Pulmonary artery stenosis versus supravalvular pulmonic stenosis: Correctly describing a congenital stenosis of the pulmonic outflow tract in a domestic cat

2021 ◽  
Author(s):  
Gurcharan Emily Chrai ◽  
P. Brent Lawson ◽  
Liza S. Köster
Keyword(s):  
Pulmonary Artery ◽  
Outflow Tract ◽  
Artery Stenosis ◽  
Domestic Cat ◽  
Pulmonary Artery Stenosis ◽  
Pulmonic Stenosis

Increased Airway Pressure and Simulated Branch Pulmonary Artery Stenosis Increase Pulmonary Regurgitation After Repair of Tetralogy of Fallot

Circulation ◽  
1997 ◽  
Vol 95 (3) ◽  
pp. 643-649 ◽  
Author(s):  
Rajiv R. Chaturvedi ◽  
Philip J. Kilner ◽  
Paul A. White ◽  
Andrew Bishop ◽  
Richard Szwarc ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Tetralogy Of Fallot ◽  
Airway Pressure ◽  
Pulmonary Regurgitation ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Branch Pulmonary Artery ◽  
Branch Pulmonary Artery Stenosis

scholarly journals Identification and characterization of a novel ELN mutation in congenital heart disease with pulmonary artery stenosis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cuilan Hou ◽  
Junmin Zheng ◽  
Wei liu ◽  
Lijian Xie ◽  
Xiaomin Sun ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Artery ◽  
Molecular Mechanism ◽  
Protein Level ◽  
Congenital Heart ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Functional Component ◽  
Functional Changes

AbstractCongenital heart defects, one of the most common birth defects, affect approximately 1% of live birth globally and remain the leading cause of infant mortality in developed countries. Utilizing the pathogenicity score and inheritance mode from whole exome sequencing results, a heterozygous mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) in elastin (ELN) was identified among 6,440 variants in a female proband born with an atrial septal defect accompanied by pulmonary artery stenosis. Results of RT-PCR showed that the mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) did not affect the expression levels of ELN mRNA but increased protein level. The content of ELN truncate (functional component) was significantly lower in both the intracellular and extracellular compartments after mutation. These results indicate that the ELN mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) affected the protein truncate, which may be a functional component of ELN and play crucial roles for this pedigree. Here we report of an ELN heterozygous variant associated with congenital heart disease accompanied with pulmonary artery stenosis, which is less common. Based on our results, we speculate that this may be the main molecular mechanism underlying the mutation-led functional changes, and propose that the decrease of ELN protein level may cause this pedigree vascular abnormality, especially pulmonary artery stenosis, and reinforce the view that ELN insufficiency is the primary cause of these vascular lesions. This may be the main molecular mechanism underlying the mutation-led functional changes. Thus, systematic analysis not only enables us to better understand the etiology of this disease but also contributes to clinical and prenatal diagnosis.

scholarly journals Correlation between cardiac catheterization and contrast enhanced MRI in pulmonary artery stenosis

2010 ◽  
Vol 12 (S1) ◽  
Author(s):  
Isra Valverde ◽  
Thomas Krasemann ◽  
Eric Rosenthal ◽  
Tarique Hussain ◽  
Hannah Bellsham-Revell ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Cardiac Catheterization ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

MR Imaging and MR Angiography of Pulmonary Artery Stenosis with Tubular Hypoplasia in Pregnancy

2000 ◽  
Vol 175 (5) ◽  
pp. 1462-1464
Author(s):  
Harp Bagga ◽  
Kostaki G. Bis
Keyword(s):  
Mr Imaging ◽  
Pulmonary Artery ◽  
Mr Angiography ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
In Pregnancy

scholarly journals Total Cavopulmonary Connection Flow With Functional Left Pulmonary Artery Stenosis

Circulation ◽  
2005 ◽  
Vol 112 (21) ◽  
pp. 3264-3271 ◽  
Author(s):  
Kerem Pekkan ◽  
Hiroumi D. Kitajima ◽  
Diane de Zelicourt ◽  
Joseph M. Forbess ◽  
W. James Parks ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Left Pulmonary Artery ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Total Cavopulmonary Connection ◽  
Cavopulmonary Connection

Severe peripheral pulmonary artery stenosis is not a contraindication to liver transplantation in Alagille syndrome

2006 ◽  
Vol 10 (1) ◽  
pp. 108-111 ◽  
Author(s):  
Figen Özçay ◽  
Birgül Varan ◽  
Kürşad Tokel ◽  
İlker Çetin ◽  
Aydın Dalgiç ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Pulmonary Artery ◽  
Alagille Syndrome ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis
Sign in / Sign up

Export Citation Format

Share Document