Characterization of HRG22, a Human Homologue of the Putative Tumor Suppressor Gene HIC1

2001 ◽  
Vol 287 (2) ◽  
pp. 427-434 ◽  
Author(s):  
Sophie Deltour ◽  
Sébastien Pinte ◽  
Cateline Guérardel ◽  
Dominique Leprince
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Human Homologue ◽  
Putative Tumor Suppressor Gene ◽  
Putative Tumor Suppressor

Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9

Cell ◽  
1992 ◽  
Vol 69 (1) ◽  
pp. 111-117 ◽  
Author(s):  
Mae R. Gailani ◽  
Sherri J. Bale ◽  
David J. Leffell ◽  
John J. DiGiovanna ◽  
Gary L. Peck ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Chromosome 9 ◽  
Gorlin Syndrome ◽  
Developmental Defects ◽  
Putative Tumor Suppressor Gene ◽  
Putative Tumor Suppressor

scholarly journals SHORT COMMUNICATION: Malignant conversion of human cells by antisense cDNA to a putative tumor suppressor gene

1996 ◽  
Vol 17 (8) ◽  
pp. 1751-1755 ◽  
Author(s):  
Dawei Li ◽  
Hua Yan ◽  
Jucheng Chen ◽  
Bruce C. Casto ◽  
Karl S. Theil ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Short Communication ◽  
Suppressor Gene ◽  
Human Cells ◽  
Putative Tumor Suppressor Gene ◽  
Putative Tumor Suppressor ◽  
Malignant Conversion

scholarly journals Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka

2018 ◽  
Vol 32 (2) ◽  
pp. 248-258 ◽  
Author(s):  
Janine Regneri ◽  
Barbara Klotz ◽  
Brigitta Wilde ◽  
Verena A. Kottler ◽  
Michael Hausmann ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Pigment Cells ◽  
Putative Tumor Suppressor Gene ◽  
Putative Tumor Suppressor

Sublocalization of putative tumor suppressor gene loci on chromosome arm 14q in neuroblastoma

1999 ◽  
Vol 26 (1) ◽  
pp. 40-46 ◽  
Author(s):  
Marco Theobald ◽  
Holger Christiansen ◽  
Anke Schmidt ◽  
Badrig Melekian ◽  
Nicole Wolkewitz ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Putative Tumor Suppressor Gene ◽  
Putative Tumor Suppressor ◽  
Chromosome Arm

Detailed Deletion Mapping of the Long Arm of Chromosome 6 in Adult T-Cell Leukemia

Blood ◽  
1999 ◽  
Vol 93 (2) ◽  
pp. 613-616 ◽  
Author(s):  
Yoshihiro Hatta ◽  
Yasuaki Yamada ◽  
Masao Tomonaga ◽  
Isao Miyoshi ◽  
Jonathan W. Said ◽  
...  
Keyword(s):  
T Cell ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Deletion Mapping ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Putative Tumor Suppressor Gene ◽  
Adult T Cell Leukemia ◽  
Putative Tumor Suppressor

Abstract Previously, we have found that the loss of heterozygosity (LOH) was frequently observed on chromosome 6q in acute/lymphoma-type adult T-cell leukemia (ATL), suggesting a putative tumor-suppressor gene for ATL may be present on chromosome 6q. To further define a region containing this gene, we performed fine-scale deletional mapping of chromosome 6q in 22 acute/lymphomatous ATL samples using 24 highly informative microsatellite markers. LOH was found in 9 samples (40.9%) at 1 or more of the loci examined. Of the 9 samples, 8 shared the same smallest commonly deleted region flanked by D6S1652 and D6S1644 (6q15-21). The genetic distance between these two loci is approximately 4 cM. These results suggest that a putative tumor-suppressor gene on chromosome 6q15-21 probably plays a very important role in the evolution of acute/lymphomatous ATL. Our map provides key information toward cloning the gene.

Sign in / Sign up

Export Citation Format

Share Document