Investigation into the sub‐lethal effects of the triazole fungicide triticonazole in zebrafish ( Danio rerio ) embryos/larvae

2019 ◽  
Vol 35 (2) ◽  
pp. 254-267 ◽  
Author(s):  
Christopher L. Souders ◽  
Veronica Perez‐Rodriguez ◽  
Nader El Ahmadie ◽  
Xujia Zhang ◽  
Claire Tischuk ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Lethal Effects ◽  
Triazole Fungicide ◽  
Danio Rerio Embryos

Sub-lethal effects of the triazole fungicide propiconazole on zebrafish (Danio rerio) development, oxidative respiration, and larval locomotor activity

2019 ◽  
Vol 74 ◽  
pp. 106809 ◽  
Author(s):  
Christopher L. Souders ◽  
Priscilla Xavier ◽  
Veronica Perez-Rodriguez ◽  
Naomi Ector ◽  
Ji-Liang Zhang ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Danio Rerio ◽  
Lethal Effects ◽  
Triazole Fungicide ◽  
Oxidative Respiration

scholarly journals Lethal and Sub-Lethal Effects and Modulation of Gene Expression Induced by T Kinase Inhibitors in Zebrafish (Danio Rerio) Embryos

Toxics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 4
Author(s):  
Tina Elersek ◽  
Matjaž Novak ◽  
Mateja Mlinar ◽  
Igor Virant ◽  
Nika Bahor ◽  
...  
Keyword(s):  
Imatinib Mesylate ◽  
Danio Rerio ◽  
Kinase Inhibitors ◽  
Lethal Effects ◽  
Expression Of Genes ◽  
Embryo Toxicity Test ◽  
Damage Response ◽  
Embryo Toxicity ◽  
Modulation Of Gene Expression ◽  
Danio Rerio Embryos

Tyrosine kinase inhibitors (TKIs) are designed for targeted cancer therapy. The consumption of these drugs during the last 20 years has been constantly rising. In the zebrafish (Danio rerio) embryo toxicity test, we assessed the toxicity of six TKIs: imatinib mesylate, erlotinib, nilotinib, dasatinib, sorafenib and regorafenib. Imatinib mesylate and dasatinib induced lethal effects, while regorafenib, sorfenib and dasatinib caused a significant increase of sub-lethal effects, predominantly oedema, no blood circulation and formation of blood aggregates. The analyses of the changes in the expression of selected genes associated with the hormone system after the exposure to imatinib mesylate, dasatinib and regorafenib demonstrated that all three tested TKIs deregulated the expression of oestrogen receptor esr1, cytochrome P450 aromatase (cypa19b) and hydroxysteroid-dehydrogenase (hsd3b), regorafenib, and also thyroglobulin (tg). The expression of genes involved in the DNA damage response (gadd45 and mcm6) and apoptosis (bcl2) was deregulated only by exposure to regorafenib. The data indicate that common mechanisms, namely antiangiogenic activity and interference with steroidogenesis are involved in the TKI induced sub-lethal effects and potential hormone disrupting activity, respectively. The residues of TKIs may represent an environmental hazard; therefore, further ecotoxicological studies focusing also on the effects of their mixtures are warranted.

Neurulation in the posterior region of zebrafish, Danio rerio embryos

2021 ◽  
Author(s):  
Julia Gladysheva ◽  
Evdokia Evnukova ◽  
Ekaterina Kondakova ◽  
Milana Kulakova ◽  
Vladimir Efremov
Keyword(s):  
Danio Rerio ◽  
Posterior Region ◽  
Danio Rerio Embryos

scholarly journals Gene co-expression network analysis reveals mechanisms underlying ozone-induced carbamazepine toxicity in zebrafish (Danio rerio) embryos

Chemosphere ◽  
2021 ◽  
Vol 276 ◽  
pp. 130282
Author(s):  
Johannes Pohl ◽  
Oksana Golovko ◽  
Gunnar Carlsson ◽  
Stefan Örn ◽  
Monika Schmitz ◽  
...  
Keyword(s):  
Network Analysis ◽  
Danio Rerio ◽  
Danio Rerio Embryos

91. Studies on impact of chilling on sox gene expression in zebrafish (Danio rerio) embryos

Cryobiology ◽  
2010 ◽  
Vol 61 (3) ◽  
pp. 389
Author(s):  
K.K. Desai ◽  
E. Spikings ◽  
D.M. Rawson ◽  
T. Zhang
Keyword(s):  
Gene Expression ◽  
Danio Rerio ◽  
Sox Gene ◽  
Danio Rerio Embryos

Short exposure to glyphosate induces locomotor, craniofacial, and bone disorders in zebrafish (Danio rerio) embryos

2021 ◽  
pp. 103700
Author(s):  
Rubén D. Díaz-Martín ◽  
Ana Carvajal-Peraza ◽  
Beatriz Yáñez-Rivera ◽  
Miguel Betancourt-Lozano
Keyword(s):  
Danio Rerio ◽  
Short Exposure ◽  
Bone Disorders ◽  
Danio Rerio Embryos

Effects of the brominated flame retardant, TBCO, on development of zebrafish (Danio rerio) embryos

Chemosphere ◽  
2021 ◽  
Vol 266 ◽  
pp. 129195
Author(s):  
Darren Van Essen ◽  
Chloe Devoy ◽  
Justin Miller ◽  
Paul D. Jones ◽  
Steve Wiseman
Keyword(s):  
Flame Retardant ◽  
Danio Rerio ◽  
Brominated Flame Retardant ◽  
Danio Rerio Embryos

Lethal effects of abamectin on the aquatic organisms Daphnia similis, Chironomus xanthus and Danio rerio

Chemosphere ◽  
2012 ◽  
Vol 86 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Andréa Novelli ◽  
Bruna Horvath Vieira ◽  
Daniela Cordeiro ◽  
Luciana Teresa Dias Cappelini ◽  
Eny Maria Vieira ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Aquatic Organisms ◽  
Lethal Effects ◽  
Daphnia Similis
Sign in / Sign up

Export Citation Format

Share Document