Comments on: “Predictors of adherence to exercise interventions during and after cancer treatment: A systematic review”

IntroductionCancer (and survival) is known to affect the quality of life. Strategies as physical activity and exercise during and after cancer may improve health-related qualify of life (HRQOL) outcomes and are, therefore, of clinical and public health importance. To the best of our knowledge, comparative evidence of the effect of the different types of exercise on improving HRQOL in cancer patients has not been synthesised thus far. We aim to conduct a systematic review and network meta-analysis in order to synthesise all available evidence regarding the effect of different types of exercise interventions on HRQOL during and after cancer treatment.Methods and analysisMEDLINE (via PubMed), Web of Science, Embase, The Cochrane Library and SPORTDiscus will be searched from inception to December 2018 for relevant randomised controlled trials (RCTs) and non-RCTs. Studies assessing physical activity and exercise interventions in cancer patients (during treatment) and survivors (after treatment) will be selected. Two independent reviewers will identify eligible studies. After quality appraisal and data extraction, we will conduct meta-analyses for outcomes of interest, including data from mental and physical dimensions of cancer-specific and/or generic HRQOL questionnaires. Risk of bias assessments will be completed using the Quality Assessment Tool for Quantitative Studies. Study heterogeneity will be measured by the I2 statistic. Bayesian (and traditional approach) network meta-analysis will be performed when possible to determine the comparative effect of the different physical activity or exercise interventions.Ethics and disseminationThis systematic review and network meta-analysis will synthesise evidence on the effect of different types of exercise interventions on HRQOL during and after cancer treatment. The results will be disseminated by publication in a peer-reviewed journal and through scientific conferences and symposia. Ethical approval will not be required because the data used for this work will be exclusively extracted from published studies.PROSPERO registration numberCRD42019125028.

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The Effect of Resistance Training on Body Composition During and After Cancer Treatment: A Systematic Review and Meta-Analysis

Sports Medicine ◽

10.1007/s40279-021-01542-6 ◽

2021 ◽

Author(s):

Briana Clifford ◽

Sean Koizumi ◽

Michael A. Wewege ◽

Hayley B. Leake ◽

Lauren Ha ◽

...

Keyword(s):

Systematic Review ◽

Body Composition ◽

Resistance Training ◽

Cancer Treatment ◽

Meta Analysis ◽

After Cancer

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Xenotransplantation of cryopreserved human ovarian tissue—a systematic review of MII oocyte maturation and discussion of it as a realistic option for restoring fertility after cancer treatment

Fertility and Sterility ◽

10.1016/j.fertnstert.2015.03.001 ◽

2015 ◽

Vol 103 (6) ◽

pp. 1557-1565 ◽

Cited By ~ 23

Author(s):

Ralf Dittrich ◽

Laura Lotz ◽

Tanja Fehm ◽

Jan Krüssel ◽

Michael von Wolff ◽

...

Keyword(s):

Systematic Review ◽

Cancer Treatment ◽

Oocyte Maturation ◽

Ovarian Tissue ◽

Human Ovarian Tissue ◽

Realistic Option ◽

After Cancer

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Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis

British Journal of Sports Medicine ◽

10.1136/bjsports-2016-096422 ◽

2017 ◽

Vol 52 (10) ◽

pp. 651-658 ◽

Cited By ~ 62

Author(s):

Roger Hilfiker ◽

Andre Meichtry ◽

Manuela Eicher ◽

Lina Nilsson Balfe ◽

Ruud H Knols ◽

...

Keyword(s):

Systematic Review ◽

Resistance Training ◽

Cancer Treatment ◽

Meta Analysis ◽

Cancer Type ◽

Cancer Related Fatigue ◽

Different Types ◽

After Cancer ◽

Indirect Comparisons ◽

Pharmaceutical Interventions

AimTo assess the relative effects of different types of exercise and other non-pharmaceutical interventions on cancer-related fatigue (CRF) in patients during and after cancer treatment.DesignSystematic review and indirect-comparisons meta-analysis.Data sourcesArticles were searched in PubMed, Cochrane CENTRAL and published meta-analyses.Eligibility criteria for selecting studiesRandomised studies published up to January 2017 evaluating different types of exercise or other non-pharmaceutical interventions to reduce CRF in any cancer type during or after treatment.Study appraisal and synthesisRisk of bias assessment with PEDro criteria and random effects Bayesian network meta-analysis.ResultsWe included 245 studies. Comparing the treatments with usual care during cancer treatment, relaxation exercise was the highest ranked intervention with a standardisedmean difference (SMD) of −0.77 (95% Credible Interval (CrI) −1.22 to −0.31), while massage (−0.78; −1.55 to −0.01), cognitive–behavioural therapy combined with physical activity (combined CBT, −0.72; −1.34 to −0.09), combined aerobic and resistance training (−0.67; −1.01 to −0.34), resistance training (−0.53; −1.02 to −0.03), aerobic (−0.53; −0.80 to −0.26) and yoga (−0.51; −1.01 to 0.00) all had moderate-to-large SMDs. After cancer treatment, yoga showed the highest effect (−0.68; −0.93 to −0.43). Combined aerobic and resistance training (−0.50; −0.66 to −0.34), combined CBT (−0.45; −0.70 to −0.21), Tai-Chi (−0.45; −0.84 to −0.06), CBT (−0.42; −0.58 to −0.25), resistance training (−0.35; −0.62 to −0.08) and aerobic (−0.33; −0.51 to −0.16) showed all small-to-moderate SMDs.ConclusionsPatients can choose among different effective types of exercise and non-pharmaceutical interventions to reduce CRF.

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