In Vitro cDNA Amplification from Individual Intestinal Crypts: A Novel Approach to the Study of Differential Gene Expression along the Crypt-Villus Axis

1993 ◽  
Vol 208 (2) ◽  
pp. 344-349 ◽  
Author(s):  
Danielle F. Cano-Gauci ◽  
John C. Lualdi ◽  
André J. Ouellette ◽  
Gerard Brady ◽  
Norman N. Iscove ◽  
...  
Keyword(s):  
Gene Expression ◽  
Differential Gene Expression ◽  
Novel Approach ◽  
Differential Gene

Cryptococcus neoformans Differential Gene Expression Detected In Vitro and In Vivo with Green Fluorescent Protein

1999 ◽  
Vol 67 (4) ◽  
pp. 1812-1820
Author(s):  
Maurizio del Poeta ◽  
Dena L. Toffaletti ◽  
Thomas H. Rude ◽  
Sara D. Sparks ◽  
Joseph Heitman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Green Fluorescent Protein ◽  
Cryptococcus Neoformans ◽  
Differential Gene Expression ◽  
Fluorescent Protein ◽  
Differential Gene ◽  
Green Fluorescent

scholarly journals Discovering therapeutic activities from venoms using differential gene expression

2019 ◽  
Author(s):  
Joseph D. Romano ◽  
Hai Li ◽  
Ronald Realubit ◽  
Charles Karan ◽  
Nicholas P. Tatonetti
Keyword(s):  
Gene Expression ◽  
Differential Gene Expression ◽  
Regulatory Networks ◽  
Preliminary Evidence ◽  
Natural Toxins ◽  
Differential Gene ◽  
Public Repositories ◽  
Therapeutic Activities ◽  
Validation Experiments

AbstractVenoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous informatics approaches for discovering new therapeutic activities are scarce. We have designed and validated a new platform—named VenomSeq—to systematically generate putative associations between venoms and drugs/diseases via high-throughput transcriptomics and perturbational differential gene expression analysis. In this study, we describe the architecture of VenomSeq, and its evaluation using the crude venoms from 25 diverse animal species. By integrating comparisons to public repositories of differential expression, associations between regulatory networks and disease, and existing knowledge of venom activity, we provide a number of new therapeutic hypotheses linking venoms to human diseases supported by multiple layers of preliminary evidence. We are currently performing validation experiments in vitro to corroborate these findings.

scholarly journals The Temporal Dynamics of Differential Gene Expression in Aspergillus fumigatus Interacting with Human Immature Dendritic Cells In Vitro

PLoS ONE ◽  
2011 ◽  
Vol 6 (1) ◽  
pp. e16016 ◽  
Author(s):  
Charles O. Morton ◽  
John J. Varga ◽  
Anke Hornbach ◽  
Markus Mezger ◽  
Helga Sennefelder ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dendritic Cells ◽  
Aspergillus Fumigatus ◽  
Differential Gene Expression ◽  
Temporal Dynamics ◽  
Immature Dendritic Cells ◽  
Differential Gene

Investigating Differential Gene Expression in Response to Ovarian Steroid Manipulation in Vitro in Perimenopausal and Postpartum Depression

2021 ◽  
Vol 89 (9) ◽  
pp. S8
Author(s):  
Sarah Rudzinskas ◽  
Jessica Hoffman ◽  
Allison Goff ◽  
Maria Mazzu ◽  
Crystal Schiller ◽  
...  
Keyword(s):  
Gene Expression ◽  
Postpartum Depression ◽  
Differential Gene Expression ◽  
Ovarian Steroid ◽  
Differential Gene

scholarly journals Differential gene expression between in vivo and in vitro maturation: a comparative study with bovine oocytes derived from the same donor pool

2019 ◽  
Author(s):  
Luiz Sergio Almeida Camargo ◽  
Michele Munk ◽  
Jose Nelio Sales ◽  
Sabine Wohlres-Viana ◽  
Carolina Capobiango Romano Quintão ◽  
...  
Keyword(s):  
Gene Expression ◽  
Comparative Study ◽  
Differential Gene Expression ◽  
In Vitro Maturation ◽  
Donor Pool ◽  
Differential Gene ◽  
Bovine Oocytes
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