scholarly journals OC18.08: Developing a first trimester anomaly screening protocol for the UK: a consensus procedure

2021 ◽  
Vol 58 (S1) ◽  
pp. 54-55
Author(s):  
J. Karim ◽  
S. Gordijn ◽  
A.T. Papageorghiou
Keyword(s):  
First Trimester ◽  
Screening Protocol ◽  
Consensus Procedure ◽  
The Uk

scholarly journals Effleurage Massage for Pain Relief in Pregnant Women

2020 ◽  
Vol 2 (1) ◽  
pp. 185-197
Author(s):  
Mutia Nadra Maulida
Keyword(s):  
Back Pain ◽  
Pregnant Women ◽  
Varicose Veins ◽  
First Trimester ◽  
Maximum Point ◽  
Physiological Changes ◽  
Second Trimester ◽  
Third Trimester ◽  
The Uk ◽  
Spinal Muscles

Pregnancy is an event that begins with conception and ends with the onset of labor. Pregnancy is divided into three trimesters, the first trimester (0-12 weeks), the second trimester (13-27 weeks), and the third trimester (28-40 weeks). During the pregnancy process will cause various changes in all body systems, both physiological changes and psychological changes that can cause discomfort to pregnant women. Physiological changes that often occur in pregnant women such as dyspnea, insomnia, gingivitis, frequent urination, pressure and discomfort in the perineum, back pain, constipation, varicose veins, fatigue, Braxton hicks contractions, leg cramps, ankle edema. Not only physiologically, changes in pregnant women also occur psychologically such as changes in mood and increased anxiety.One of the physiological changes that pregnant women often complain about is back pain. According to Ratih (2016), the results of research on pregnant women in various regions of Indonesia reached 60-80% of people who experience back pain in their pregnancy. The reported prevalence of back pain in pregnancy varies from 50% in the UK and Scandinavia to 70% in Australia. Back pain experienced by pregnant women will peak at week 24 to week 28, just before abdominal growth reaches its maximum point. Most back pain during pregnancy occurs due to changes in the spinal muscles, as much as 70%.Back pain in pregnant women can be treated both pharmacologically and non pharmacologically. One of the non-pharmacological therapies that can be given is Effleurage Massage, which provides a gentle, slow and uninterrupted massage on the back of pregnant women so that it can cause relaxation and reduce pain.

The UK diabetic pregnancy survey

1986 ◽  
Vol 113 (3_Suppl) ◽  
pp. S86-S89 ◽  
Author(s):  
C. Lowy ◽  
R. W. Beard ◽  
J. Goldschmidt
Keyword(s):  
Blood Glucose ◽  
Maternal Diabetes ◽  
First Trimester ◽  
Blood Glucose Measurement ◽  
Glucose Measurement ◽  
Third Trimester ◽  
Gestational Age At Delivery ◽  
Insulin Dependent ◽  
First Trimester Of Pregnancy ◽  
The Uk

Abstract. A prospective, national survey of the UK which examined the management and outcome of pregnancy complicated by maternal diabetes is described. The perinatal mortality rate was 3.7 and 1.5 times greater than the overall UK rate and the malformation rate 6.4% and 1.9% in pregnancies where the mother had insulin-dependent and gestational diabetes respectively. In 57% of cases no blood glucose measurement was recorded in the first trimester of pregnancy. Significantly fewer malformed infants resulted from prenancies where a first trimester blood glucose was recorded, irrespective of the value. Second and third trimester blood glucose values did not predict malformation but correlated inversely with gestational age at delivery and this was the major factor predicting the outcome of pregnancy.

First trimester diagnosis of Inherited Metabolic Disease: Experience in the UK

1991 ◽  
Vol 14 (2) ◽  
pp. 128-133 ◽  
Author(s):  
G. T. N. Besley ◽  
E. P. Young ◽  
A. H. Fensom ◽  
A. Cooper
Keyword(s):  
Metabolic Disease ◽  
First Trimester ◽  
Inherited Metabolic Disease ◽  
Disease Experience ◽  
The Uk

scholarly journals Sonographic Evaluation of Fetal Cardiac Anatomy in the Late First Trimester

2019 ◽  
Vol 36 (2) ◽  
pp. 140-150
Author(s):  
Emily Hildebrand
Keyword(s):  
Heart Defects ◽  
Color Doppler ◽  
First Trimester ◽  
Nuchal Translucency ◽  
The United States ◽  
Image Correlation ◽  
Future Research ◽  
Early Screening ◽  
Screening Protocol ◽  
The Impact

