P10.01: Comparative study on quantitative parameters of blood perfusion and microvessel density in placenta of rat model of preeclampsia evaluted with contrast enhanced ultrasound

2010 ◽  
Vol 36 (S1) ◽  
pp. 205-205
Author(s):  
C. X. Xinlin ◽  
Y. Xu
Keyword(s):  
Comparative Study ◽  
Rat Model ◽  
Microvessel Density ◽  
Blood Perfusion ◽  
Contrast Enhanced Ultrasound ◽  
Quantitative Parameters ◽  
Contrast Enhanced

scholarly journals Correlation of radiomic features on dynamic contrast-enhanced magnetic resonance with microvessel density in hepatocellular carcinoma based on different models

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199758
Author(s):  
Hongwei Liang ◽  
Chunhong Hu ◽  
Jian Lu ◽  
Tao Zhang ◽  
Jifeng Jiang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Magnetic Resonance ◽  
Microvessel Density ◽  
Roc Analysis ◽  
Diagnostic Model ◽  
Model Parameters ◽  
Dce Mri ◽  
Dynamic Contrast Enhanced ◽  
Quantitative Parameters ◽  
Contrast Enhanced

Objective To explore the correlations of radiomic features of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with microvessel density (MVD) in patients with hepatocellular carcinoma (HCC), based on single-input and dual-input two-compartment extended Tofts (SITET and DITET) models. Methods We compared the quantitative parameters of SITET and DITET models for DCE-MRI in 30 patients with HCC using paired sample t-tests. The correlations of SITET and DITET model parameters with CD31-MVD and CD34-MVD were analyzed using Pearson’s correlation analysis. A diagnostic model of CD34-MVD was established and the diagnostic abilities of models for MVD were analyzed using receiver operating characteristic curve (ROC) analysis. Results There were significant differences between the quantitative parameters in the two kinds of models. Compared with SITET, DITET parameters showed better correlations with CD31-MVD and CD34-MVD. The Ktrans and Ve radiomics features of the DITET model showed high efficiency for predicting the level of CD34-MVD according to ROC analysis, with areas under curves of 0.83 and 0.94, respectively. Conclusion Compared with SITET, the DITET model provides a better indication of the microcirculation of HCC and is thus more suitable for examining patients with HCC.

scholarly journals Measuring Absolute Blood Perfusion in Mice Using Dynamic Contrast-Enhanced Ultrasound

2017 ◽  
Vol 43 (8) ◽  
pp. 1628-1638 ◽  
Author(s):  
Abbas Shirinifard ◽  
Suresh Thiagarajan ◽  
Melissa D. Johnson ◽  
Christopher Calabrese ◽  
András Sablauer
Keyword(s):  
Blood Perfusion ◽  
Contrast Enhanced Ultrasound ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced
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