scholarly journals A rare case of lung squamous cell carcinoma coexisting with pulmonary MALT lymphoma presenting as a progressive pGGN

2020 ◽  
Vol 8 (7) ◽  
Author(s):  
Li Yang ◽  
Ting Wang ◽  
Mingjian Ge ◽  
Min Zhang ◽  
Youde Cao ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Malt Lymphoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Lung Squamous Cell Carcinoma ◽  
Pulmonary Malt Lymphoma

scholarly journals A Rare Case of a Metastatic Lung Squamous Cell Carcinoma to the Large Bowel and the Liver

Cureus ◽  
2021 ◽  
Author(s):  
Nikolaos Pararas ◽  
Georgios Kirkilessis ◽  
Andreas Pikoulis ◽  
Konstantinos Syrigos ◽  
Emmanouil Pikoulis
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Large Bowel ◽  
Rare Case ◽  
Lung Squamous Cell Carcinoma ◽  
Metastatic Lung

scholarly journals Isolated distal ulnar bone metastasis from lung squamous cell carcinoma: an extremely rare case report

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199887
Author(s):  
Kuei-Lin Yeh ◽  
Szu-Hsien Wu ◽  
Shing-Sheng Wu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Bone Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Bone Scan ◽  
Rare Case ◽  
Tumor Resection ◽  
Lung Squamous Cell Carcinoma ◽  
Rare Case Report

Bone metastases commonly occur in patients with lung cancer. However, metastasis from primary lung carcinoma to the bone below the knee and elbow is rarely encountered. We herein describe a man who developed an isolated distal ulnar bone metastasis originating from lung squamous cell carcinoma. A 68-year-old man presented to our orthopedic outpatient clinic for evaluation of a rapidly progressing tumor over his right wrist area. Tenderness with increased local temperature was noted, and the tumor was firm in consistency, oval-shaped, and 7 × 5 cm in size. Magnetic resonance imaging and radiographic imaging revealed an osteolytic tumor in his distal ulnar shaft. A 99m Tc-phosphate bone scan showed that this tumor was isolated and newly observed compared with the previous bone scan findings during initial diagnosis. Bone tumor biopsy confirmed metastatic squamous cell carcinoma. Segmental tumor resection with cementation was subsequently performed. This rare case report of an isolated ulnar metastasis includes detailed descriptions of the clinical, radiographic, and pathological features of the tumor.

scholarly journals Lung squamous cell carcinoma with brachial soft tissue metastasis responsive to gefitinib: Report of a rare case

2016 ◽  
Vol 7 (6) ◽  
pp. 676-680
Author(s):  
Kana Kataoka ◽  
Eiji Osaka ◽  
Tetsuo Shimizu ◽  
Yuki Okamura ◽  
Yukihiro Yoshida ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Soft Tissue ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Lung Squamous Cell Carcinoma ◽  
Soft Tissue Metastasis

PD-1 and PD-L1 Related Comprehensive Analysis of Lung Squamous Cell Carcinoma

2018 ◽  
Author(s):  
Guoping Li ◽  
Junyi Wang ◽  
Xi Dai ◽  
Dehong Wu ◽  
Xiang He ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Comprehensive Analysis

Comprehensive Molecular Characterizations of Chinese Patients with Different Subtypes of Lung Squamous Cell Carcinoma

2020 ◽  
Author(s):  
Jie Qian ◽  
Rongrong Chen ◽  
Ruiying Zhao ◽  
Yuchen Han ◽  
Yongfeng Yu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Chinese Patients

Investigation of Targeting Relationship between Micro-Rna-22 and Vegfr3 in Lung Squamous Cell Carcinoma

2020 ◽  
Vol 23 ◽  
Author(s):  
Zheng Dong ◽  
Qing-Hua Xu ◽  
Yuan-Bin Zhu ◽  
Yong-Feng Wang ◽  
Jie Xiong ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Luciferase Reporter ◽  
Control Group ◽  
Vascular Endothelial ◽  
Luciferase Reporter Gene ◽  
Endothelial Growth Factor

Aims : The present study explored the clinical significance of microRNA-22 (miR-22) expression in lung squamous cell carcinoma and to explore the targeting relationship with vascular endothelial growth factor receptor 3 (VEGFR3). Methods: A total of 49 patients with lung squamous cell carcinoma who underwent surgical treatment was selected. The expression of miR-22 was detected by fluorescence quantitative real-time PCR (qPCR), the expression of VEGFR3 was detected by Western blotting assays, and D240 labeled microlymphatic vessels density (MLVD) was detected immunohistochemistry (IHC). Lung squamous cell carcinoma cell line SK-MES-1 was selected and the targeting relationship between miR-22 and VEGFR3 was analyzed by double luciferase reporter gene assay. Western blotting assays were used to detect the expression of vascular endothelial growth factor-D (VEGF-D) and D240 in the blank control group, empty vector transfection group, miR-22 transfection group, miR-22 and VEGFR3 co-transfection group. Results: The expression range of miR-22 in lung squamous cell carcinoma was 0.8-3.5. The expression of miR-22 in lung squamous cell carcinoma was significantly different by tumor maximum diameter, lymph node metastasis, vascular invasion and TNM stage. The expression of miR-22 was linked to survival time. There was a negative correlation between miR-22 and VEGFR3, miR-22 and MLVD. Double luciferase reporter gene assays showed that miR-22 reduced the luciferase activity of pGL3-VEGFR3-WT transfected cells. Compared with the control group, the expression of VEGF-D and D2-40 in the miR-22 transfection group was significantly decreased. However, VEGF-D and D240 in the miR-22 and VEGFR3 cotransfection group reversed the changes. Conclusion: We assumed that the abnormal expression of miR-22 in lung squamous cell carcinoma may be involved in the development and progression of lung squamous cell carcinoma. MiR-22 negatively regulated the target gene VEGFR3 to mediate lymphangiogenesis. The expression of miR-22 may also be linked to the prognosis of the disease.

scholarly journals Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents

Oncotarget ◽  
2016 ◽  
Vol 8 (12) ◽  
pp. 18885-18900 ◽  
Author(s):  
Donghai Xiong ◽  
Jing Pan ◽  
Qi Zhang ◽  
Eva Szabo ◽  
Mark Steven Miller ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Mouse Lung ◽  
Chemopreventive Agents ◽  
Gene Expression Signatures
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