Recombinant Adeno-associated Viral Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Protects Nigral Dopamine Neurons after Onset of Progressive Degeneration in a Rat Model of Parkinson's Disease

R.J. Mandel; R.O. Snyder; S.E. Leff

doi:10.1006/exnr.1999.7203

Recombinant Adeno-associated Viral Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Protects Nigral Dopamine Neurons after Onset of Progressive Degeneration in a Rat Model of Parkinson's Disease

Experimental Neurology ◽

10.1006/exnr.1999.7203 ◽

1999 ◽

Vol 160 (1) ◽

pp. 205-214 ◽

Cited By ~ 67

Author(s):

R.J. Mandel ◽

R.O. Snyder ◽

S.E. Leff

Keyword(s):

Parkinson’S Disease ◽

Gene Transfer ◽

Cell Line ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor ◽

Viral Vector ◽

Dopamine Neurons ◽

Factor Gene ◽

Progressive Degeneration

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Protection by Synergistic Effects of Adenovirus-Mediated X-Chromosome-Linked Inhibitor of Apoptosis and Glial Cell Line-Derived Neurotrophic Factor Gene Transfer in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Model of Parkinson's Disease

Journal of Neuroscience ◽

10.1523/jneurosci.20-24-09126.2000 ◽

2000 ◽

Vol 20 (24) ◽

pp. 9126-9134 ◽

Cited By ~ 142

Author(s):

Olaf Eberhardt ◽

Rainer V. Coelln ◽

Sebastian Kügler ◽

Jörg Lindenau ◽

Silvia Rathke-Hartlieb ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Gene Transfer ◽

Cell Line ◽

Glial Cell ◽

X Chromosome ◽

Neurotrophic Factor ◽

Synergistic Effects ◽

Inhibitor Of Apoptosis ◽

Factor Gene

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An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease

Journal of Neuroscience ◽

10.1523/jneurosci.2440-10.2010 ◽

2010 ◽

Vol 30 (49) ◽

pp. 16469-16474 ◽

Cited By ~ 47

Author(s):

J. Laganiere ◽

A. P. Kells ◽

J. T. Lai ◽

D. Guschin ◽

D. E. Paschon ◽

...

Keyword(s):

Parkinson’S Disease ◽

Cell Line ◽

Glial Cell ◽

Zinc Finger ◽

Rat Model ◽

Neurotrophic Factor ◽

Zinc Finger Protein ◽

Factor Gene ◽

Protein Activator ◽

Finger Protein

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Nonviral Glial Cell-Derived Neurotrophic Factor Gene Transfer Enhances Survival of Cultured Dopaminergic Neurons and Improves Their Function after Transplantation in a Rat Model of Parkinson’s Disease

Human Gene Therapy ◽

10.1089/10430340050083261 ◽

2000 ◽

Vol 11 (11) ◽

pp. 1529-1541 ◽

Cited By ~ 19

Author(s):

Matthias Bauer ◽

Morten Meyer ◽

Lena Grimm ◽

Thomas Meitinger ◽

Jens Zimmer ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Gene Transfer ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor ◽

Dopaminergic Neurons ◽

Factor Gene

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Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model

The Journal of Gene Medicine ◽

10.1002/jgm.1377 ◽

2009 ◽

Vol 11 (10) ◽

pp. 899-912 ◽

Cited By ~ 28

Author(s):

Xin Yang ◽

Birgit Mertens ◽

Enni Lehtonen ◽

Linda Vercammen ◽

Olivier Bockstael ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Gene Delivery ◽

Cell Line ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor ◽

Factor Gene ◽

Neurochemical Changes

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Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease

Molecular Brain Research ◽

10.1016/j.molbrainres.2004.06.029 ◽

2005 ◽

Vol 134 (1) ◽

pp. 155-161 ◽

Cited By ~ 29

Author(s):

Jie-Sheng Zheng ◽

Ling-Ling Tang ◽

Shu-Sen Zheng ◽

Ren-Ya Zhan ◽

Yong-Qing Zhou ◽

...

