Demonstration of cytokeratins and an epithelial membrane antigen in chondroid chordoma

1987 ◽  
Vol 153 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Jonathan R. Salisbury

1983 ◽  
Vol 55 (6) ◽  
pp. 670-675 ◽  
Author(s):  
R. D. POCOCK ◽  
S. K. IBRAHIM ◽  
J. P. SLOANE ◽  
B. A. J. PONDER ◽  
R. J. SHEARER


2009 ◽  
Vol 37 (4) ◽  
pp. 1252-1257 ◽  
Author(s):  
L Gong ◽  
Y-H Li ◽  
X-L He ◽  
Q Wang ◽  
L Yao ◽  
...  

Primary intrapulmonary thymomas (PIT), which are intrapulmonary tumours without an associated mediastinal component, are very rare; only 29 cases of PIT have been described in the literature since 1951. This report presents a case of PIT in a 59-year old Chinese woman with a type A thymoma (including its pathogenesis, clinical pathological characteristics, immunological phenotype, treatment and prognosis), in the context of a review of the current literature. The origin of thymomas in this unusual location remains unknown. In this case, immunohistochemical analysis demonstrated that the epithelial component was strongly positive for cytokeratin and focally reactive for epithelial membrane antigen. It is concluded that PIT should be considered when the histopathological appearance of a lung tumour is not typical of other pulmonary neoplasms. Complete resection appears sufficient in non-malignant tumours, while in cases of partial resection or malignancy, adjuvant radiotherapy should be considered. Long-term regular clinical follow-up is also warranted, due to the risk of late local recurrence.



1985 ◽  
Vol 99 (5) ◽  
pp. 485-489 ◽  
Author(s):  
M. Hasegawa ◽  
W. Nishijima ◽  
I. Watanabe ◽  
M. Nasu ◽  
R. Kamiyama

AbstractA 36-year-old male with a primary chondroid is presented. This tumour arose from the base of the temporal bone and extended to the mastoid cavity. It involved the facial nerve and was adherent to the internal jugular vein and internal carotid artery. The tumour was excised and the patient has been carefully followed up for 10 years. He has shown no evidence of local recurrence, intracranial extension of the residual tumour and distant metastasis.



2004 ◽  
Vol 128 (8) ◽  
pp. 918-921
Author(s):  
Michelle Reid-Nicholson ◽  
Muhammed Idrees ◽  
Giorgio Perino ◽  
Prodromos Hytiroglou

Abstract Sarcomatoid carcinoma of the small bowel is rare; to our knowledge, 19 cases have been reported to date in the English literature under several names. We report an additional case occurring in the jejunum of a 55-year-old man. The tumor was a polypoid 7.5-cm mass, which infiltrated the full thickness of the intestinal wall and the serosa of an adhesed loop of small bowel. On microscopic examination, the neoplasm was composed of sheets of spindle cells; focally, an anaplastic component was present, including tumor giant cells with bizarre nuclei. On immunohistochemical stains, tumor cells were positive for cytokeratin 7, cytokeratin AE1/AE3, vimentin, and focally, epithelial membrane antigen. No staining for cytokeratin 20 was found. Sarcomatoid carcinoma must be kept in mind in the differential diagnosis of malignant spindle cell tumors of the small bowel. As consensus regarding the terminology of these rare tumors is being reached, immunohistochemical stains are essential for accurate diagnosis.



2000 ◽  
Vol 43 (4) ◽  
pp. 401
Author(s):  
Hye Jeon Jung ◽  
Hyun Sook Kim ◽  
Joo Seung Kim ◽  
Eun Kyung Kim ◽  
Hee In Kang ◽  
...  


1982 ◽  
Vol 57 (6) ◽  
pp. 842-845 ◽  
Author(s):  
W. Craig Clark ◽  
Jon H. Robertson ◽  
Rafael Lara

✓ A case of the very rare chondroid variant of chordomas at the base of the skull is presented. The characteristic presentation, radiological and computerized tomographic appearance, findings at surgery, pathology, and treatment of this lesion are discussed. Neurosurgeons should be aware of this variant, due to its predilection for occurrence at the base of the skull and its more favorable prognosis compared with that of typical chordoma.



1985 ◽  
Vol 1 (2) ◽  
pp. 161-163 ◽  
Author(s):  
Gia-Khanh Nguyen ◽  
Edward S. Johnson ◽  
Bruce W. Mielke


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