OP07.04: Two cases of struma ovarii with initial ultrasonographic diagnosis of malignant ovarian tumour

We report a case of 34-year-old clinically asymptomatic woman who had been followed for 6 years for hyperthyroidism with thyroid stimulating hormone <0.006 uIU/mL, free T4 1.98 ng/mL, free T3 5.3 pg/mL, elevated thyroid stimulating immunoglobulin 1.70 IU/L, thyroid peroxidase antibody 38 IU/mL and thyroglobulin antibody 9.3 IU/mL. Radioiodine thyroid scan showed minimal uptake in both thyroid lobes (24-hour uptake was 0.3%). She subsequently underwent evaluation for lower abdominal pain and menstrual irregularities, which revealed a large left ovarian cyst measuring 15.9 cm × 10.8 cm × 13.2 cm and right-sided ovarian cyst measuring 2.7 cm × 3.3 cm × 3.5 cm. Laparoscopic bilateral ovarian cystectomy was performed and the final pathology revealed struma ovarii of the left ovarian cyst with the entire ovarian tumour made up of benign thyroid tissue. Thyroid function tests performed 3 months after surgical removal of struma ovarii showed euthyroidism. We present a rare case with detailed laboratory and immunological data before and after ovarian extirpation with resolution of hyperthyroidism associated with functional struma ovarii.

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A rare ovarian tumour, struma ovarii

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20160829 ◽

2016 ◽

pp. 1292-1294

Author(s):

Sindhura Inkollu ◽

Vandana Kanumury ◽

Murmu Dasharatha ◽

Padmaja Adusumilli

Keyword(s):

Ovarian Tumour ◽

Struma Ovarii

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Intraoperative Consultation (Frozen Section) in the Diagnosis of Ovarian Tumour

Bangladesh Medical Journal ◽

10.3329/bmj.v48i3.51795 ◽

2021 ◽

Vol 48 (3) ◽

pp. 34-38

Author(s):

Jannatul Ferdous ◽

Shiuly Chowdhury ◽

Ferdousy Begum ◽

Shabnam Akhter ◽

Sabera Khatun ◽

...

Keyword(s):

Frozen Section ◽

Preoperative Evaluation ◽

Cross Sectional Study ◽

Ovarian Tumour ◽

Cross Sectional ◽

Borderline Tumour ◽

Standard Data ◽

Extent Of Surgery ◽

Malignant Ovarian Tumour ◽

Medical University

Ovarian cancer is a devastating disease preoperative evaluation of the patients with an ovarian tumour is difficult. So frozen section biopsy of ovarian tumour is important to determine the extent of surgery. This retrospective cross-sectional study was carried out in the Department of Gynaecological Oncology, Bangabandhu Sheikh Mujib Medical University from August 2016 to July 2017 to determine the validity of frozen section biopsy in the diagnosis of ovarian tumour. Fifty cases of ovarian tumour underwent frozen section biopsy were included by purposive sampling. Histopathological finding was taken as the gold standard. Data was analyzed by SPSS version 16. The sensitivity of frozen section in the diagnosis of benign, borderline and malignant were 100%, 100% and 97.67% respectively as well as the specificities were 100%, 97.96% and 100% respectively. Similarly the accuracy, PPV, NPV for the benign, borderline and malignant ovarian tumour were also high except the borderline tumour which had low PPV. Bangladesh Med J. 2019 Sep; 48 (3): 34-38

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Combined malignant ovarian tumour consisting of angiosarcoma, adenosarcoma, cystadenofibroma and granulosa cell tumour

Journal of Obstetrics and Gynaecology ◽

10.1080/01443610701844002 ◽

2008 ◽

Vol 28 (1) ◽

pp. 121-123 ◽

Cited By ~ 4

Author(s):

I. Giarenis ◽

D. Peat ◽

J. J. Nieto

Keyword(s):

Granulosa Cell ◽

Ovarian Tumour ◽

Cell Tumour ◽

Granulosa Cell Tumour ◽

Malignant Ovarian Tumour

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D-DIMER AND FIBRINOGEN IN PATIENTS UNDERWENT SURGERY IN MALIGNANT AND BENIGN OVARIAN TUMOR (D-Dimer Dan Fibrinogen Pada Pasien-Pasien Yang Menjalani Tindakan Pembedahan Pada Tumor Ovarium Ganas Dan Jinak)

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY ◽

10.24293/ijcpml.v25i2.1288 ◽

2019 ◽

Vol 25 (2) ◽

pp. 184

Author(s):

Ismail Aswin ◽

Herman Hariman ◽

Fauzie Sahil

Keyword(s):

Ovarian Tumor ◽

Ovarian Tumour ◽

Rank Test ◽

Benign Ovarian Tumor ◽

Operation Procedure ◽

Increase Risk ◽

Malignant Ovarian Tumour ◽

Tumour Patient ◽

Benign Ovarian Tumour ◽

D Dimer

Ovarian tumour ranks second in gynecology tumour cases and ranks second in gynecology tumour death in Indonesia. Tumour cause hypercoagulable that increase risk of thrombosis by procoagulant mechanism. Tumout cells also can cause hyperfibrinogenemmia that can cause bleeding. The aim of study was to know D-dimer and fibrinogen value to investigate primary hyperfibrinolysis on malignant and benign ovarian tumour; and to know whether operation procedure on malignant and benign tumour change D-dimer and fibrinogen value. Prospective analysis study, subject were malignant and benign ovarian tumour patients undergoing surgery in Haji Adam Malik Hospital, Medan. One way Annova test dan Wilcoxon Sum-Rank test were performed. Stastical differentiation is indicate with p<0,05. Study subject was 16 patient where 8 malignant and benign ovarian tumour patient respectively. Malignant ovarian tumour D-dimer values was higher than benign ovarian tumour (p<0,01) that indicate fibrinolysis increase in malignant ovarian tumour. Malignant ovarian tumour fibrinogen values as same as benign ovarian tumour (p>0,05) that indicate the fibrinolysis in ovarian tumour wasn’t primary hyperfibrinolysis. Surgery procedure didn’t influence D-dimer and fibrinogen values. Primary hyperfibrinolysis wasn’t occur in ovarian tumour.Keywords : Ovarian tumour, malignant, benign, D-dimer, fibrinogen.

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