Flow Injection Spectrophotometric Determination of the Antibiotic Fosfomycin in Pharmaceutical Products and Urine Samples after On-line Thermal-Induced Digestion

2002 ◽  
Vol 304 (2) ◽  
pp. 244-248 ◽  
Author(s):  
Paraskevas D. Tzanavaras ◽  
Demetrius G. Themelis
Keyword(s):  
Spectrophotometric Determination ◽  
Flow Injection ◽  
Pharmaceutical Products ◽  
Urine Samples ◽  
On Line

Effect of on-line complex formation kinetics on the flow injection analysis signal: the spectrophotometric determination of chromium(VI)

The Analyst ◽  
1983 ◽  
Vol 108 (1286) ◽  
pp. 621 ◽  
Author(s):  
Jo�o Carlos de Andrade ◽  
Julio Cesar Rocha ◽  
Celio Pasquini ◽  
Nivaldi Baccan
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Flow Injection ◽  
Flow Injection Analysis ◽  
Line Complex ◽  
Chromium Vi ◽  
Formation Kinetics ◽  
On Line

Spectrophotometric determination of urinary iodine by flow-injection analysis with on-line catalytic digestion

1996 ◽  
Vol 42 (12) ◽  
pp. 2021-2027 ◽  
Author(s):  
Z Yaping ◽  
Y Dongxing ◽  
C Jixiang ◽  
L Tianshiu ◽  
C Huiqin
Keyword(s):  
Flow Injection ◽  
Reference Sample ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Urine Samples ◽  
Injection Technique ◽  
Freeze Dried ◽  
On Line ◽  
Iodine In Urine

Abstract A flow-injection technique involving on-line catalytic digestion and spectrophotometric detection has been developed for the determination of iodine in urine. After urine samples are digested by KMnO4-K2Cr2O7-H2SO4 solution, the iodine in the urine catalyzes the reaction of As(III) with Ce(IV). The remaining Ce(IV) is then reacted with brucine and the product is detected with a spectrophotometer at 480 nm. With this technique, we obtained a detection limit for urinary iodine of 0.039 mumol/L, and the linear range was 0.039-7.88 mumol/L with a CV < 3%. Analytical recovery ranged between 92% and 104% (mean 99%). The sampling frequency of the flow-injection technique was 70/h. We applied the method to measure the iodine concentration in a freeze-dried urine reference sample and in collected urine samples, and compared the results with those obtained by the accepted alkaline ashing technique. The proposed technique has the advantages of being simple, rapid, precise, accurate, and sensitive. It can be used to assess iodine-deficient populations as well as those receiving treatment.

Sign in / Sign up

Export Citation Format

Share Document