Objective: Congenital heart defects (CHDs) are the most common cause of infant death in the United States. Severe, complex cardiac anomalies make up approximately half of the cases and carry significant morbidity and mortality. The purpose of this literature review was to define a CHD screening protocol to be used in the first trimester. Methods: Literature was pulled that discussed the impact of color Doppler and spatiotemportal image correlation on image quality, explored the benefits and limitations of early screening, and analyzed the risk of bioeffects to the developing fetus. Results: A simplified cardiac screening protocol has been shown to be a feasible addition to the first trimester nuchal translucency scan. Conclusion: Color Doppler and three-dimensional sonography can be utilized during the first trimester to evaluate the fetal heart for major anomalies between 11 weeks and 13 weeks 6 days. Recommendations for future research and guidance from accrediting bodies are provided.

scholarly journals An exploration of how women in the UK perceive the provision of care received in an early pregnancy assessment unit: an interpretive phenomenological analysis

BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e023579 ◽  
Author(s):  
Wendy Norton ◽  
Lynn Furber
Keyword(s):  
Early Pregnancy ◽  
Clinical Information ◽  
First Trimester ◽  
Phenomenological Analysis ◽  
Interpretive Phenomenological Analysis ◽  
Large Teaching Hospital ◽  
Assessment Unit ◽  
Small Set ◽  
Individualised Care ◽  
The Uk

ObjectiveThe objective of the study was to explore how women experience care within an early pregnancy assessment unit (EPAU) and how they are helped to understand, reconcile and make sense of their loss and make informed decisions about how their care will be managed following a first trimester miscarriage.DesignThis was a single centre, prospective qualitative study. An interpretive phenomenological analysis approach was used to interpret the participants’ meanings of their experiences. It is an ideographic approach that focuses in depth on a small set of cases to explore how individuals make sense of a similar experience.SettingAn EPAU in a large teaching hospital in the Midlands that provides care to women in their early pregnancy, including those experiencing pregnancy loss.ParticipantsA purposive sample of 10 women were recruited to this study. All of the women were either miscarrying at the time of this study or had miscarried within the previous few weeks.ResultsSix superordinate themes in relation to women’s experiences of miscarriage were identified: (1) the waiting game, (2) searching for information, (3) management of miscarriage: no real choice, (4) the EPAU environment, (5) communication: some room for improvement and (6) moving on.ConclusionsThis study found that improvements are required to ensure women and their partners receive a streamlined, informative, supportive and continuous package of care from the point they first see their general practitioner or midwife for support to being discharged from the EPAU. The provision of individualised care, respect for women’s opinions and appropriate clinical information is imperative to those experiencing miscarriage to help them gain a degree of agency within an unfamiliar situation and one in which they feel is out of their control.

scholarly journals SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021—Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing

2021 ◽  
Vol 9 (4) ◽  
pp. 677
Author(s):  
Ana Rita Goncalves Cabecinhas ◽  
Tim Roloff ◽  
Madlen Stange ◽  
Claire Bertelli ◽  
Michael Huber ◽  
...  
Keyword(s):  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Implementation Process ◽  
Amplicon Sequencing ◽  
Whole Genome ◽  
Early Introduction ◽  
Specific Pcr ◽  
Screening Protocol ◽  
First Results ◽  
The Uk

The rapid spread of the SARS-CoV-2 lineages B.1.1.7 (N501Y.V1) throughout the UK, B.1.351 (N501Y.V2) in South Africa, and P.1 (B.1.1.28.1; N501Y.V3) in Brazil has led to the definition of variants of concern (VoCs) and recommendations for lineage specific surveillance. In Switzerland, during the last weeks of December 2020, we established a nationwide screening protocol across multiple laboratories, focusing first on epidemiological and microbiological definitions. In January 2021, we validated and implemented an N501Y-specific PCR to rapidly screen for VoCs, which are then confirmed using amplicon sequencing or whole genome sequencing (WGS). A total of 13,387 VoCs have been identified since the detection of the first Swiss case in October 2020, with 4194 being B.1.1.7, 172 B.1.351, and 7 P.1. The remaining 9014 cases of VoCs have been described without further lineage specification. Overall, all diagnostic centers reported a rapid increase of the percentage of detected VOCs, with a range of 6 to 46% between 25 to 31 of January 2021 increasing towards 41 to 82% between 22 to 28 of February. A total of 739 N501Y positive genomes were analysed and show a broad range of introduction events to Switzerland. In this paper, we describe the nationwide coordination and implementation process across laboratories, public health institutions, and researchers, the first results of our N501Y-specific variant screening, and the phylogenetic analysis of all available WGS data in Switzerland, that together identified the early introduction events and subsequent community spreading of the VoCs.

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