Using full-factorial design analysis and response surface methodology to better understand the production of cationized chitosan from epoxides

Supercritical CO2extraction ofPlumula nelumbinisoil rich in γ-sitosterol was investigated with a 42full factorial design and response surface analysis. At optimal conditions (P=35 MPa,T=55 C,dp=0.22 mm,Q=2.0 L/min), the yield of the extracted oil was up to 12.2%, in which the concentration of γ-sitosterol was 7.38%, indicating that the γ-sitosterol contents inPlumula nelumbinisand its oil were much higher than that in other vegetables.

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Optimization of pyrocatechol violet biosorption by Robinia pseudoacacia leaf powder using response surface methodology: kinetic, isotherm and thermodynamic studies

Journal of Water Reuse and Desalination ◽

10.2166/wrd.2015.054 ◽

2015 ◽

Vol 6 (2) ◽

pp. 333-344 ◽

Cited By ~ 1

Author(s):

Neda Khorshidi ◽

Ali Niazi

Keyword(s):

Response Surface Methodology ◽

Factorial Design ◽

Response Surface ◽

Robinia Pseudoacacia ◽

Freundlich Isotherm ◽

Second Order ◽

Full Factorial Design ◽

Order Kinetic ◽

Pyrocatechol Violet ◽

Full Factorial

We have investigated the biosorption of pyrocatechol violet (PCV) from aqueous solutions by Robinia pseudoacacia tree leaves as a low-cost and eco-friendly biosorbent. A full factorial design was performed for screening the main variables and their interactions, which reduces the large total number of experiments. Results of the full factorial design (24) based on an analysis of variance (ANOVA) demonstrated that the initial PCV concentration, contact time, pH and temperature are statistically significant. Box-Behnken design, a response surface methodology, was used for further optimization of these selected factors. The ANOVA and some statistical tests such as lack-of-fit and coefficient of determination (R2) showed good fit of the experimental data to the second-order polynomial model. The Langmuir and Freundlich isotherm models were used to describe the equilibrium isotherms. Equilibrium data fitted well with the Freundlich isotherm model (R2 > 0.97). In addition, thermodynamic parameters (ΔG°, ΔH° and ΔS°) were calculated, these parameters show that the biosorption process was spontaneous (ΔG° = −2.423) and exothermic (ΔH° = −9.67). The biosorption kinetic data were fitted with the pseudo-second-order kinetic model (R2 > 0.999). These results confirm that R. pseudoacacia leaves have good potential for removal of PCV from aqueous solution.

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Optimisation of ultrasound-assisted extraction conditions for maximal recovery of active monacolins and removal of toxic citrinin from red yeast rice by a full factorial design coupled with response surface methodology

Food Chemistry ◽

10.1016/j.foodchem.2014.08.080 ◽

2015 ◽

Vol 170 ◽

pp. 186-192 ◽

Cited By ~ 38

Author(s):

Guisheng Zhou ◽

Lei Fu ◽

Xiaobo Li

Keyword(s):

Response Surface Methodology ◽

Factorial Design ◽

Response Surface ◽

Full Factorial Design ◽

Red Yeast Rice ◽

Ultrasound Assisted Extraction ◽

Red Yeast ◽

Assisted Extraction ◽

Ultrasound Assisted ◽

Full Factorial

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Impact of Indoor Physical Environment on Learning Efficiency in Different Types of Tasks: A 3 × 4 × 3 Full Factorial Design Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph15061256 ◽

2018 ◽

Vol 15 (6) ◽

pp. 1256 ◽

Cited By ~ 3

Author(s):

Lilin Xiong ◽

Xiao Huang ◽

Jie Li ◽

Peng Mao ◽

Xiang Wang ◽

...

Keyword(s):

Factorial Design ◽

Physical Environment ◽

Design Analysis ◽

Full Factorial Design ◽

Learning Efficiency ◽

Different Types ◽

Factorial Design Analysis ◽

Full Factorial

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A factorial design analysis of chitin production by Cunninghamella elegans

Canadian Journal of Microbiology ◽

10.1139/w00-086 ◽

2000 ◽

Vol 46 (11) ◽

pp. 1042-1045 ◽

Cited By ~ 3

Author(s):

V S Andrade ◽

B B Neto ◽

W Souza ◽

G M Campos-Takaki

Keyword(s):

Nmr Spectroscopy ◽

Factorial Design ◽

Culture Medium ◽

Design Analysis ◽

Full Factorial Design ◽

Cunninghamella Elegans ◽

Positive Effects ◽

Factorial Design Analysis ◽

Full Factorial

Chitin production by Cunninghamella elegans (IFM 46109) was studied with a two-level full factorial design, varying time of cultivation and the concentration of D-glucose, L-asparagine, and thiamine in the culture medium. The material extracted was characterized by infrared and NMR spectroscopy. The highest chitin yield, 28.8%, was comparable with the highest in the literature and was obtained with a medium containing 60 g·L-1 of glucose, 3 g·L-1 of asparagine, and 0.008 mg·L-1 of thiamine. Increasing the time of cultivation from 24 h to 72 h did not affect chitin production. The three factors showed significant positive effects on chitin production, without interactions between them.Key words: chitin, chitosan, zygomycetes, Cunninghamella elegans.

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