Rapid screening procedures for a variety of complex forensic samples using a Laser Diode Thermal Desorption (LDTD) coupled to different mass spectrometers

2022 ◽  
Author(s):  
Eshwar Jagerdeo ◽  
Serge Auger
Keyword(s):  
Thermal Desorption ◽  
Laser Diode ◽  
Rapid Screening ◽  
Mass Spectrometers ◽  
Forensic Samples ◽  
Screening Procedures

Development of a simple and rapid screening method for the detection of 1-(3-chlorophenyl)piperazine in forensic samples

Talanta ◽  
2021 ◽  
pp. 122597
Author(s):  
Weberson P. Silva ◽  
Raquel G. Rocha ◽  
Luciano C. Arantes ◽  
Camila D. Lima ◽  
Larissa M.A. Melo ◽  
...  
Keyword(s):  
Screening Method ◽  
Rapid Screening ◽  
Forensic Samples ◽  
Rapid Screening Method

scholarly journals Rapid screening of pharmaceutical drugs using thermal desorption – SALDI mass spectrometry

2012 ◽  
Vol 398 ◽  
pp. 012033 ◽  
Author(s):  
A A Grechnikov ◽  
A E Kubasov ◽  
V B Georgieva ◽  
A S Borodkov ◽  
S M Nikiforov ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Thermal Desorption ◽  
Rapid Screening ◽  
Pharmaceutical Drugs

Rapid Determination of Chloramphenicol in Honey by Laser Diode Thermal Desorption Using Atmospheric Pressure Chemical Ionization-Tandem Mass Spectrometry

2013 ◽  
Vol 96 (3) ◽  
pp. 676-679 ◽  
Author(s):  
Grégory Blachon ◽  
Pierre Picard ◽  
Patrice Tremblay ◽  
Sarah Demers ◽  
Réal Paquin ◽  
...  
Keyword(s):  
Thermal Desorption ◽  
Laser Diode ◽  
Atmospheric Pressure ◽  
Chemical Ionization ◽  
Atmospheric Pressure Chemical Ionization ◽  
Rapid Determination ◽  
Internal Standard ◽  
Honey Sample ◽  
Pressure Chemical Ionization ◽  
Pressure Chemical

Abstract A high-throughput, rapid, and reliable method based on laser diode thermal desorption (LDTD) and atmospheric pressure chemical ionization coupled to tandem MS (APCI-MS/MS) was used to identify and quantify chloramphenicol (CAP) residues in honey. Sample pretreatment consisted of a liquid–liquid extraction of diluted honey in water with ethyl acetate containing stearic acid. After extraction, a 2 μL aliquot of the organic phase was deposited into a 96-well plate prior to detection by LDTD-APCI-MS/MS. The total analysis time was less than 6 s compared to several minutes for traditional chromatographic methods used for CAP detection, since no chromatographic separation was necessary. The extraction and analysis were made with honey samples of different color grading ranging from extra white to dark amber. The method showed good linearity (R2 = 0.99995) within a concentration range of 0.1 to 500 ng/g for CAP with D5-CAP as an internal standard. The RSD varied between 8 and 24% over the calibration range (n = 4). The method LOD for CAP in honey was 0.19 ng/g. This work demonstrates that LDTD-APCI-MS/MS could be used for fast and effective quantification of CAP in honey samples.

scholarly journals Pulsed Blue Laser Diode Thermal Desorption Microplasma Imaging Mass Spectrometry

2021 ◽  
Author(s):  
Alexander Knodel ◽  
Ulrich Marggraf ◽  
Edeltraut Hoffmann-Posorske ◽  
Sebastian Burhenn ◽  
Sebastian Brandt ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Thermal Desorption ◽  
Laser Diode ◽  
Imaging Mass Spectrometry ◽  
Blue Laser ◽  
Blue Laser Diode

scholarly journals Performance Evaluation of Thermal Desorption System (TDS) for Detection of Basic Drugs in Forensic Samples by GC-MS

2006 ◽  
Vol 30 (8) ◽  
pp. 581-592 ◽  
Author(s):  
J. A. Crifasi ◽  
M. F. Bruder ◽  
C. W. Long ◽  
K. Janssen
Keyword(s):  
Performance Evaluation ◽  
Thermal Desorption ◽  
Basic Drugs ◽  
Forensic Samples

Signal enhancement in laser diode thermal desorption-triple quadrupole mass spectrometry analysis using microwell surface coatings

2019 ◽  
Vol 54 (2) ◽  
pp. 167-177 ◽  
Author(s):  
Annick Dion-Fortier ◽  
Alexia Gravel ◽  
Cassandra Guérette ◽  
Fanny Chevillot ◽  
Sonia Blais ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Thermal Desorption ◽  
Laser Diode ◽  
Signal Enhancement ◽  
Surface Coatings ◽  
Mass Spectrometry Analysis ◽  
Triple Quadrupole ◽  
Quadrupole Mass ◽  
Spectrometry Analysis ◽  
Quadrupole Mass Spectrometry
Sign in / Sign up

Export Citation Format

Share Document