
pp. 1092-1105 ◽  
Author(s):  
Uli Bürgel ◽  
Katrin Amunts ◽  
Lars Hoemke ◽  
Hartmut Mohlberg ◽  
Joachim M. Gilsbach ◽  
...  
Keyword(s):  
White Matter ◽  
Human Brain ◽  
Three Dimensional ◽  
Intersubject Variability ◽  
Fiber Tracts ◽  
Three Dimensional Mapping ◽  
White Matter Fiber Tracts ◽  
Dimensional Mapping
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