Critical evaluation of elective termination of pregnancy in a tertiary fetal medicine center during 43 months: correlation of prenatal diagnosis findings and postmortem examination

2006 ◽  
Vol 26 (11) ◽  
pp. 1084-1088 ◽  
Author(s):  
Carla Ramalho ◽  
Alexandra Matias ◽  
Otília Brandão ◽  
Nuno Montenegro

2011 ◽  
Vol 44 (03) ◽  
pp. 489-493
Author(s):  
Poornima Kadagad ◽  
Pascal Pinto ◽  
Rajesh Powar

ABSTRACT Objectives: To assess the attitudes of pregnant women and mothers of children with orofacial clefts toward prenatal diagnosis of clefts and elective termination of pregnancy, and to investigate their opinion about who makes reproductive decisions in the family. Design: Two hundred subjects were included in the study prospectively regarding hypothetical prenatal ultrasound diagnosis of clefts. Setting: The study was done in a private tertiary care institution and a teaching hospital. Subjects/Participants: One hundred pregnant women consulting the Obstetrics department and 100 mothers of children with orofacial clefts in the Cleft and Craniofacial Unit were selected. Materials and Methods: Group I subjects were interviewed using a questionnaire and were shown preoperative and postoperative pictures of children treated for cleft lip and palate. Group II subjects were interviewed using a questionnaire. Results: Only 3% of Group I subjects and 2% of Group II opined that they would choose the elective termination of pregnancy if the fetus was diagnosed with a cleft on an ultrasound scan. In Group II, 70% subjects wished to have known about pregnancy affected with cleft prenatally and 96% said they would definitely avail ultrasound scans to determine pregnancy affected by clefts in future. Conclusions: Majority of the respondents from both the groups chose to continue with the pregnancy affected with a cleft when questioned regarding hypothetical prenatal ultrasound diagnosis of the cleft.



2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Fabiana Ramos ◽  
Sofia Maia ◽  
Miguel Branco ◽  
Joana Raposo ◽  
Joaquim Sá ◽  
...  

Objective. To evaluate the quality of prenatal results in all cases of termination of pregnancy (TOP) due to fetal abnormalities in a tertiary prenatal diagnosis center. Material and Methods. Retrospective analysis of the 385 TOP performed on our department due to fetal abnormalities between January 1, 2000, and December 31, 2007. We compared all data for agreement between the ultrasound, genetic, and postmortem findings, regarding the abnormalities identified in the etiological diagnosis and its prognosis. Results. Chromosome abnormalities were the most common indication for TOP (39%), followed by abnormalities of CNS (20%), monogenic disorders (11%), sequences (9.6%), polimalformative syndromes (5.2%), and isolated congenital heart diseases (4%). Total agreement was 21%. Further abnormalities were identified in 79%. The data collected after TOP changed the etiologic diagnosis in 21% but the prognosis was changed in only one fetus. Discussion. This study corroborates the necessity of a multidisciplinary team in prenatal diagnosis centers. Their work remarkably improves the genetic counseling and represents an important aspect in quality control of the information given to a couple previously to a TOP.



2012 ◽  
Vol 32 (11) ◽  
pp. 1109-1113 ◽  
Author(s):  
Ayman Alsulaiman ◽  
Jenny Hewison ◽  
Khaled K. Abu-Amero ◽  
Shenaz Ahmed ◽  
Josephine M. Green ◽  
...  


2018 ◽  
Vol 97 (10) ◽  
pp. 1228-1236 ◽  
Author(s):  
Stina Lou ◽  
Kathrine Carstensen ◽  
Olav Bjørn Petersen ◽  
Camilla Palmhøj Nielsen ◽  
Lone Hvidman ◽  
...  


2018 ◽  
Vol 46 (6) ◽  
pp. 631-639
Author(s):  
Raul Moreira Neto ◽  
Selma Porovic

AbstractFetal neurology is evolving as an area of great interest in prenatal diagnosis and fetal medicine. The identification and diagnosis of brain damage prenatally has been a great challenge in obstetrics for many years. Investigations of fetal behavior in comparison with morphological studies led to the conclusion that fetal behavioral patterns directly reflect developmental and maturational processes of the fetal central nervous system (CNS). Four-dimensional (4D) ultrasound has greatly improved the assessment of the quality of the fetal spontaneous movements, and enabled a better evaluation of fetal behavior. The assessment of normal neurobehavioral development by 4D ultrasound provided the opportunity to investigate functional characteristics of the fetus that could predict neurological developmental dysfunction. Some studies have already been carried out to evaluate this new methodology in the observation of fetal behavior during different stages of gestation, in an attempt to better understand the relationships between the maturation of the CNS of the fetus and its implications on its behavior pattern. We present a review of literature on fetal behavior by 4D ultrasound.



JAMA ◽  
1976 ◽  
Vol 236 (26) ◽  
pp. 2942a-2943
Author(s):  
J. P. Annis


2004 ◽  
Vol 104 (5, Part 1) ◽  
pp. 957-964 ◽  
Author(s):  
Allyson J. Peller ◽  
Marie-Noel Westgate ◽  
Lewis B. Holmes


2000 ◽  
Vol 15 (3) ◽  
pp. 146-151 ◽  
Author(s):  
Mathias B. Forrester ◽  
Ruth D. Merz


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