A Chinese Herbal Decoction, Danggui Buxue Tang, Improves Chronic Fatigue Syndrome Induced by Food Restriction and Forced Swimming in Rats

2011 ◽  
Vol 25 (12) ◽  
pp. 1825-1832 ◽  
Author(s):  
Ya Liu ◽  
Hai-Gang Zhang ◽  
Xiao-Hui Li
2021 ◽  
Vol 3 (4) ◽  
pp. 01-05
Author(s):  
Dan Jiang

The coronavirus disease 2019 (COVID-19) has still been spreading around the world, causing an outbreak of acute infectious pneumonia, even a multiple systematic inflammatory disorders following with varied virus. From World Health Organizations (WHO) weekly report in 16th Aug 2021, more than 2 hundred millions (206 693 357) of infected cases and more than 4 million (4 352 488) of deaths are confirmed in the world [1]. The daily report In UK in 18th Aug 2021, there are more than 6 million of infected cases (6 295 613) and 130 thousands of died cases (130 979) are confirmed, fluctuating figures on daily recently on infected and died cases with Covid-19 are reported although the severe case rates, hospitalized rates and died rate have decreased in UK [2]. Due to such bigger amount of patients’ appearance, some post-syndrome of Covid-19 are unavoidably leaving after they are self-healed or treated in the hospitals or anywhere else, they have not recovered completely, still remain some unwanted symptoms, some of them can be quite serious which are possible to disturb them for the rest of their life. We should do and be able doing some significant helps for them with Chinese herbal medicine (TCM). I will discuss these common occurrences of post- syndromes which I have treated: inferior function of lungs, dysfunction of gastrointestinal system, Psychiatric disorder, Post-virus-Chronic-fatigue syndrome, post inflammation of Sexual organs and how manage these post syndromes of Covid-19 with TCM here. TCM should play more effect for helping post-syndromes of Covid-19 after reopening clinics with full of our treating technologies.


2019 ◽  
Vol 37 (4) ◽  
pp. 211-222 ◽  
Author(s):  
Qing Zhang ◽  
Jing Gong ◽  
Haoxu Dong ◽  
Shabei Xu ◽  
Wei Wang ◽  
...  

Objective: To evaluate evidence for the efficacy of acupuncture for chronic fatigue syndrome (CFS). Methods: Randomized controlled trials (RCTs) comparing acupuncture with sham acupuncture, other interventions that may have a therapeutic effect, or no intervention, for the treatment of CFS, were searched for in the following databases up to March 2018: Pubmed; Embase; the Cochrane Library; Web of Science; Wanfang database; China National Knowledge Infrastructure (CNKI); Chinese Biomedicine (CBM) database; and VIP database. Risk of bias was determined using the Cochrane tool. Meta-analyses were performed using RevMan V.5.3 software. The GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) was adopted for levels of evidence. Results: Sixteen studies with 1346 subjects were included. Most studies had low methodological quality. Meta-analyses showed a favourable effect of acupuncture on overall response rate compared with sham acupuncture (four studies, 281 participants, RR=2.08, 95% CI 1.4 to 3.1, I2=64%, low certainty) and Chinese herbal medicine (three studies, 290 participants, RR=1.17, 95% CI 1.07 to 1.29, I2=0%, low certainty). Acupuncture also appeared to significantly reduce fatigue severity measured by Chalder’s Fatigue Scale and the Fatigue Severity Scale compared with other types of control. Conclusion: Our review indicated that acupuncture was more effective than sham acupuncture and other interventions (Chinese herbal medicine, mainly), but no firm conclusion could be reached owing to limited data, poor quality and potentially exaggerated effect size evaluation. Further large, rigorously designed and reported RCTs are required.


2019 ◽  
Vol 42 (7) ◽  
pp. 1140-1145 ◽  
Author(s):  
Takuya Ohba ◽  
Shinichi Domoto ◽  
Miyu Tanaka ◽  
Shinsuke Nakamura ◽  
Masamitsu Shimazawa ◽  
...  