Keyword(s):

Parkinson’S Disease ◽

Gene Therapy ◽

Parkinson's Disease ◽

Cell Line ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor

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Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson's disease

Neuroscience ◽

10.1016/s0306-4522(97)00269-8 ◽

1997 ◽

Vol 82 (1) ◽

pp. 129-137 ◽

Cited By ~ 109

Author(s):

C Rosenblad ◽

A Martinez-Serrano ◽

A Björklund

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cell Line ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor ◽

Recovery Of Function

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Adeno-Associated Virus Type 2 Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Induces Neuroprotection and Neuroregeneration in a Ubiquitin-Proteasome System Impairment Animal Model of Parkinsons Disease

Neurodegenerative Diseases ◽

10.1159/000334527 ◽

2013 ◽

Vol 11 (3) ◽

pp. 113-128 ◽

Cited By ~ 8

Author(s):

Yunlan Du ◽

Xiaojie Zhang ◽

Qingqing Tao ◽

Sheng Chen ◽

Weidong Le

Keyword(s):

Animal Model ◽

Gene Transfer ◽

Cell Line ◽

Glial Cell ◽

Neurotrophic Factor ◽

Ubiquitin Proteasome System ◽

Adeno Associated Virus ◽

Factor Gene ◽

Ubiquitin Proteasome

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Glial Cell Line–Derived Neurotrophic Factor Gene Transfer Exerts Protective Effect on Axons in Sciatic Nerve Following Constriction-Induced Peripheral Nerve Injury

Human Gene Therapy ◽

10.1089/hum.2010.036 ◽

2011 ◽

Vol 22 (6) ◽

pp. 721-731 ◽

Cited By ~ 17

Author(s):

Jhih-Yin Shi ◽

Guei-Sheung Liu ◽

Li-Feng Liu ◽

Shiao-Mei Kuo ◽

Cha-Hwa Ton ◽

...

Keyword(s):

Gene Transfer ◽

Sciatic Nerve ◽

Peripheral Nerve ◽

Protective Effect ◽

Cell Line ◽

Glial Cell ◽

Nerve Injury ◽

Neurotrophic Factor ◽

Peripheral Nerve Injury ◽

Factor Gene

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385. An Engineered Transcriptional Activator of Glial Cell Line-Derived Neurotrophic Factor Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease

Molecular Therapy ◽

10.1016/s1525-0016(16)38743-3 ◽

2009 ◽

Vol 17 ◽

pp. S150

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cell Line ◽

Glial Cell ◽

Rat Model ◽

Neurotrophic Factor ◽

Transcriptional Activator

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Aberrant Sprouting and Downregulation of Tyrosine Hydroxylase in Lesioned Nigrostriatal Dopamine Neurons Induced by Long-Lasting Overexpression of Glial Cell Line Derived Neurotrophic Factor in the Striatum by Lentiviral Gene Transfer

Experimental Neurology ◽

10.1006/exnr.2002.8006 ◽

2002 ◽

Vol 177 (2) ◽

pp. 461-474 ◽

Cited By ~ 158

Author(s):

B Georgievska

Keyword(s):

Tyrosine Hydroxylase ◽

Gene Transfer ◽

Cell Line ◽

Glial Cell ◽

Neurotrophic Factor ◽

Dopamine Neurons ◽

Nigrostriatal Dopamine ◽

Nigrostriatal Dopamine Neurons

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Recombinant Adeno-associated Viral Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Protects Nigral Dopamine Neurons after Onset of Progressive Degeneration in a Rat Model of Parkinson's Disease

Protection by Synergistic Effects of Adenovirus-Mediated X-Chromosome-Linked Inhibitor of Apoptosis and Glial Cell Line-Derived Neurotrophic Factor Gene Transfer in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Model of Parkinson's Disease

An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease

Nonviral Glial Cell-Derived Neurotrophic Factor Gene Transfer Enhances Survival of Cultured Dopaminergic Neurons and Improves Their Function after Transplantation in a Rat Model of Parkinson’s Disease

Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model

Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease

Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson's disease

Adeno-Associated Virus Type 2 Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Induces Neuroprotection and Neuroregeneration in a Ubiquitin-Proteasome System Impairment Animal Model of Parkinsons Disease

Glial Cell Line–Derived Neurotrophic Factor Gene Transfer Exerts Protective Effect on Axons in Sciatic Nerve Following Constriction-Induced Peripheral Nerve Injury

385. An Engineered Transcriptional Activator of Glial Cell Line-Derived Neurotrophic Factor Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease

Aberrant Sprouting and Downregulation of Tyrosine Hydroxylase in Lesioned Nigrostriatal Dopamine Neurons Induced by Long-Lasting Overexpression of Glial Cell Line Derived Neurotrophic Factor in the Striatum by Lentiviral Gene Transfer

Adeno-Associated Virus Type 2 Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Induces Neuroprotection and Neuroregeneration in a Ubiquitin-Proteasome System Impairment Animal Model of Parkinsons Disease