Twenty-Seven Years Studying the Human Neurotoxicity of Methylmercury Exposure

2000 ◽  
Vol 83 (3) ◽  
pp. 275-285 ◽  
Author(s):  
G.J. Myers ◽  
P.W. Davidson ◽  
C. Cox ◽  
C. Shamlaye ◽  
E. Cernichiari ◽  
...  
Keyword(s):  
Methylmercury Exposure

Risk and Regulation: Methylmercury Exposure and Fish Consumption

2010 ◽  
Vol 6 ◽  
Author(s):  
Jonathan M Gendzier
Keyword(s):  
Environmental Protection Agency ◽  
Fish Consumption ◽  
Government Regulation ◽  
Mercury Emissions ◽  
Methylmercury Exposure ◽  
Exposure Levels ◽  
Aquatic Food ◽  
Reference Doses ◽  
Fish And Shellfish ◽  
Global Cycle

Exposure to organic mercury (methylmercury) occurs almost universally due to ingestion via contaminated fish and shellfish tissue. Ultimate sources of mercury consist of air release by domestic industrial combustion, mining, and international mercury emissions transported via a global cycle. Deposition of mercury from air to surface waters results in methylation to organic methylmercury and bioaccumulation in the aquatic food web. Health effects from methylmercury exposure consist mainly of neurological and neurodevelopmental effects, with fetuses particularly sensitive. Thus regulation of methylmercury exposure has concentrated on acceptable exposure levels and reference doses aimed toward protecting developing fetuses. The risk of methylmercury exposure in humans is regulated largely by the federal government, especially by the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA). The EPA imposes limits on mercury emissions and seeks to research methylmercury levels in fish and humans. The EPA sets a reference dose for methylmercury exposure. The FDA conducts uses date on methylmercury levels in fish to advise consumers on how to make informed decisions regarding fish consumption. There are numerous shortcoming to government regulation of this issue. Further scientific research, improved implementation of available data and scientific conclusions, and improved public communication of risk would all lead to more effective treatment of the risk of methylmercury exposure via ingestion of fish and shellfish. This could include more effective monitoring systems of human and fish methylmercury levels, research into the process of bioaccumulation, and implementation of stricter fish labeling standards, as well as research into higher-risk subpopulations allowing for targeted standards and recommendations.

scholarly journals Cognitive deficits and changes in gene expression of NMDA receptors after prenatal methylmercury exposure.

2002 ◽  
Vol 110 (suppl 5) ◽  
pp. 855-858 ◽  
Author(s):  
Mario Baraldi ◽  
Paola Zanoli ◽  
Fabio Tascedda ◽  
Joan M C Blom ◽  
Nicoletta Brunello
Keyword(s):  
Gene Expression ◽  
Nmda Receptors ◽  
Cognitive Deficits ◽  
Methylmercury Exposure

scholarly journals Methylmercury exposure, PON1 gene variants and serum paraoxonase activity in Eastern James Bay Cree adults

2014 ◽  
Vol 24 (6) ◽  
pp. 608-614 ◽  
Author(s):  
Olivia Drescher ◽  
Eric Dewailly ◽  
Caroline Diorio ◽  
Nathalie Ouellet ◽  
Elhadji Anassour Laouan Sidi ◽  
...  
Keyword(s):  
Gene Variants ◽  
James Bay ◽  
Paraoxonase Activity ◽  
Pon1 Gene ◽  
James Bay Cree ◽  
Methylmercury Exposure ◽  
Serum Paraoxonase

Prenatal methylmercury exposure results in dendritic spine dysgenesis in rats

1990 ◽  
Vol 12 (6) ◽  
pp. 573-576 ◽  
Author(s):  
Gisela Stoltenburg-Didinger ◽  
Susanne Markwort
Keyword(s):  
Dendritic Spine ◽  
Methylmercury Exposure

Mitochondrial transduction of ocular teratogenesis during methylmercury exposure

Teratology ◽  
2002 ◽  
Vol 65 (3) ◽  
pp. 131-144 ◽  
Author(s):  
Michael F. O'Hara ◽  
Jeffrey H. Charlap ◽  
Robert C. Craig ◽  
Thomas B. Knudsen
Keyword(s):  
Methylmercury Exposure

Methylmercury exposure assessment using dietary and biomarker data among frequent seafood consumers in France

2008 ◽  
Vol 107 (1) ◽  
pp. 30-38 ◽  
Author(s):  
Véronique Sirot ◽  
Thierry Guérin ◽  
Yves Mauras ◽  
Hervé Garraud ◽  
Jean-Luc Volatier ◽  
...  
Keyword(s):  
Exposure Assessment ◽  
Methylmercury Exposure ◽  
Biomarker Data

The effects of methylmercury exposure on behavior and biomarkers of oxidative stress in adult mice

2015 ◽  
Vol 50 ◽  
pp. 170-178 ◽  
Author(s):  
Meg Kirkpatrick ◽  
Janina Benoit ◽  
Wyll Everett ◽  
Jennifer Gibson ◽  
Michael Rist ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adult Mice ◽  
Methylmercury Exposure ◽  
Biomarkers Of Oxidative Stress

scholarly journals Methylmercury exposure and cognitive abilities and behavior at 10 years of age

2017 ◽  
Vol 102 ◽  
pp. 97-105 ◽  
Author(s):  
Klara Gustin ◽  
Fahmida Tofail ◽  
Fardina Mehrin ◽  
Michael Levi ◽  
Marie Vahter ◽  
...  
Keyword(s):  
Cognitive Abilities ◽  
Methylmercury Exposure ◽  
And Behavior
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