2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Fangnan Wu ◽  
Chaolu Huder ◽  
Zhenjun Tian

Objective To investigate the effects of exogenous VD3 on exercise-induced chronic fatigue syndrome (CFS) and its mechanism. Methods 80 male mice were randomly divided into 5 groups(n=16). One group was named as quiet control group (C) while the other four were used to build CFS model by forced swimming. Among the four groups, three were selected for feeding VD3 1 h before exercise (bVD), 15 min after starting exercise (mVD) and 1 h after exercise (aVD) respectively, and the group without VD3 feeding was CFS model group (CFS). The behavior and condition of mice was observed during the whole process. After the training was completed totally, the tail suspension test and the forced swimming test were implemented, and then the blood and quadriceps were dissected. Serum testosterone and corticosterone content, as well as the antioxidant system indexes in the quadriceps, including malondialdehyde (MDA), total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-PX) and total superoxide dismutase (T-SOD), were measured. Routine western blotting experimentation was used to measure signal pathway indicators, containing SIRT1, SIRT3, ERK1/2, p-ERK1/2 and MEK1/2. Results Compared with C group, CFS group appeared serious damage caused by fighting, and the concentration of serum testosterone decreased significantly (p<0.01 or p<0.05) while cortisol concentration increased significantly (p<0.01 or p<0.05). Regarding antioxidant stress system indexes, the expression of MDA, T-SOD and GSH-PX significantly increased (p<0.05). The concentration of MEK and SIRT3 decreased significantly (p<0.01 or p<0.05). Compared with CFS group, VD intervention group (bVD, mVD and aVD) showed less damage caused by fighting and significantly lighter body weight (p<0.05), and the concentration of serum testosterone increased significantly (p<0.05) while that of cortisol decreased significantly (p<0.01 or p<0.05). The expression of MDA decreased significantly (p<0.05), on the countrary, T-AOC, T-SOD and GSH-PX increased significantly (p<0.05). The expressions of MEK, p-ERK/ERK, SIRT1 and SIRT3 were significantly upregulated (p<0.01 or p<0.05). Conclusions Exogenous VD3 could alleviate CFS, which probably related to activate the MEKs/ERKs-SIRT1 signal transduction axis and hence regulate the expression of SIRT3.


1999 ◽  
Vol 97 (3) ◽  
pp. 319 ◽  
Author(s):  
D.A. DUPREZ ◽  
M.L. DE BUYZERE ◽  
B. DRIEGHE ◽  
F. VANHAVERBEKE ◽  
Y. TAES ◽  
...  

2017 ◽  
Vol 33 (3) ◽  
pp. 158-165
Author(s):  
Natalia Calvo ◽  
Naia Sáez-Francàs ◽  
Sergi Valero ◽  
Jesús Castro-Marrero ◽  
José Alegre Martín ◽  
...  

Abstract. The study examines the relationship between a categorical and a dimensional personality assessment instrument in patients with Chronic Fatigue Syndrome (CFS). A total of 162 CFS patients were included in the study (91.4% women; mean age 47.5 years). All subjects completed the Spanish versions of the Personality Diagnostic Questionnaire-4+ (PDQ-4+) and the Temperament and Character Inventory-Revised (TCI-R). Results: 78 (48.1%) of the patients presented a Personality Disorder (PD), the most frequent being Cluster C, specifically Obsessive-compulsive disorder, followed by Avoidant disorder. PDs showed a specific pattern of correlation with temperament scales. All PD clusters correlated positively with Harm Avoidance and Self-Transcendence, and negatively with Reward Dependence, Self-Directedness, and Cooperativeness. In a logistic regression analysis, Self-Directedness and Cooperativeness predicted PD presence. The findings are consistent with previous studies in non-CFS samples and suggest that the combination of the Temperament and Character dimensions (low Self-Directedness and Cooperativeness and high Harm Avoidance and Self-Transcendence) correlates with PD severity, and that Self-Directedness and Cooperativeness are associated with PD presence in CFS patients. The integration of these two perspectives expands the current comprehension of personality pathology in CFS patients.


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