Smooth muscle relaxant activities of compounds isolated from malaysian medicinal plants on rat aorta and guinea-pig ileum

1995 ◽  
Vol 9 (8) ◽  
pp. 555-558 ◽  
Author(s):  
Mohd. Rais Mustafa ◽  
Rohaini Mohamad ◽  
Laily Din ◽  
Shamsuddin Wahid
2006 ◽  
Vol 1 (8) ◽  
pp. 1934578X0600100
Author(s):  
Janne Rojas Vera ◽  
Christopher G. Dacke ◽  
Asmita V. Patel ◽  
Gerald Blunden

A methanol extract of Rubus idaeus leaves was fractionated by column chromatography and the eluted samples were tested for their ability to relax transmurally stimulated Guinea pig ileum preparations in vitro. Two distinct bands of activity were detected. From band one sitosterol and eight triterpenoids were characterized, but only olean-18-ene-1β, 2α, 3α-triol demonstrated smooth muscle relaxant activity. This compound is, to the best of our knowledge, novel, as are olean-12-ene-3β, 29-diol and urs-12-ene-3β, 30-diol.


Planta Medica ◽  
2005 ◽  
Vol 71 (4) ◽  
pp. 320-325 ◽  
Author(s):  
Blanca Rivero-Cruz ◽  
María Alejandra Rojas ◽  
Rogelio Rodríguez-Sotres ◽  
Carlos M. Cerda-García-Rojas ◽  
Rachel Mata

1993 ◽  
Vol 238 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Charles M. Pedersen ◽  
Steffen Thirstrup ◽  
Jens Erik Nielsen-Kudsk

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