Structural characterization of bioactive compounds in Cotula cinerea extracts by ultra‐high‐performance liquid chromatography with photodiode array and high‐resolution time‐of‐flight mass spectrometry detectors

2020 ◽  
Vol 34 (8) ◽  
Author(s):  
Fatima‐Ezzahrae Guaouguaou ◽  
Mohamed Alien Ahl Bebaha ◽  
Sudhakar Yadlapalli ◽  
Khalid Taghzouti ◽  
Nour Eddine Es‐Safi
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Resolution ◽  
High Performance ◽  
Resolution Time ◽  
Flight Mass Spectrometry ◽  
Photodiode Array ◽  
Cotula Cinerea

scholarly journals High performance liquid chromatography coupled with high resolution mass spectrometry-based characterization of lipidomic responses from rats with kidney injuries

RSC Advances ◽  
2018 ◽  
Vol 8 (36) ◽  
pp. 20250-20258
Author(s):  
Qun Liang ◽  
Han Liu ◽  
Xiuli Li ◽  
Yang Zhang
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Lipid Metabolism ◽  
High Resolution ◽  
High Performance ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
Resolution Mass

In this study, we present targeted and non-targeted lipidomics strategies to discover the lipid metabolism variation in serum in rats with sepsis-induced kidney injuries.

Rapid Detection and Characterization of Steroidal Saponins in the Root of Asparagus cochinchinensis by High-Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry

2020 ◽  
Vol 58 (5) ◽  
pp. 454-463
Author(s):  
Yun Ling ◽  
Xin He ◽  
Renliang Jiang ◽  
Qi Zhang ◽  
Shuqin Yuan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
High Performance ◽  
Time Of Flight ◽  
Steroidal Saponins ◽  
Flight Mass Spectrometry ◽  
Asparagus Cochinchinensis

Abstract The dried root of Asparagus cochinchinensis (RAC) has been used as an important traditional Chinese medicine for a long time in China. Steroidal saponins (SSs) are considered to be the main active ingredients of this herb. However, the isolation and structural determination of SSs from RAC are time-consuming and laborious. For this reason, the development of new methods for the separation and characterization of SSs is highly desirable. In this study, a new high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method with precursor ions and the corresponding fragment ions was developed for the identification of SSs in RAC. Finally, 30 SSs have been detected and identified, including 17 potential new compounds. This is the first systematic study of SSs in RAC by HPLC-ESI-QTOF-MS/MS method.

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