Birth order and oral clefts: A meta analysis

Teratology ◽  
2002 ◽  
Vol 66 (5) ◽  
pp. 209-216 ◽  
Author(s):  
Alexandre R. Vieira ◽  
I�da M. Orioli
Keyword(s):  
Birth Order ◽  
Meta Analysis ◽  
Oral Clefts

scholarly journals The Fraternal Birth-Order Effect as Statistical Artefact: Convergent Evidence from Probability Calculus, Simulated Data, and Multiverse Meta- Analysis

2021 ◽  
Author(s):  
Johannes K Vilsmeier ◽  
Michael Kossmeier ◽  
Martin Voracek ◽  
Ulrich S. Tran
Keyword(s):  
Sexual Orientation ◽  
Birth Order ◽  
Meta Analysis ◽  
Order Effect ◽  
Probability Calculus ◽  
Older Brothers ◽  
Birth Order Effect ◽  
Fraternal Birth Order ◽  
Fraternal Birth Order Effect ◽  
Ratio Variables

For a quarter of a century researchers investigating the origins of sexual orientation have largely ascribed to the fraternal birth order effect (FBOE) as a fact, holding that older brothers increase the odds of homosexual orientation among men through an immunoreactivity process. Here, we triangulate the empirical foundations of the FBOE from three distinct, informative perspectives: First, drawing on basic probability calculus, we deduce mathematically that the body of statistical evidence of the FBOE rests on the false assumptions that effects of family size should be controlled for and that this could be achieved through the use of ratio variables. Second, using a data-simulation approach, we demonstrate that by using ratio variables, researchers are bound to falsely declare corroborating evidence of an excess of older brothers at a rate of up to 100%, and that valid approaches attempting to quantify a potential excess of older brothers among homosexual men must control for the confounding effects of the number of older siblings. And third, we re-examine the empirical evidence of the FBOE by using a novel specification-curve and multiverse approach to meta-analysis. This yielded highly inconsistent and moreover similarly-sized effects across 64 male and 17 female samples (N = 2,778,998), compatible with an excess as well as with a lack of older brothers in both groups, thus, suggesting that almost no variation in the number of older brothers in men is attributable to sexual orientation.

SYSTEMATIC REVIEW AND META-ANALYSIS SHOW POTENTIAL GENETIC MARKERS FOR NONSYNDROMIC ORAL CLEFTS IN BRAZILIANS

2020 ◽  
Vol 130 (3) ◽  
pp. e239
Author(s):  
RENATO ASSIS MACHADO ◽  
ISABELA PORTO DE TOLEDO ◽  
HERCíLIO MARTELLI-JÚNIOR ◽  
SILVIA REGINA REIS ◽  
ELIETE NEVES SILVA GUERRA ◽  
...  
Keyword(s):  
Systematic Review ◽  
Genetic Markers ◽  
Meta Analysis ◽  
Oral Clefts

Birth order and number of siblings and their association with overweight and obesity: a systematic review and meta-analysis

2018 ◽  
Vol 76 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Fernanda Oliveira Meller ◽  
Christian Loret de Mola ◽  
Maria Cecília Formoso Assunção ◽  
Antônio Augusto Schäfer ◽  
Darren Lawrence Dahly ◽  
...  
Keyword(s):  
Systematic Review ◽  
Birth Order ◽  
Meta Analysis ◽  
Overweight And Obesity

Parental age as a risk factor for non-syndromic oral clefts: A meta-analysis

2012 ◽  
Vol 40 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Ana Paula Corrêa de Queiroz Herkrath ◽  
Fernando José Herkrath ◽  
Maria Augusta Bessa Rebelo ◽  
Mario Vianna Vettore
Keyword(s):  
Risk Factor ◽  
Meta Analysis ◽  
Parental Age ◽  
Oral Clefts

scholarly journals Folic acid–containing supplement consumption during pregnancy and risk for oral clefts: A meta-analysis

2007 ◽  
Vol 79 (1) ◽  
pp. 8-15 ◽  
Author(s):  
Rachel L. Badovinac ◽  
Martha M. Werler ◽  
Paige L. Williams ◽  
Karl T. Kelsey ◽  
Catherine Hayes
Keyword(s):  
Folic Acid ◽  
Meta Analysis ◽  
Oral Clefts

Prevalence of Dental Anomalies in Nonsyndromic Individuals with Cleft Lip and Palate: A Systematic Review and Meta-analysis

2012 ◽  
Vol 49 (2) ◽  
pp. 194-200 ◽  
Author(s):  
Patricia Nivoloni Tannure ◽  
Cristiana Aroeira G.R. Oliveira ◽  
Lucianne Copie Maia ◽  
Alexandre R. Vieira ◽  
José Mauro Granjeiro ◽  
...  
Keyword(s):  
Random Effects ◽  
Fixed Effects ◽  
Cleft Lip And Palate ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Permanent Teeth ◽  
Cochrane Library ◽  
Tooth Agenesis ◽  
Dental Anomalies ◽  
Oral Clefts

Objective To assess whether individuals born with nonsyndromic oral clefts display a higher frequency of dental anomalies. Design A search of MEDLINE, BIREME, OVID ALL EMB Reviews, and The Cochrane Library was conducted. The methodologic quality of the papers selected was assessed and scored. Papers reporting observational controlled studies of nonsyndromic forms of oral cleft matched for dental anomalies in primary and/or permanent teeth were included without language restrictions. Eligible studies were scored as “A”—low risk of bias, “B”—moderate risk of bias, or “C”—high risk of bias and poor quality. Fixed and random effects models were used to aggregate individual odds ratios (OR) and to derive pooled estimates and 95% confidence intervals. Results Six studies fulfilled our selection criteria and were included in the meta-analysis. Three distinct subgroup analyses were carried out in terms of dental anomalies. In the tooth agenesis meta-analysis, a random effects model was used because of heterogeneity and showed a significant association between tooth agenesis and oral clefts (OR = 12.31; 95% confidence interval [CI] = 3.75 to 40.36). In the remaining analyses, the fixed effects model revealed a positive association between supernumerary (OR = 4.99; 95% CI, 2.58 to 9.64) and crown morphologic abnormalities (OR = 5.69; 95% CI, 3.96 to 8.19) with oral clefts. Most included studies were of low to moderate quality. Conclusion Although general limitations in study design were observed, the evidence suggests that a higher number of dental anomalies in the permanent dentition are noted in individuals born with oral clefts.

Association of AXIN2 and CDH1 genes polymorphism with non syndromic Oral Clefts: A meta-analysis

Gene Reports ◽  
2021 ◽  
pp. 101424
Author(s):  
Paria Motahari
Keyword(s):  
Meta Analysis ◽  
Oral Clefts

Association between oral clefts and periodontal clinical measures: meta‐analysis

2021 ◽  
Author(s):  
Tamer Marzouk ◽  
Mostafa Youssef ◽  
Alexandra Tsigarida ◽  
Christy McKinney ◽  
Cynthia Wong ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Oral Clefts ◽  
Clinical Measures

Birth Order and Risk Taking in Athletics: A Meta-Analysis and Study of Major League Baseball

2010 ◽  
Vol 14 (4) ◽  
pp. 402-416 ◽  
Author(s):  
Frank J. Sulloway ◽  
Richard L. Zweigenhaft
Keyword(s):  
Birth Order ◽  
Risk Taking ◽  
Major League Baseball ◽  
Meta Analysis ◽  
Major League ◽  
Analysis And Study
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